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And is there a way to bring sense to the world? I wonder sometimes.

Yes, the goal is for GPs to take over the world and provide a really crap service on their own. Sadly the likely incoming government in the UK is all for that approach too. What happened to high quality care?

That looks like a calibration artefact to me. You have to be ever so careful about cross-calibrating these assays. Part of the problem is that the scale changes from 10 to 60 days per gradation. But there is something else odd going on. Antibody profiles after B depletion are always...

I guess the question is why Charles Shepherd and the MEA are putting out messages linking to rubbish like this. I find it all rather puzzling. More than anything it is just the lack of discernment.

This is a complete garbage article typical of what comes out of the Primary Care Medicine camp. Apparently it is supported by Versus Arthritis and Royal College of Physicians which is an indication of just how much standards have slipped in forty years. These people are just making things up...

I wonder if there are any pilot study data? The trial linked to looks cumbersome and without any clear primary outcome measure. (The description of the outcome measures is very peculiar, with all benefit 'outcomes' being called secondary.) I am unclear exactly what patients are going to be...

I don't think anyone should be trying to frame it other than as not understood and needing a lot more attention. Endless quoting of weak and unreproducible evidence about this or that finding just confuses people and lines the pockets of immunobabblers and the like.

Perhaps PWME should try speaking with a Welsh Accent: 'Cariad. Sto-op, Look you.' perhaps. It could deal with the ME/CFS very well. I can see that it is nice to have an explanation but maybe the brain didn't actually know why it was using a Welsh Accent? Maybe the professor didn't know...

I doubt it. It might possibly be useful as part of a combination therapy but I have no idea with what.

I think I would be happy to say that in general in medical science once you have hit on the right thing to measure the difference you are looking for isn't hard to spot. There are exceptions. Using PCR to find micro-organisms in blood is a good example. You won't see them down a microscope...

If it ducks like a quack, there is a high chance...

Thanks for the input Adam. I just find it hard to think who could have come up with such amateurish material. It seems that the working group involved had no power to inject some common sense. There are people around who could have written very good learning modules - you for instance! We need...

Very disappointing. I find Sonya Chowdhury's media releases much sharper these days.

The strange thing is that it seems that all these authors (pretty much) are students or very junior. Some involved in psychology, some sport. Some of them have an interest in ME/CFS/. Maybe somebody hoped they could show GWI people had PEM. But why say exercise benefits outweigh risks? It's...

I wonder who dreamt this up? The scientific stuff is all complete nonsense. It is embarrassingly disappointing that a medical education package should be as poor as this. Medical education used to stick to established facts pretty well. This reads a bit like a 1970s textbook of 'Physiology for...

They clearly didn't work hard enough on their placebo effect.

The electron microscope allowed us to diagnose minimal change glomerulonephritis, but in general I agree. Sensitivity of test is rarely important.

Not just self-important rambling, but global neuronal working space self-important rambling. You need to get the full nuance! And bad science while we're about it.

A fairly sobering analysis.

As Voltaire and mark Twain said, common sense isn't that common.