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  1. Jonathan Edwards

    Exercise Training in Post-COVID-19 Patients: The Need for a Multifactorial Protocol for a Multifactorial Pathophysiology, 2022, Cattadori et al

    But isn't it that as well? I am now three weeks from starting Covid-19 (second bout). I am probably 2 weeks from severe symptoms and a week from mild/moderate. There is no way that I would see any reason to undertake an exercise program. I have been doing odds and ends of things that I might...
  2. Jonathan Edwards

    Most healthcare interventions tested in Cochrane Reviews are not effective according to high quality evidence: a systematic re..., 2022, Schmidt et al

    I have been through it. It is pretty much what it says on the tin - very few treatments come out with high quality evidence on Cochrane reviews and harms are under-reported and common. But the pinch of salt is that they think GRADE is great and maybe even a bit strict. On the other hand that...
  3. Jonathan Edwards

    UK NICE 2021 ME/CFS Guideline, published 29th October - post-publication discussion

    Absolutely not, because the BPS people have no evidence to make such claims - (other than where the NICE guideline is in fact at fault that is.) If the idea is to pass on what the NICE guideline says verbatim then it should be presented like that - or just give the URL for the guideline. If the...
  4. Jonathan Edwards

    UK NICE 2021 ME/CFS Guideline, published 29th October - post-publication discussion

    In the abstract yes, but I don't buy this as an excuse. The NICE committee had an ethical duty to produce a guideline based on reliable evidence and good rational argument. They did pretty well but on this point they muffed it. To my mind anyone writing on a website that appears to be...
  5. Jonathan Edwards

    Magnesium

    But is that right? As far as I am aware clinical magnesium deficiency is largely limited to specific conditions where it will be expected - like severe renal disease or malabsorption. I don't see any reason to think PWME are likely to need to take magnesium. That looks highly implausible. The...
  6. Jonathan Edwards

    UK NICE 2021 ME/CFS Guideline, published 29th October - post-publication discussion

    I don't see it as a consequence. To repeat it as advice you have to think it merits repeating. Strain wasn't on the committee so I don't see that he is obliged to repeat it.
  7. Jonathan Edwards

    The Relationship between Physical Activity and Long COVID: A Cross-Sectional Study, 2022, Wright et al

    Not really. You wait until you are ready. Unless someone discovers how to get rid of LC symptoms, but that is another matter.
  8. Jonathan Edwards

    UK NICE 2021 ME/CFS Guideline, published 29th October - post-publication discussion

    So who produces and funds Medscape? We seem to live in a world of predigested information served up 'on message' in line with nobody quite knows who.
  9. Jonathan Edwards

    UK NICE 2021 ME/CFS Guideline, published 29th October - post-publication discussion

    I am wondering what 'Guidelines' is - who produces it and who funds it and what relation if any it has to NICE? I find this article quite disappointing because it seems to be a mish mash of repeated material from various sources rolled into a 'recipe' without any background thought. Why is CBT...
  10. Jonathan Edwards

    B12/Folic Acid and D3/K2 Supplementation

    If he had been ill and not eating much that might be relevant to a low folate level but I doubt it has anything to do with the Covid, or vice versa. We have just had our second Covid after three jabs and it is pretty draining - now nearly three weeks in. I don't think all the stuff about...
  11. Jonathan Edwards

    an ‘invisible’ illness that benefits from a relationship-based care approach – BJGP Life, 2022

    Ethnography is also a type of social research that involves examining the behaviour of the participants in a given social situation and understanding the group members' own interpretation of such behaviour.[3] That sounds like 'gossip' to me. So this is meta-gossip: gossip about gossip.
  12. Jonathan Edwards

    Covid-19 vaccines and vaccinations

    Believing that people have the symptoms they have is a completely different thing from accepting causal explanations based on individual cases that can never be proven. Coincidences occur all the time. The only way to establish that there is a causal link is to do large systematic studies...
  13. Jonathan Edwards

    Who is Simon Wessely?

    What with the ex-king of Spain and some of the Windsors, being royalty isn't necessarily something to be proud of these days!
  14. Jonathan Edwards

    Symptoms of Idiopathic Environmental Intolerance associated with chemicals (IEI-C) are positively associated with perceptual anomalies, 2022, Speck

    I don't think medics would deny that odours can trigger symptoms. Nausea, streaming eyes and nose and all sorts of other things are symptoms triggered by odours everyone recognises. Where I think the medical profession is justified is in being sceptical about calling this 'Multiple Chemical...
  15. Jonathan Edwards

    Covid-19 vaccines and vaccinations

    About 20 people, now up to 37, testified in a closed Facebook group to exactly the same kind of symptoms: numbness, tingling, a feeling of fire in the body, tinnitus, all linked to the time of vaccination, often immediately after injection. For a population of ten million you would expect at...
  16. Jonathan Edwards

    an ‘invisible’ illness that benefits from a relationship-based care approach – BJGP Life, 2022

    It all sounds very nice but reminds me of the Round Table member who introduced themselves as the 'friendly sort of psychiatrist (with artificial smile) presumably to distinguish them from people who do trials of GET and CBT, although those surely should not be dismissed out of hand... If GPs...
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