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  1. shak8

    Understanding the Psychophysiological and Sensitization Mechanisms behind Fibromyalgia Syndrome: A Network Analysis Approach, 2022, Varol et al

    Researchers are physiotherapists in two centers in Spain. What do these phrases actually mean (I don't have access to the full study): "psychophysical" and the "cllnical sensory-related" for the variables. Many of the variables are clearly related such as pain intensity and anixety and...
  2. shak8

    Association of Vitamin B12, Vitamin D, and Thyroid-Stimulating Hormone With Fatigue and Neurologic Symptoms in ... Fibromyalgia, 2022, Munipalli et al

    They used retroactively patients who already had those lab tested done (Vit D and B12). Could that fact limit the uselfulness of the study? It could be that those lab tests were ordered precisely because the patients had outstanding (more than the usual per FM) symptoms pointing to Vit D and...
  3. shak8

    UK healthcare services for people with fibromyalgia: results from two web-based national surveys (the PACFiND study), 2022, Wilson et al

    I have a hard time with these practitioners and their problems. They seem to be lacking some important traits. Like patience, compassion, dedication. If I were their supervisor in clinical rotation, I would have suggested an alternative career, such as auto mechanics. Jeez. I got diagnosed with...
  4. shak8

    Visual Imagery and chronic pain - new study at Bath (Jo Daniels supervisor)

    i have never had a visual image of my pain (FM). I assume the researcher thinks they will change such visual images and thus change the pain. However, due to my incredulity viz a viz this article, I've started to yell at my pain. I feel better already.
  5. shak8

    Effects of the Prolong Life With Nine Turn Method (Yan Nian Jiu Zhuan) Qigong on Brain Functional Changes in Patients With CFS, 2022, Xie et al

    I have trouble taking any research from traditional Chinese medicine academies seriously.
  6. shak8

    An Integrative Neuropsychological Approach to Chronic Pain, Emotions and Clinical Symptoms, 2022, Montoro and Galvez-Sánchez

    As a PwFM, I will (n=1) attest that adequate pain relief in fibromyalgia is attainable through medication only, if then. When pain is relieved, a miracle has occurred and one's mood shifts correspondingly. Moderate to severe pain is inherently catastrophic to the patient. That's the function...
  7. shak8

    When It Hurts, a Positive Attitude May Help. The Moderating Effect of Positive Affect ... in Women with Fibromyalgia, 2022, Ecjia et al

    I love how the researchers had to modify their protocol of 60 minutes of walking in 20 minute bouts with short rest periods. If they had read extensive literature, they would have begun with 20 minutes.
  8. shak8

    Altered serum bile acid profile in fibromyalgia is associated with specific gut microbiome changes and symptom severity, 2022, Minerbi et al

    Why bile acids? What is their significance in the totality of the microbiome? 42 subjects and 42 controls, paltry.
  9. shak8

    Aphaeresis/ Apheresis (for removal of microclots)

    Dialysis which I've performed removes excess electrolytes like potassium and sodium and adds a bit of bicarb buffer to the acidic blood. Excess urea is removed (patients smell a bit bad when they come in for their treatments). Proteins, like albumin are large and do not cross the membrane of the...
  10. shak8

    Long Covid in the media and social media 2022

    I left a comment on the TVIV website on the "leave comments" section addressing your concerns, I think. The virologists and Paul Offit should not have been so cavalier in their ha-ha it's only fatigue comments and laughter--it hurts and it's wrong. All they need to say is: we are not clinicians...
  11. shak8

    Long Covid in the media and social media 2022

    I would count their facetious treatment of fatigue as a symptom of their lack of expertise in the area of long covid. Everyone in the panel has her or his limitations in how much they know and dependent on what their area of specialization is. Offit is a vaccine expert. Well worth listening to...
  12. shak8

    News From Jarred Younger / Neuroinflammation, Pain, and Fatigue Laboratory at UAB, From Aug 2020

    Younger has already done trials of various herbs, a shot-gun approach, if you will. He has already done small naltrexone studies. The "let's trial any substance folks say works" does not inspire confidence.
  13. shak8

    USA: Massachusetts ME/CFS & FM Association news

    Making a general statement here. There's a big contingent of American woo in advocacy organizations and even some university research departments. The dissatisfaction with the way the medical establishment 'operated' 20 years ago or so, or the limits of what medicine knows and can do, led to...
  14. shak8

    I wrote a short story about ME/CFS

    Great imagination. Kind of shook me in a good way.
  15. shak8

    PEM for those who are, or were, mild sufferers, how would you describe it?

    I think I experience PEM occasionally when overdoing or when getting sick with a bug. I resist the IOM diagnosis of ME because I don't feel severe fatigue at least half the time. Have no OI either. Maybe there is in me an overlap of FM/ME. But anyway, I had been coping with recent anxiety by...
  16. shak8

    Clinical overlap between fibromyalgia and myalgic encephalomyelitis. A systematic review and meta-analysis, 2022, Ramírez-Morales et al

    We have no molecular mechanisms identified for either illness to distinguish them. In people with systemic autoimmune disease there is a lot of co-existing diagnosis and symptoms of FM. Does one cause the other, or are they related in molecular origins, are some of the symptoms too similar to...
  17. shak8

    Distinct CholinomiR Blood Cell Signature as a Potential Modulator of the Cholinergic System in Women with Fibromyalgia, 2022, Christoph Eracher et al

    Anti-cholinergic treatment is effective in FMS patient subgroups, and cholinergic signaling is a strong modulator of CNS and PNS immune processes..." news to me. Which drug might that be? This research (and I have absolutely no competence in assessing it) seems overly speculative and...
  18. shak8

    Specific documents on CFS and fibromyalgia from a US agency (Job Accommodation Network) (2008)

    Nice to see some updated accommodations suggestions in the above since my time consulting the list in 1999 when I had to apply for disability (FM).
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