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The more I think about it and review the De-Paul Symptom questionnaire, the more I think it’s appropriate to say using the DSQ to measure PEM is the equivalent of using the Oxford criteria to measure ME/CFS.

Yes. I’m a little worried the story of long COVID will echo the story of ME. Lots of people start claiming it’s caused by persistent virus with insufficient evidence. Over time, with lack of replication and strong evidence the house of cards gets toppled. Then, psychosomatisers come in and fill...

Not really thanks for pointing that out. I sometimes use the search function and I didn’t realise this post was that old!

I find that to be a deeply worrying and inappropriate reply on his end.

Anedotal evidence (part of my family is french) very much supports that. Also I found this new article by Science based medicine well done https://sciencebasedmedicine.org/homeopathy-magical-thinking-not-medicine/?utm_source=rss&utm_medium=rss&utm_campaign=homeopathy-magical-thinking-not-medicine

I wonder if they differ depending on other factors in the same person. I’ve had wildly different responses to overexertion depending on how much I push it. It can be anywhere from inducing massive “adrenaline rush” that has me overexerting for weeks until I crash to immediately feeling like I...

Yes. I don’t know what malaise means in english, but from my french intuition “PEM” is practically as bad as “CFS”. To me when I first hear post exertional malaise it sounds like nausea and lightheadedness for a couple minutes after exercise. (what you get when you didn’t eat enough in the...

If it’s not standard practice to republish in these circumstances, this is pretty outrageous.

Okay the republishing annoyed me so much I shared the petition on my instagram which has all my friends from before I got sick, many of whom do not know I am sick. A bit nervous about that but it had to be done.

Added comment about the new review process being abandoned.

Yes for sure. But it’s got the aesthetic of and the cultural recognition as “science” therefore it is accepted as scientific in our cultural paradigms, even though it is incompatible with the scientific method. “sciencewashing”?

Do you think they did it on purpose to update the date? If so that is indeed outrageous.

I don’t wish to disparage relgion but it does feel quite equivalent to someone in the past suffering from illness, who prayed to a deity that they would get better and did indeed get better. Therefore they decide their deity saved them, and that everyone else who stays ill or dies of the illness...

It’s compatible with the literature in a small psychsomatic echo chamber. They are the self appointed experts on FND (since they created it), and therefore they must be correct. Their papers serve as a self admirtion society, consistently hyping up each others theories without bringing sound...

It’s so weird being patronised by “recovered people”. It’s like if back in the day people who recovered after a nasty bout of polio spent insane amounts of time telling those got paralytic polio (leading to long term disability) how to think yourself out of the illness and recover. Like what...

(Guest Editorial) No Abstract Provided — First two paragraphs This editorial highlights two elegant articles published recently about the stress response in health and disease: Agorastos and Chrousos [1] and de Kloet and Joels [2]. Chrousos, the senior author of the first paper, is arguably...

I was rethinking about that appointment I had where I got diagnosed with FND and I remembered an interesting detail. (Note this is significant because the doctor I saw is officially a researcher in the neurological consequences of COVID, helped write the country guidelines for long COVID, and...

In the sense that they both stimulate sensory neurons, they could share the same mechanistic pathways.

That’s a good point! I’m basing this on no immune knowledge at all, but I was under the impression that cytotoxic NK cells were the ones who mainly produced cytotoxicity as opposed to other types, but yes I had not considered other types may still produce it or adapt. The body is a lot more...

That’s possible, I’m not familiar with how “cytotoxicity” is measured, is it in relation to a single cell (or an average thereof)? If yes, then you are correct. Though I would guess a lower number of cytotoxic NK cells would correlate with an average of lower cytotoxicity among NK cells.