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I thought that the reference was in the Little Red Book www.imet.ie/imet_documents/BYRON_HYDE_little_red_book.pdf in which he refers to the meeting in the section starting at p10. I see that this does not include the comments about Beard. I shall have to look further for the source of those.

Interesting to see that NESTA received is said to have received an initial endowment of £250million from the National Lottery. Never knew that was the aim of the National Lottery.

@ScottTriGuy I believe that Dr Hyde has written about those events before. As I recall it he previously went further on the subject of his discussions with McEvedy, which took place over a bottle of whisky. There was a suggestion of links of Beard to the insurance industry. It would be...

Will all those who wish to take part in the trial to establish whether drinking pints of cider increases the chance of succumbing to ME, or worsens the chance of recovery from it, please form an orderly queue?

There is also this intriguing reference; The strongest evidence, however implicates Coxsackie viruses. These are known to be myotropic, as in Bornholm disease. They show an increased ability to replicate in muscle which has been denervated 16, or severely exercised 17.In the latter case they...

That is certainly how it felt. The further point arises when the switching appears to follow a particular pattern rather than being entirely random. If switching is random one can believe in an unstable system, but when the switching appears to be regular does not the switching have to be a...

No, I don't think it is that, although it may, temporarily, look similar.

I was struck by Jen's description of right sided weakness which apparently made her think of atypical polio. This symptom has been referred to by a number of people, including me. I was at one time noting whom but have of course forgotten. Some have referred to left sided weakness. It is a...

What @JenB has described seems to me a very good statement of the sudden, spontaneous, and, unfortunately, frequent relapse for which the term Post Exertional Malaise does not begin to do justice, and is in fact wholly inadequate and misleading. The question which I would put to those who do...

Yes, I get that, but it seems a little naïve and amateurish to be so blatant about it.

It would be interesting to know who it was that came up with the name PACE. Was it a committee decision, or did someone present thee idea to them? It is so Orwellian that it would be useful to know.

At least we now know why he gives us that sinking feeling. He gives himself it, too.

Hi @Nasim Marie Jafry Thanks for putting me right on that. For anyone interested in the complexities of the polio epidemics at a personal level this discussion with Shelokov is interesting. https://history.nih.gov/archives/downloads/ashelokov.pdf From about p48 he discusses the possibility of...

I am not sure that anyone is saying that ME is atypical polio. There may however be a case for arguing that a subset of patients have their illness triggered by a virus related to the polio viruses and which has evaded discovery. In any event it could be argued that "polio" is atypical polio in...

There was a reported case of an American who caught polio in Iceland in about 1955. His return home was followed by an outbreak of ME in his local community. It might have been a coincidence. EDIT Steigman AJ HartRH AdamsonJR Epidemic Neuromyasthenia N Engl J Med 1969:281: 797-798

This comment by Acheson is interesting: "What then is the link between this article (the 1959 one) and the present monograph? The key lies in the "protracted debility" which was a feature of a minority of patients in almost all the outbreaks and which persisted for months and, in a few cases...

The feeling that I have about this is that there are quite a few of us here who started out with an illness very like the Ramsay defined ME, but whose illness has morphed, over the years, into something rather different. There are others, equally ill, whose illness followed a different course...

www.ncbi.nlm.nih.gov/pmc/articles/PMC2425322/?page=1 This paper by Parish describes the phenomenon at p713

This is the ME- pedia link about it but I think Ramsay said more in his book, which I no longer have. I shall see what I can find. I think Acheson may also have mentioned it. http://me-pedia.org/wiki/1948-49_Akureyri_outbreak

Do you have any comment to make on the Iceland ME "epidemic" which appeared to confer upon those in the affected area immunity from polio in a later epidemic of that disease. That appears to have been an important driver for the supposed polio association.