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  1. Mij

    UK - Anyone know what the DWP/Capita etc are told about ME/CFS? assessors Decision MAkers

    Yes but 'brain fog' is not very descriptive. It's a general term. My sister has Hashimoto and says she has 'brain fog' when she eats certain foods. I use the term cognitive impairment which describes having difficulty concentrating/remembering, learning new things and making decisions...
  2. Mij

    Storing excess ATP molecules helps cells to avoid protein aggregation

    Budding yeast cells with high levels of ATP do not lead to abnormal aggregation of proteins (magenta), while mutant cells with low levels of ATP exhibit clumps of proteins (magenta). Taken together, Takaine et al.’s results suggest that ATP plays a role in stopping proteins from sticking...
  3. Mij

    High and stable ATP levels prevent aberrant intracellular protein aggregation in yeast, 2022, Masak Takaine et al

    Abstract Adenosine triphosphate (ATP) at millimolar levels has recently been implicated in the solubilization of cellular proteins. However, the significance of this high ATP level under physiological conditions and the mechanisms that maintain ATP remain unclear. We herein demonstrated that...
  4. Mij

    Mpox, formerly called Monkeypox

    https://www.mass.gov/news/massachusetts-public-health-officials-confirm-case-of-monkeypox https://www.statnews.com/2022/05/18/spain-portugal-report-monkeypox-cases-raising-specter-of-wider-outbreak/
  5. Mij

    Aromatherapy blend of thyme, orange, clove bud, and frankincense boosts energy levels in post-COVID-19 female patients..., Hawkins et al, 2022

    I inhaled a clove cigarette in the early 80s and my head raced. Cloves(eugenol) and help clear respiratory disorders.
  6. Mij

    Short-Term Magnesium Therapy Alleviates Moderate Stress in Patients with FM: A Randomized Double-Blind Clinical Trial, 2022, Nicolas Macian et al

    The formulation was ChronoMag in the study I posted. https://pubmed.ncbi.nlm.nih.gov/29524192/ Abstract While general recommendations are for 300-mg magnesium intake a day, an advanced low-dose formulation of magnesium chloride, ChronoMag®, was designed to provide 100 mg of magnesium...
  7. Mij

    Short-Term Magnesium Therapy Alleviates Moderate Stress in Patients with FM: A Randomized Double-Blind Clinical Trial, 2022, Nicolas Macian et al

    Abstract Patients suffering from fibromyalgia often report stress and pain, with both often refractory to usual drug treatment. Magnesium supplementation seems to improve fibromyalgia symptoms, but the level of evidence is still poor. This study is a randomized, controlled, double-blind trial...
  8. Mij

    Question: what do you think is a reasonable time that passes between an infection and ME/CFS onset?

    Sudden viral onset-->6 months was able to go to school and do some exercise (no PEM) but losing stamina-->'recovered' after 3 months, went back to work-->relapsed less than one month later--> was still able to do some light exercise without delayed typical PEM. My guess is that M.E was...
  9. Mij

    Thirty-Day Post-Discharge Outcomes Following COVID-19 Infection, 2022, Justin R Kingerly et al

    Abstract Background The clinical course of COVID-19 includes multiple disease phases. Data describing post-hospital discharge outcomes may provide insight into disease course. Studies describing post-hospitalization outcomes of adults following COVID-19 infection are limited to electronic...
  10. Mij

    Dr Alain Moreau video - developing new test to discriminate between ME & Fibro

    Their study aims to investigate circulating microRNA expression in ME/CFS patients before and after a stress challenge that stimulates PEM. The findings highlight the differential expression of eleven microRNAs associated with a physiological response to PEM. I've never experienced pain in 31...
  11. Mij

    Dr Alain Moreau video - developing new test to discriminate between ME & Fibro

    Every FM friend that I've met irl do not experience PEM, and have no clue what I'm talking about when I describe my experience with PEM.
  12. Mij

    Shortage of Cellular ATP as a Cause of Diseases and Strategies to Enhance ATP, 2019, Todd A Johnson et al

    Germline mutations in cellular-energy associated genes have been shown to lead to various monogenic disorders. Notably, mitochondrial disorders often impact skeletal muscle, brain, liver, heart, and kidneys, which are the body’s top energy-consuming organs. However, energy-related dysfunctions...
  13. Mij

    UK Equality and Human Rights Commission - are ME/CFS and Long Covid classed as disabilities?

    I was automatically denied Federal disability benefits when I first applied in 1992. The judicator concluded that I was still capable of 'gainful employment", so I decided to call the Ministry of Health and spoke to the judicator who reviewed and denied my claim to ask how she came to her...
  14. Mij

    News from Canada

    The SARS outbreak was almost 20 years ago, but at least they're interested in learning more. Perhaps even go back 70 years and find out that M.E wasn't a mid-century campfire story after all?
  15. Mij

    Circadian rhythm disruption in [ME/CFS]: Implications for the post-acute sequelae of COVID-19, 2022, McCarthy

    The lab tech hooked me up with electrodes and told me to sleep, but when I explained that I needed to take trazodone in order to fall asleep, she told me to 'try to sleep' w/o it. I told her I can not fall asleep at all w/o the meds. She left the room and I stayed awake until 2 a.m, so...
  16. Mij

    Long Covid in the media and social media 2022

    Imagine telling a cardiologist and pulmonologist that you're still suffering from a litany of symptoms, including exhaustion, shortness of breath, headaches, joint pain et and they both rule out other health problems and advise exercising, suggesting that some symptoms may have been a result...
  17. Mij

    Long Covid in the media and social media 2022

    Just watched the CBC (Canada) news this morning and PHAC (Public Health Agency of Canada) are studying how many Canadians have long-Covid. They've stated that there are over 100 symptoms, 'mostly fatigue, anxiety and PTSD". I can see where this is going.
  18. Mij

    Development and testing of new vaccines against EBV and other viruses

    Moved post NIH Launches Clinical Trial of Epstein-Barr-Virus Vaccine The study will enroll 40 healthy volunteer adults ages 18 to 29 years, half of whom have evidence of prior EBV infection and half of whom do not have evidence of prior EBV infection. Participants will be given a series of...
  19. Mij

    Fatigue measurement scales

    https://journals.sagepub.com/doi/10.1177/1352458520941481 The problems of inaccurate terminology The much-identified impasse in defining daily onset MS-related tiredness appears—in the absence of an accurate label—to derive from the appropriation of the inaccurate nomenclature “fatigue.” In...
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