Search results

Abstract Importance Aging is associated with a decline in mitochondrial function and reduced exercise capacity. Urolithin A is a natural gut microbiome–derived food metabolite that has been shown to stimulate mitophagy and improve muscle function in older animals and to induce mitochondrial...

No, because I talk to myself and I would have noticed.

I took off my mask the other day because I couldn't hear the tv. Is that BF, an M.E moment or something else?

I think there are different experiences in what some describe as brain fog. My delayed cognitive impairment feels like an energy deficit. I slur and have difficulty processing information when my brain is over loaded with simple tasks. I don't have memory issues I need to lie down...

"When it comes over me, I feel like the only thing inside my skull is polystyrene" That's a new one to describe brain fog, and yes I had to google polystyrene.

I would like to know what is causing the underlying deficiencies. It can't all be caused from malabsorption? My test panels indicated countless deficiencies.

I find it interesting that parkinsonian-like syndrome is referred to as manganism. I would humbly advise not to take Mn, or at least not a high dosage. Mn toxicity seems to accelerate neurotoxicity from what I've read. I had parkinsonian-like-syndrome back in 2000 and took mg/taurine...

Reactivation of EBV and HHV6 brought on OI/autonomic impairment 10 years after having M.E.

Abstract Epstein-Barr virus (EBV) reactivation has been proposed as a driver of Long COVID (LC), but studies in well-characterized post-acute COVID-19 cohorts of individuals with and without Long COVID symptoms over a time course consistent with current case definitions of LC are limited. In a...

Background: Either high or low values of adenosine blood level (ABL) can differentiate some forms of neurally mediated syncope (NMS). A rapid method of measurement has recently been developed. The aim of the present study was: (1) to compare ABLs in an unselected population of consecutive...

@Wonko, yes CoQ10

I have low citric-acid cycle intermediates. Most important cofactors of this cycle are: iron, copper and OOQ10. A deficiency of the any of following factors may support the block of the citric acid cycle. Vitamin B1, B2, B3, lipoic acid, pantothenic , maganese and magnesium. Increasing...

They have trying to get funding from NIH for the maganese and copper w/o success RD: "Maganese needs to be digested and transported from the gut-->blood-->cell-->mitochondria. It can get blocked at any one of these levels. It's got to get into the mitochondria in order for it be functioning...

Preprint Abstract Importance: Reduced exercise capacity is commonly reported among individuals with Long COVID (LC). Cardiopulmonary exercise testing (CPET) is the gold-standard to measure exercise capacity to identify causes of exertional intolerance. Objectives: To estimate the effect of...

I wonder how this therapeutic will positively affect the brain.

I need meat protein. I've tried a macrobiotic diet for six weeks, but felt much better when I went back to eating meat again.

I'm wondering if temperatures for this type of therapy have to be that freezing cold in order to have positive benefits? Most ppl with autonomic issues feel better in cooler/colder temperatures.

I live in eastern Canada and a brisk 5 minute walk in mid January could render the same effects?

Could it have something to do with leptin resistance? I read something about this years ago.

What's new is old and what's old is new. That's the history of M.E as it stands.