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Iwasaki was also very recently asked about microclots since her team are investigating them as well . I thought her opinion would be a decent reflection of their current research as she has a better tone than some of the “Twitter scientists”. The gist of it (or my interpretation of it) is that...

That I don't know, but I certainly would like to know how this data matches with that of Phair/Davis/Armstrong. My phrasing wasn't good, what I want to say is that Phair's and Davis' own measurements didn't corroborate their own theories (I think the Kynurenine trial was particularly dissapointing).

From what I’ve understood the IDO2, Kynurenine and Tryptophan measurements didn’t corroborate Davis & Phair’s theories. Was anything published or is the data available somewhere? The researchers of this paper are also ME/CFS researchers.

Prolonged indoleamine 2,3-dioxygenase-2 activity and associated cellular stress in post-acute sequelae of SARS-CoV-2 infection Background Post-acute sequela of SARS-CoV-2 infection (PASC) encompass fatigue, post-exertional malaise and cognitive problems. The abundant expression of the...

I also don’t have access to it, but I always find it is a bit strange to write about a topic your colleagues next door have and currently are doing research on, without supposedly even reaching out to them or even being aware of their work.

I believe that there's reason to hope that these studies will indeed be better (and provide evidence in either direction) in particular as they are looking at evidence in vivo, rather than just handpicking some biased 2D measures of 3D objects in test tubes, which could be an artefact of...

These studies are currently happening, perhaps it would have been more useful to wait for these new results. Iwasaki, Putrino, Rob Wüst, VanElzakker, Dupont, Dalton and others are currently all conduction microclot studies. So they were at least convinced by the evidence they've seen to quickly...

I think the message of the review is relatively sound. But their conclusion is really just what everybody on social media and doctors have been saying for the past 2 years as well. It would have been far more useful to actually do a study to see what role these clots play, either proving its...

Long-Term Dysfunction of Taste Papillae in SARS-CoV-2 BACKGROUND We sought to determine whether ongoing taste disturbance in the postacute sequelae of coronavirus disease 2019 period is associated with persistent virus in primary taste tissue. METHODS We performed fungiform papillae biopsies...

Plasmapheresis to remove amyloid fibrin(ogen) particles for treating the post‐COVID‐19 condition Background The post‐COVID‐19 condition (PCC) consists of a wide array of symptoms including fatigue and impaired daily living. People seek a wide variety of approaches to help them recover. A...

Both Polybio https://polybio.org/projects/sars-cov-2-gut-persistence-intestinal-permeability-and-spike-protein-in-pediatric-long-covid-mis-c/ and RECOVER https://classic.clinicaltrials.gov/ct2/show/NCT04588363 seem to be studying MIS-C as well, so there should be more studies on this coming out...

Cortical thickness alterations and systemic inflammation define long-COVID patients with cognitive impairment Abstract As the heterogeneity of symptoms is increasingly recognized among long-COVID patients, it appears highly relevant to study potential pathophysiological differences along the...

The Mirror and the Independent have also reported on it. https://www.independent.co.uk/news/health/long-covid-brain-fog-research-b2379570.html https://www.mirror.co.uk/news/health/brits-long-covid-symptoms-age-30521234 This study is certainly gaining some media attention online. I hope it'll...

I don't think that'll be possible since Rob Wüst's findings haven't been published (the article is about a different study). It's more of a question for those that have knowledge of such biopsies without being able to read the study.

This is also what I'd be interested in. Can these dust looking like microclots and similar problems still occur in these muscle biopsies if one is looking inside of skeletal muscles?

Myopathy as a cause of Long COVID fatigue: Evidence from quantitative and single fiber EMG and muscle histopathology Highlights Myopathic changes in qEMG and/or increased jitter in sfEMG were seen in 63% of 84 patients with Long COVID neuromuscularsymptoms. Low quality of life score correlated...

A comment on this paper published in science: https://www.science.org/content/article/one-five-people-who-contract-covid-19-virus-don-t-get-sick-gene-variant-may-explain-why.

A common allele of HLA is associated with asymptomatic SARS-CoV-2 infection Abstract Studies have demonstrated that at least 20% of individuals infected with SARS-CoV-2 remain asymptomatic1,2,3,4. Although most global efforts have focused on severe illness in COVID-19, examining asymptomatic...

Highlights A group of trials with trust concerns had major impacts on the results of systematic reviews and clinical guidelines. They substantially impacted effect sizes and influenced the conclusions and recommendations drawn. There is a need for a greater focus on the trustworthiness of...

Link to published version here Preprint Abstract To understand the roles of acute phase viral dynamics and host immune responses in PASC, we enrolled 136 participants within 5 days of their first positive SARS-CoV-2 real-time PCR. Participants self-collected nasal specimens up to 21 times...