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  1. rvallee

    What needs to change to ensure better care for people with ME/CFS with feeding difficulties?

    This ties in to what I just wrote about psychosomatic ideology being fundamentally dishonest. It's a slightly different aspect of it but it amplifies the problem of deliberate deceit: the very concepts lack internal consistency. Applying a concept that has no internal consistency means throwing...
  2. rvallee

    What needs to change to ensure better care for people with ME/CFS with feeding difficulties?

    At its core is a problem of fundamentally dishonest misrepresentation. It was critical with Maeve. Decisions were made about her based on decision-making that was dishonestly kept secret with the knowledge that it can't be justified. PwME are asked to put trust into systems and people who have...
  3. rvallee

    Review The effect of graded exercise therapy on fatigue in people with serious respiratory illness: a systematic review, 2024, Angela T. Burge et al

    As is usually the case, where they argue that there is a significant effect, it's the least significant possible using minimally important differences that are very low. I'm not sure what a sensitivity analysis involves, but for the primary outcome of fatigue, the minimal important difference is...
  4. rvallee

    Changes in thalamic functional connectivity in post-Covid patients with and without fatigue, 2024, Manuel et al.

    Going to have to work extra hard to avoid the inevitable confusion with the other meaning of function here. Which is obviously why they chose it. There will be so much unnecessary confusion if this turns out to be important, and it looks more and more like it, with neurons and other brain cells...
  5. rvallee

    Brain Retraining treatment for ME/CFS and Long COVID - discussion thread

    In the first year, up to the 2nd, of Long Covid, patient forums were filled with people detailing their supplement stacks and regimens and whatnot, attributing their recovery to this or that combination of supplements plus this change of diet plus some change in mindset or lifestyle plus plus...
  6. rvallee

    STING recognition of viral dsDNA by nociceptors mediates pain in mice, 2024, Berta et al

    This might be relevant to chronic illness in general, but also specifically to us. We often have discussions here over the role of inflammation, what counts as inflammation and how symptoms typical of inflammation can be explained when its typical signs can't be detected. But it turns out that...
  7. rvallee

    STING recognition of viral dsDNA by nociceptors mediates pain in mice, 2024, Berta et al

    STING recognition of viral dsDNA by nociceptors mediates pain in mice https://www.sciencedirect.com/science/article/pii/S0889159124004823 Highlights Nociceptors can directly sense viral nucleic acids, such as dsDNA derived from herpes and vaccinia viruses. Cytosolic dsDNA causes nocifensive...
  8. rvallee

    News from Canada

    The ICanCME network has been funded for another 5 years, with $2M CAD from CIHR-IMHA. Unsure whether this matters much given that we have seen nothing from it, but given the people involved, it is better that this gets renewed than not. We haven't seen much from the NIH's funding either. The...
  9. rvallee

    Miranda Hart - British comedian

    Like voodoo but without the totems. Which makes it even more laughable, but it's considered cutting edge medical science. Humans are soooo freaking weird. Either we are the weirdest species in the galaxy, which, wow. Or there are even weirder species out there, which, WOW!
  10. rvallee

    What needs to change to ensure better care for people with ME/CFS with feeding difficulties?

    In the discussion over sectioning is missing the crucial part: what then? What would have been done to Maeve had she been sectioned? I don't think this can be discussed without those facts, and for certain there is an answer to this question, it's just one made in secret behind closed doors with...
  11. rvallee

    Chronic Overlapping Pain Conditions in people with [ME/CFS]: a sample from the Multi-site Clinical Assessment of ME/CFS (MCAM) study, 2024, Fall et al

    Holy crap people it's literally called MYALGIC, meaning muscle pain. That the pain originates from muscles is unlikely to be accurate but pain is obviously part of the illness and of most criteria, as long as one doesn't rely on useless criteria like Sharpe's Oxford criteria. This is not some...
  12. rvallee

    Effects of psychological interventions on clinical outcomes in patients with cardiovascular diseases: A systematic review and meta-analysis, 2024

    The conclusions don't follow the data, about the same as with most of the psychological rehabilitation evidence base for physical illnesses. Big claims in the highlights about lower cardiac mortality and adverse effects, but only out of pooled results with trivial effects that are likely noise...
  13. rvallee

    Effects of psychological interventions on clinical outcomes in patients with cardiovascular diseases: A systematic review and meta-analysis, 2024

    Effects of psychological interventions on clinical outcomes in patients with cardiovascular diseases: A systematic review and meta-analysis https://www.sciencedirect.com/science/article/abs/pii/S0022399924003507 Results A total of 32 studies were included, involving 15,814 patients. Our results...
  14. rvallee

    Maeve Boothby O'Neill - articles about her life, death and inquest

    The legal aid fund rejecting aid on the basis that there is no systemic failing and no public interest would be too ham-fisted even for most legal drama. It belongs more in a bad Western drama where the accused is the sheriff and the judge and all his buddies make up the jury. Especially...
  15. rvallee

    Media items about obesity

    Ironic considering that most only really do fitness coaching. You'd think they would actually see this as some sort of positive, two birds with one stone and all. But of course the whole thing is a sham so they don't actually follow through with the premise of what they do. Really says a lot...
  16. rvallee

    News from Canada

    Definitely not why they suck, though. They suck because they're the Leafs. :laugh: Ironically Tavares has been promoting some weird amulet that wards off illnesses and radiation, or whatever. I guess it doesn't work.
  17. rvallee

    An open letter regarding Scientific Reports

    To point out problems in academia while praising a body of work literally built out of the worst offenses for those problems is basically like the root cause of the problem looking at its consequences. Follows the usual "this research is bad" = I don't like it. Richard Horton said that in his...
  18. rvallee

    UK:ME Association funds research for a new clinical assessment toolkit in NHS ME/CFS specialist services, 2023

    I doubt that any accountant worth their salt would find performative box-ticking valuable exercise. They know better, because they count things, and here it's basically no pluses and lots of minuses. A competent accountant would definitely not find this valuable. Well, all they'd do is report...
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