Search results

I think there are several threads discussing this topic. Not sure which one is the most appropriate. A members-only thread that includes somewhat related discussions on this topic but with another focus is here: https://www.s4me.info/threads/non-e...omedical-and-psychological-me-research.18266/

Perhaps we need to differentiate the target audience regarding this issue. What might be a good response to family and friends, might be an unfortunate feeding of a harmful narrative when stated in a conversation with a doctor (depends on the doctor) or in a public debate -- the wider the...

Edzard Ernst added a short comment on his blog article on the Lightning Process from last year: "the ‘study’ hardly deserves any discussion; no control group!" https://edzardernst.com/2020/06/the-lightning-process-implausible-unproven-hyped-and-expensive/#comment-133138...

The new NICE Guideline for ME/CFS: Ten Questions Answered - The Science Bit https://thesciencebit.net/2021/08/15/the-new-nice-guideline-for-me-cfs-ten-questions-answered/ Haven't read it yet but this looks very good. Thank you, @Brian Hughes.

:eek: A reason why peer reviewers should always look at the references.

I also hope that people are working on that already. Anyway, these are some questions that I likely would have asked if I were a journalist or an other observer new to the topic: 1) Was the evaluation of the benefits of treatment options done equally sound as before and as it is done with...

Park this here for adding it to the OP later. Harrison, A. M., das Nair, R., & Moss-Morris, R. (2016). Operationalising cognitive fatigability in multiple sclerosis: A Gordian knot that can be cut? Multiple Sclerosis Journal, 23(13), 1682–1696. doi:10.1177/1352458516681862...

Anyway, the paper contains a potentially useful "Summary of measures of cognitive fatigability operationalised in existing research" on MS (table 1, p.2-11).

Only skimmed the paper but the conclusion caught my eye: Conclusion: "Future research may benefit from (a) developing a guiding theory of cognitive fatigability, (b) examining ecological and construct validity of existing assessments and (c) exploring whether the more promising cognitive...

Harrison, A. M., das Nair, R., & Moss-Morris, R. (2016). Operationalising cognitive fatigability in multiple sclerosis: A Gordian knot that can be cut? Multiple Sclerosis Journal, 23(13), 1682–1696. doi:10.1177/1352458516681862 sci-hub.se/10.1177/1352458516681862 Abstract Background...

quote: "The draft from November calls for a radical change in the treatment strategy, which has caused a furore among some clinicians and professionals in the field. They have criticized the change for not being adopted on a scientific basis. Conversely, the draft has aroused great joy among...

Via e-mail: Daily Digest: Chat to NICE ME/CFS guideline committee members (There are only 100 spaces to attend so register now!) After too many years of waiting, the final version of the new ME/CFS guideline developed by NICE will be published on the 18th August 2021! On Tuesday 24th August...

Thanks for your offer @FMMM1 . Luckily, I got very helpful answers from S4ME members. Many thanks to everyone.

Yesterday I posted here a question about Brian Hughes' blog article on the history of the review of evidence on ME/CFS commissioned by NICE. I deleted the post after I had received a reply from Brian Hughes. He gave me the permission to share his reply here:

wouldn't it be good if someone of the best critics of the usual suspects had access to the SMC briefings?

Can't be repeated too often. (All 3 paragraphs) Huge thanks from me, too.

If anyone wants to check the JAMA paper from 2001: Whiting P, Bagnall A, Sowden AJ, Cornell JE, Mulrow CD, Ramírez G. Interventions for the Treatment and Management of Chronic Fatigue Syndrome: A Systematic Review. JAMA. 2001;286(11):1360–1368. doi:10.1001/jama.286.11.1360...

Cochrane though use GRADE too, and repeatedly came to different conclusions in their assessment of the quality of evidence of therapist-delivered treatments. Also, didn't NICE use GRADE for their cr*p Guideline on "primary pain"? I think that point needs to be addressed -- see post above...

Indeed. I wasn't aware of that part of NICE's history. Thank you @Brian Hughes . I hope it's OK to quote a bit more from Brian Hughes' article. About the old (2007) NICE guidelines' evaluation of the then small evidence base: Edited for clarity.

Of course, the usual suspects will have an armada of eminent 'experts' who will try to defend their CBT-and-exercise-always-helps-especially-in-functional-illness-narrative, mixed with narratives along the lines of 'no trial is perfect' and 'if blinding is not possible in clinical trials, we...