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  1. Jonathan Edwards

    Can vaccines cure ME/CFS or Long Covid?

    As an immunologist, I had never actually heard of 'trained immunity'. Maybe it's a Twitter thing?
  2. Jonathan Edwards

    UK: Action for ME: Media Guidelines for reporting on M.E.

    From what I have seen I agree that this is better than before and not bad. BUT it does seem very amateur and full of suboptimal statements. Why is this so, when if S4ME had been asked to produce a document I am pretty sure it would have been professional and got the detail right?
  3. Jonathan Edwards

    UK clinic: Harley Therapy

    In the last week or two we have heard of AI machines that can produce stuff that sounds almost as if it was written by a human. Today we discover that there are humans that can produce stuff that sounds almost as if it were written by a bot - but not quite that good.
  4. Jonathan Edwards

    The micro-clot finding in Long Covid — implications for the possible aetiology of ME/CFS

    Depends a bit on the quality of the magic I guess. One thing I note was that people either showed improvement or 'no effect'. But since they were likely to have improved anyway maybe improvement is 'no effect'. And 'no effect' really means failure to improve or worse - quite likely a bad effect.
  5. Jonathan Edwards

    Scientists identify reversible molecular defect underlying rheumatoid arthritis

    Maybe Dr Vousden has not read the literature that shows that almost complete wiping out of T cells for a period of many years with a monoclonal antibody (CAMPATH 1H)had no useful effect on human rheumatoid arthritis. The problem with medical research these days is the complete ignorance about...
  6. Jonathan Edwards

    OpenAi's new ChatGPT

    There is something about the way brains and lymphocytes work that I have not seen discussed in computer systems. Both of them generate millions or billions of 'shapes' that are not digital, nor even analogue but I think multiple inflection-based. It is not so much topology as lock and key -...
  7. Jonathan Edwards

    The micro-clot finding in Long Covid — implications for the possible aetiology of ME/CFS

    The presentation is unprofessional in various respects. I find it hard to see the ethical justification for giving anticoagulants, which carry significant morbidity and mortality, in a trial that does not look as if it can give any useable results.
  8. Jonathan Edwards

    A general thread on the PACE trial!

    There are lots of political reasons for not being an author. I have been in that position. If one has been involved in getting a project set up in some other capacity or is expecting to act as referee or things like that. It suggests some potential conflict of interest. I have made decisions...
  9. Jonathan Edwards

    Independent advisory group for the full update of the Cochrane review on exercise therapy and ME/CFS (2020), led by Hilda Bastian

    With due respect, @Medfeb this seems a bit like asking the 'community' to make a formal enquiry into how Penelope is getting on with her shroud-weaving in Ithaca. The community have made it abundantly clear that they think this is a cop out of gigantic proportions and I suspect no sane person...
  10. Jonathan Edwards

    Well-known, famous people with Covid-19 and Long Covid

    Must be on that new channel, certainly not BBC.
  11. Jonathan Edwards

    Well-known, famous people with Covid-19 and Long Covid

    Who's this Garrawy lady anyway? (Moderators please delete if this is a Lineker moment, or maybe not. Ah, these hard decisions.)
  12. Jonathan Edwards

    Independent advisory group for the full update of the Cochrane review on exercise therapy and ME/CFS (2020), led by Hilda Bastian

    Except that we know that some definitely not-true-believers were involved - some we know well and respect. I can imagine that for a long time it would be difficult to whistleblow if only because of potential fall-out for PWME, but I get the feeling that now may be the time for people from...
  13. Jonathan Edwards

    Independent advisory group for the full update of the Cochrane review on exercise therapy and ME/CFS (2020), led by Hilda Bastian

    I actually think that this thing has been handled so unethically that it is time somebody blew the whistle. There must be someone on the project who can tell the world just how much Cochrane have sunk into hypocrisy. There can be nothing to be achieved by adhering to gagging clauses.
  14. Jonathan Edwards

    What has happened to NHS staff pay since 2010?

    One thing that I wondered about is whether there are rules about it only being legal to strike in one's own interest. In other words strikes can only be justified on the grounds of one's pay or conditions. From my own experience I would imagine that most health professionals would want to strike...
  15. Jonathan Edwards

    UK: Social prescribing on the NHS (and possible implications for ME/CFS services)

    A few years ago an editor pointed out to me that in my discussion of some quantum mechanical metaphysics I had written back-peddling when I meant back-pedalling. Seems to me you meant special-peddling, not special pleading!!
  16. Jonathan Edwards

    Endothelial dysfunction in ME/CFS patients, 2023, Sandvik, Mella, Fluge et al

    Thanks, my flagging system seems a bit arbitrary. I wouldn't think it was a bad option. Signals can be blocked either in nerve tissue or elsewhere. We are getting to the stage when almost any malfunction can potentially be corrected with genes or monoclonals or whatever.
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