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I didn't bother to read the full paper, but the abstract sounds like they came up with a bunch of excuses for why a lack of evidence supporting the hypothesis shouldn't be considered as a lack of evidence.

Wouldn't scoring on the test be affected by physical symptoms (concentrating less because you feel lousy) and changes in activities during the day (being less active due to feeling lousy) and changes in lifestyle (vegging out in front of TV rather than reading, crafting, etc)?

I did get worse symptoms from meat fats, which I thought was from palmitic acid (based on the responses to different foods). Carnitine blocked that. I wonder if it would affect their experiment cells too.

Yes, Moderna. I'm heading in for the shot today.

When I booked my second vaccine appointment, I was offered either a second dose of the Pfizer vaccine, or a dose of the other one (starts with an 'M'), which is supposed to be just as effective. I did ponder whether ME might cause problems with a different vaccine or with a second dose of the...

Desperation? No, the psychiatrists would probably come up with a fancier and even less meaningful term.

It would be interesting to compare those with a modern sampling of typical underexercised poor diet subjects. :)

Going by the photo, '10 degrees cooler' is due to being more reflective than wood that's painted red or green (fairly poor solar reflectivity). What I'd want to know is the temperature difference between his paper and white paint (regular or designed for solar reflectivity). My guess is that...

So, did they come up with a clear, concise, quantifiable (and verifiable) definition of insomnia that everyone studying insomnia can agree to use?

I don't know of any actual studies, but I think it would be hard to prove that food sensitivities do not occur. Our bodies are amazingly complex in their biochemical interactions, so we all have different sensitivities to various chemicals. I was quite sensitive to nightshade toxins (potatoes...

The triggering and recovery of PEM would have different subsets, but the point is to discover the mechanism of PEM: whatever it is that changes as the result of triggering. That is likely to be the same for most PWME and maybe long-covid. Even if the reliable, consistent PEM subset was small...

Does anyone know whether long-covid PEM is consistent? Many PWME can reliably trigger PEM and have it show up a consistent x hrs after the exertion and have it last a consistent x hrs after it shows up. If so, then maybe we can get long-covid researchers, with their better funding, to do the...

I do believe that my ME involves abnormalities in my kynurenine pathway. Too much QUIN would probably explain some (most) of my symptoms. I think niacin made me feel worse because without dietary intake of it, my enzymes would convert more of the excess QUIN into niacin.

I'd rather see the research funding going towards figuring out what we all have in common, rather than studying downstream symptoms that only some PWME have. If resources were unlimited, sure, maybe it would lead to a treatment for a symptom faster than trying to find one that treats all ME...

Even that is probably only 'a large subset of PWME' rather than something all PWME have. I didn't notice any reduction in my physical capabilities after significant exertion. I'm guessing that I wouldn't show a reduction on a properly done CPET test.

Things found in old recipes, such as flours or grains or seeds. Over the years I've noticed several such things disappear from the shelves. It's not just foods. Ammonia used to be a common cleanser. I looked for some recently, and couldn't find any. Replaced by fancy brand-named cleansers.

One thing I've noticed is that it's getting hard to find basic foods. On my last trip, I wanted to try some lamb, and the store only had one package of chops and two larger cuts. I used to see frozen legs cut into chops, but couldn't find those now. I guess the space has been given over to...

My weight started to rise rapidly just before my ME developed (a link there?). My solution was to simply reduce my meal sizes. That worked really well, and I fairly quickly dropped back to my previous 'normal' weight, and continued to drop. I also learned that cutting too much fat from one's...

I've heard a lot of Canadians returning from trips to the US say that they were amazed at the size of American meals; much larger portions than served in Canadian restaurants. What's the caloric difference between a typical French meal and a typical US one?

I had slightly reduced 'good' cholesteral, so my doctor recommended omega-3 supplements or statins. I did my own online research and found that statins weren't all that effective (and had worrisome side-effects) and that omega-3's lacked any reliable research findings that indicated more than a...