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Maybe relevant: my dad and my dad's mom both had Parkinson's. I'm pretty sure I remember that my dad (not sure about my grandma) had loss of smell. I have ME (not caused by COVID) and loss of smell.

α-synuclein Seeding Activity in the Olfactory Mucosa in COVID-19 Medical University of Innsbruck Innsbruck, Austria Estimated study completion: 2023-12-31 Brief Summary Loss of the sense of smell is a characteristic feature of COVID-19 and likely related to viral invasion of the olfactory...

Ah ok, I'm still not quite fully versed in how VAT is calculated, but if this is true, I'm less worried.

She also claims to make £50,000 per month from admiring fans even though she no longer works. I'm sure that helps with the "incredible lifestyle". Maybe I'm in the wrong line of work.

This feels kind of weird to me: "ME/CFS participants who met maximum effort criteria during test 1 but did not meet criteria during test 2 due to failure to achieve heart rate and/or RER criteria were not excluded from analysis. ME/CFS who did not meet heart rate or RER criteria during test 2...

Not sure how "famous" she is but: Mirror.co.uk: Model and mum battles condition it took seven years to diagnose "Char Borley, who has appeared on the covers of Playboy and FHM, has been privately contending with a serious health struggle. The 41-year-old Suffolk native has now been diagnosed...

Science Norway: Victoria Augustine falls ill from everyday activities like taking a shower or family visits: “I end up bedridden with a feverish feeling and body aches" By Ingrid Spilde "Victoria Augustine Trulsen, 25, can remember the first time she thought: This can't be normal. She had been...

Just want to note this: "Competing interests BK, CR, JS, and SS conduct 2-day cardiopulmonary exercise testing on a fee for service basis."

Nice! Added. This looks like a pretty good comparison if their claim is true that performance on CPET-1 is a good indicator of activity level. See Figure 5B below for an impressive looking result. "Figures 5A–C illustrate the similarity between phenotypes in impairment status at baseline...

Now published, see post #8 ------------------------------------------- Circulating microclots are structurally associated with Neutrophil Extracellular Traps and their amounts are strongly elevated in long COVID patients Etheresia Pretorius¹, Alain THIERRY², Cynthia Sanchez³, Tram Ha⁴, Brice...

ScienceAlert: COVID's Hidden Toll: Full-Body Scans Reveal Long-Term Immune Effects By Carly Cassella "When 24 patients who had recovered from COVID-19 had their whole bodies scanned by a PET (positron emission tomography) imaging test, their insides lit up like Christmas trees. A radioactive...

Looks like very good separation between acute/long COVID and the other groups: Would be nice to see healthy controls included in the future.

AI generated summary of Tim Henrich's talk that Amy linked to: Introduction The speaker is continuing a discussion on molecular imaging and digital spatial profiling in long COVID The talk aims to highlight the promise of immunotherapy clinical trials This presentation is part of the larger...

Looks like there's a thread about that drug.

I can't access the actual paper, but the figures are available to view in a PDF linked on the page above. Figure S4. Differences in [18F]F-AraG SUVmean uptake in certain tissues were observed when grouped by time from initial COVID-19 symptom onset to PET imaging and by Long COVID symptoms...

Merged thread Now published Tissue-based T cell activation and viral RNA persist for up to 2 years after SARS-CoV-2 infection Authors (formatted by AI): Editor’s summary The term “Long Covid” covers a diverse array of symptoms that an individual might experience weeks to years after...

Ah ok, my mistake, thanks.

I would add the search for a viral reservoir. Labs like PolyBio have lots of ideas for studies, and more money would surely speed trials along, for example with the expensive equipment necessary for specialized scans.

Isn't there an issue of scientists avoiding even entering the field because of lack of research funds? Where they don't want to devote their life to something where every grant will be rejected?