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  1. forestglip

    National Autistic Society says media reports on an autism cure study are ‘deeply insulting’

    Aren't there people with severe autism who can barely function? Who are immensely suffering? Would they not want their autism to be "cured" or "reversed"? ---- Controversies in Autism on Wikipedia: "There are two major conceptualizations of autism within autism advocacy. Those who favour the...
  2. forestglip

    Idiopathic chronic fatigue (non-ME)

    Epidemiology of ICF from Wikipedia: "Fatigue is common in the general population and often caused by overwork, too much activity or a specific illness or disease. Around 20% of patients who visit their clinician report fatigue.[1] Prolonged fatigue is fatigue that persists for more than a...
  3. forestglip

    Idiopathic chronic fatigue (non-ME)

    I thought there should be a thread to discuss chronic fatigue without the other symptoms of ME, but which has no apparent cause. How prevalent is this? How many people are bedbound with severe fatigue, having to hear people say they are depressed or lazy because all their blood work is fine...
  4. forestglip

    Do you believe that “viral persistence” is the cause of ongoing MECFS and LC?

    I emailed Nancy Klimas about this "exertion causes viral replication causes PEM symptoms hypothesis", and her response: "Also in exercise the immune system activates, which could trigger viral expression as well. We all focus on herpes family viruses but not nearly enough on the rest. New...
  5. forestglip

    Protocol Investigating the Feasibility of Repurposing HIV Antivirals in Adults With Long Covid [tenofovir/emtricitabine or maraviroc]

    Oh right, twice a day. That is a challenge. Maybe they can make everyone take two capsules a day, for Truvada one would be placebo. Though a curious participant probably wouldn't have a hard time figuring out the capsules are different.
  6. forestglip

    Protocol Investigating the Feasibility of Repurposing HIV Antivirals in Adults With Long Covid [tenofovir/emtricitabine or maraviroc]

    Inclusion criteria requires PEM (assessed with DePaul PEM questionnaire) ----- Inclusion Criteria: Exclusion Criteria:
  7. forestglip

    Protocol Investigating the Feasibility of Repurposing HIV Antivirals in Adults With Long Covid [tenofovir/emtricitabine or maraviroc]

    Can't they just make a bigger capsule with inert filler for the smaller dosage? (Just guessing, no idea if that is common practice.)
  8. forestglip

    Protocol Investigating the Feasibility of Repurposing HIV Antivirals in Adults With Long Covid [tenofovir/emtricitabine or maraviroc]

    Brief Summary The trial will test if two repurposed HIV antivirals can reduce symptom burden in adult participants with Long Covid compared to placebo. Viral infection and viral reactivation have been documented in Long Covid. Participants will be randomly allocated to receive antivirals, TDF...
  9. forestglip

    The recombinant shingles vaccine is associated with lower risk of dementia, 2024, Dercon et al

    The recombinant shingles vaccine is associated with lower risk of dementia Quentin Dercon, John A. Todd, John A. Todd, Paul J. Harrison Published: 25 July 2024 Abstract There is emerging evidence that the live herpes zoster (shingles) vaccine might protect against dementia. However, the...
  10. forestglip

    USA: NIH National Institutes of Health news - latest ME/CFS webinar 14 Jan 2025

    That's awesome, well done! Edit: I hope next time they don't make the timer enormous and the video feeds tiny again.
  11. forestglip

    USA: NIH National Institutes of Health news - latest ME/CFS webinar 14 Jan 2025

    Available to watch now: https://videocast.nih.gov/watch=54978 @Cybergreen91 spoke at 59:03, here is a transcript: "My name is Scott Daniska, and I have experience both as a patient and a researcher. I've conducted research through academia, industry, and government programs, as well as seen...
  12. forestglip

    Closed UK: DecodeME updates, was recruitment thread.

    I'm not sure if there are some preliminary results planned to be released, but they pushed study completion back a year to August 2025. From their FAQ: "DecodeME will now be completed before August of 2025 – the results will be released as soon as possible before this date." Blog with details...
  13. forestglip

    [Myalgic encephalomyelitis : etiopathogenesis, diagnosis and treatment], 2024, Scherrer et al

    [Myalgic encephalomyelitis : etiopathogenesis, diagnosis and treatment] (Full article in French) Robin Scherrer, Marian Galovic, Markus Gschwind, Octavia Sabin Published 17 July 2024 Abstract Myalgic encephalomyelitis (ME), also known as chronic fatigue syndrome (CFS), is a neurological...
  14. forestglip

    New-onset Parkinsonism as a Covid-19 infection sequela: A systematic review and meta-analysis, 2022, Ali et al

    New-onset Parkinsonism as a Covid-19 infection sequela: A systematic review and meta-analysis Published online 8 Aug 2022 Syed Sami Ali, Afshan Mumtaz, Mohammad Aadil Qamar, Sameer Saleem Tebha, Azma Parhin, Mehwish Butt, Mohammad Yasir Essare Background There remains a scarcity of literature...
  15. forestglip

    Visual media for learning biology/medicine

    One thing is that animations are amazing for helping me quickly and easily understand and remember things. If I can get a visual of a little T-cell bouncing around, doing whatever it does and showing how it interacts with other cells (little faces on the cells welcome but not necessary), that...
  16. forestglip

    Visual media for learning biology/medicine

    Thanks! I just signed up for that coursera course. I was worried because it was saying at least $50 to take it, but looks like it's free if you don't want a certificate.
  17. forestglip

    Visual media for learning biology/medicine

    For better or worse, the Ninja Nerd channel replied about ME/CFS: "Thanks so much for reaching out to Ninja Nerd. We completely agree with you! We are hoping to address these topics in our updated Neurology section. We plan on releasing this in the coming months. Thanks and we wish you all the...
  18. forestglip

    [...] LC-MS/MS analysis of ME/CFS plasma reveals dysregulated coagulation [...], endothelial dysfunction, [...], 2024, Nunes, Kell, Pretorius et al

    Yeah, looks like a typo. That term doesn't appear in the paper or in Google (except one result that also looks like a typo).
  19. forestglip

    Visual media for learning biology/medicine

    Is there any visual media you'd recommend? I was originally looking to try to understand the basics of the immune system - T-cells, B-cells, NK, etc. And I'm interested in digging into the mitochondrial energy cycles as well.
  20. forestglip

    Visual media for learning biology/medicine

    Yeah, was probably rash of me to request they cover ME. For me personally, this is about the limit of what my brain can handle. I've tried reading through textbooks, and can barely do a page a day at best.
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