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I think this data is from the UK biobank.

I found a post from a while ago on Phoenix Rising about a potential model of RNA virus-based PEM. They say that one of the stages that these viruses go through during replication is dsRNA (double stranded RNA), and that cells have a much harder time destroying the virus in this stage, versus...

A Brief Review of Cognitive Assessment in Neurotoxicology, 2011, Han et al Interesting that TMT-A is not correlated but TMT-B is.

Jarred Younger just released a followup video to this: AI generated summary: Introduction Dr. Younger presents new results from his laboratory Focus on how air quality may affect ME/CFS and fibromyalgia fatigue and pain Results are pending peer review and publication Study conducted by...

The meal replacement stage is only the first 8-12 weeks, then a 4-12 week transition into a full-food diet, which will be eaten the rest of the six months (~0-12 weeks). A counselor will help them maintain a healthy diet. And outcomes will be measured at 12 months.

Previous trial studying this intervention in diabetes: Primary care-led weight management for remission of type 2 diabetes (DiRECT): an open-label, cluster-randomised trial, 2017, Lean et al Link (The Lancet) [Paywall]

Registration page says the study ended on 31 May 2024, and they intend to publish on 1 November 2024.

Now published - link here ******************** The remote diet intervention to reduce Long COVID symptoms trial (ReDIRECT): protocol for a randomised controlled trial to determine the effectiveness and cost-effectiveness of a remotely delivered supported weight management programme for people...

Yes, according to the paper: From the first reference:

Full text as PDF

From above article: "Globally, [noncommunicable diseases] have become the most common cause of death and disability, and they are increasing in incidence, accounting for nearly 41 million deaths per year, with 77% occurring in [low and middle income countries] (7). Although age-standardized...

Toward cleaner air and better health: Current state, challenges, and priorities Wei Huang, Hongbing Xu, Jing Wu, Minghui Ren, Yang Ke, Jie Qiao Published 25 July 2024 Abstract The most up-to-date estimate of the global burden of disease indicates that ambient air pollution, including fine...

Maybe for drawing conclusions directly from the model output, but I think it could stay very valuable as a hypothesis generating tool. Even if 9 out of 10 outputs are incorrect, it still has the potential to unearth and focus in on treatments people are talking about in the corners of the...

Identification of SARS-CoV-2 Persistent Infectious Epithelial Syndrome (SPIES) as a Novel Disease Entity using Clinical, Histologic, and RNA Programmatic Data Thomas Wallach, Ahmed Soliman, John Agboola, Shagun Sharma, Lais Araujo Coelho, Meredith Pittman, Christos Chatzinakos, Sergios-Orestis...

Twitter thread from author One tweet: "NATURAL was also inspired by my journey with #LongCovid. We need more investment, more clinical trials, more attention. Can we accelerate this by using the experiences that patients are sharing on forums?"

End-To-End Causal Effect Estimation from Unstructured Natural Language Data Nikita Dhawan, Leonardo Cotta, Karen Ullrich, Rahul G. Krishnan, Chris J. Maddison Abstract Knowing the effect of an intervention is critical for human decision-making, but current approaches for causal effect...

NATURAL: End-To-End Causal Effect Estimation from Unstructured Natural Language Data "Does semaglutide protect kidney health? Do later school times promote the well-being of children? These types of question about cause and effect drive decisions across medicine, policy, and business...

I think that is basically the official definition:

Not in syllables though. ME/CFS has five versus four in chronic fatigue, so takes longer to pronounce. Part of the reason I like ME (not that I say it out loud to anyone, just feels less bulky).