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I hope it works out for you! Little else to contribute to the thread as I don't use the pill.

It's good they write it as many are unaware of what the mice are regularly fed, which is problematic when extrapolating to what humans eat. The reason I wanted the normal chow mice data included in the other plots is because we see different prevalences of illnesses between people who move from...

While I think pwChronicIllness need more of certain compounds than others to alleviate the extra stress put on the system by illness, I find it unlikely that patients have a markedly lower isoflavone content in their diet than healthy controls. This quote from the background makes me wonder if...

I would also easily have been excluded from this data. I'm mild/moderate, and have been ill for years, there's very little the GP can do for me. The last years I have mostly gone to see one to get documentation of illness for university, which would be one visit a year. Not everyone has such a...

Zonulin and tight junctions are pretty cool, and possible to influence through environmental factors such as diet and possible sunlight exposure (high vitamin D levels in cell culture is protective against tight junction disruptors, but values used in such studies are higher than what is...

The paper says: The values most closely associated with the date of the documentation of fibromyalgia were used in this study. So it is possible, depending on how often these tests are run where the study was performed. They are using their own facility's cutoff for deficiency, which may be...

Interesting that they've used <400 ng/L as a threshold for deficiency, that is much higher than the lower reference points seen in Norway at least (I've seen the lowest points lie between 140-170 pmol/L, equivalent to 190-230 ng/L). I wonder how the results had been if these lower thresholds had...

I don't think I'd have described it as a head of a causal pathway, but otherwise yes you're on the right track.

Yes. The normal range says little about what the optimal levels for the individual is, and some might be deficient even if they are within the "normal" range. It's so frustrating that even with symptoms of deficiency a lab test within normal (it can even be just within the range!) and everything...

I wish we could be sure things like this were ruled out early as part of a screening, sadly that's not always the case :( Not saying it's the case with you @Daisybell, just a general observation and frustration. :)

Now that you mention it there was an opinion piece from a GP here in Norway recently about how in some litterature relevant for medical professionals diabetes types II is still called "old man's diabetes" while type I is referred to as what occurs in children. This causes problems when people...

I've also seen it the other way around. I don't think I know about any other disease with this type of naming issues..

This is true for the most part, but there are also some mutations that will cause disease.

I've seen this argument so many times I want to scream. Lately I have been thinking how differently we handle bad quality research based on what it is about. Take masks, the argument that they don't work in the real world because people don't use them right is common. With nutrition we continue...

I don't always get it with PEM, but have been the last few times I've overexerted. It's also followed by my skin burning (strongest in the muscles I've used most, but my skin is hot to touch all over). As a kid I would get burning skin so that I could not have my hand on my arm because it hurt...

Coenzyme ;) I'm not a fan of comparing whole classes of compounds between groups (the metabolic cluster figure @Hutan shared) as it might be specific compounds within the groups that are important and differences between whole classes of lipids etc could be due to something so simple as...

I can feel terrible both with and without sound sensitivity, so for me the sound sensitivity is not dependent on already being in a bad state. I also had sound sensitivty as part of my migraines growing up, and then it was usually a warning I was going to get a migraine attack. It is a piercing...

There are some other threads on the forum related to the Bragée ME-center in Stockholm: Two seminars hosted by them: Sweden: Webinar: Gunnar Olsson on ACT for ME, hosted by Bragée ME Center Sweden: Webinar 'Half-time control' Bragee December 2020 A paper on Intracranial Hypertension...

A post on David Oliver withdrawing from the RCP presidency has been moved to the thread: Statement from the RCP and Professor David Oliver, 18 July 2022

Yeah, the potential for harm is huge.