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A new toolkit designed to help enhance research into Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) through funding has been made available for download with the support of the Chief Scientist Office (CSO) After the establishment of a UK Clinical Research Collaboration (UKCRC)...

Abstract Introduction Fatigue is prevalent across a wide range of medical conditions and can be debilitating and distressing. It is likely that fatigue is experienced differently according to the underlying aetiology, but this is poorly understood. Digital health technologies present a...

Abstract The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of the highly contagious respiratory disease Corona Virus Disease 2019 (COVID-19) that may lead to various neurological and psychological disorders that can be acute, lasting days to weeks or months...

Yep. Work being done here in the UK has shown that as well. "White individuals were approximately 5-fold more likely to be diagnosed with ME/CFS than others; black, Asian or Chinese ethnicities are associated with particularly low rates of ME/CFS diagnoses. This ethnicity bias is stronger than...

With the next General Election taking place on Thurs 4th July, the updated information from the Electoral Commission is that "The deadline to apply for a postal vote in the Parliamentary general election is 5pm on Wednesday 19 June. You must also be registered to vote by 11:59pm on Tuesday 18...

Abstract Introduction Illness perception refers to patients’ subjective representations and appraisals of somatic and mental symptoms. These are relevant for self-management and outcome. In clinical practice, patients with functional neurological disorder (FND) often encounter a fragmented...

"The FND of movement and sensation has a prevalence of roughly 50 per 100 000 population and an incidence of 4–12 per 100 000 population per year. FS contributes a further 1.5–4.9 per 100 000 population per year, with a prevalence of 2–33 per 100 000 population.5 Patients with FND make up 9% of...

Abstract Introduction Functional neurological disorder (FND) is a common cause of referral to neurology services. FND has been shown to lead to significant healthcare resource use and is associated with significant disability, comorbidity and distress. This leads to substantial direct...

Encephalitis is inflammation of the brain Encephalomyelitis is inflammation of the brain and spinal cord. Myalgic is muscle pain. Of the eight references that the author quotes, five use "myalgic encephalomyelitis" and the other three do not expand on ME. None use "myalgic encephalitis". Am...

What's that then? The same as myalgic encephalomyelitis/chronic fatigue syndrome?

"All participants were evaluated for the presence of criteria related to ME/CFS based on the DSQ; namely: fatigue (I), post-exertional malaise (II), sleep difficulties (III), pain (IV), neurological/cognitive manifestations (V), and other (VI) which included autonomic, neuroendocrine, and immune...

Not sure I agree from the description they give. "The second cohort consisted of 34 LC patients with ME/CFS (median age 48 ± 9.8, 25 females and 9 males) and 34 patients recovered (median age 45 ± 11.39, 24 females and 10 males) from SARS-CoV-2 infection without any long-term symptoms per se...

Published papers thread for w/c 20th May Facebook: https://www.facebook.com/sci4me/posts/pfbid0E2fKkBL8XYRDZTEs7xZMQPi88ny4VPp6bv51DRqdLthk2FGCz8hsbPuaMsoXizkgl Mastodon: https://med-mastodon.com/@s4me/112511986896956087

$49,120 raised, 75% of total. 5 days left. https://crowdfund.berkeley.edu/project/42302

Highlights ALS-linked A4V SOD1 mutant is not able to regulate aerobic glycolysis as WT SOD1. PDH activity and E1α phosphorylation are impaired in A4V human SOD1 cells. A4V mutation reduces SOD1 activity and impacts glucose consumption rate. Abstract Under certain stress conditions...

Abstract Background: Recent evidence has identified great promise for the novel whole-body photobiomodulation therapy (PBMT) for individuals with fibromyalgia (FM). However, currently no evidence has documented the experiences of participants. The objective of this study was to qualitatively...

Full title: The Association of Central Sensitisation with Depression, Anxiety, and Somatic Symptoms: A Cross-Sectional Study of a Mental Health Outpatient Clinic in Japan Abstract For patients with chronic pain and persistent physical symptoms, understanding the mechanism of central...

Abstract Functional somatic disorders (FSDs) are common in children and adolescents. Recent findings suggest that low-grade inflammation has a role in the development and maintenance of pediatric FSDs. This systematic review included studies with original data on systemic inflammatory markers...

Highlights Joint Hypermobility was found in almost three quarters of people with FND surveyed. Joint Hypermobility was a stronger predictor of FND than depression or anxiety. Joint Hypermobility moderated the contribution of anxiety to the risk of FND. Abstract Background Functional...

Abstract Background: Patients who were infected with COVID-19 may experience Long COVID syndrome. We examined the effectiveness of physiotherapy on dyspnea, muscle strength, and functional status in Long COVID syndrome. Methods: The exercise group underwent an 8-week supervised...