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As per the thread title, this thread will be a compilation of currently active research funded by UK sources. Previous threads: What ME/CFS research, funded by UK sources, is currently in process (as of end June 2019)? What ME/CFS research, funded by UK sources, is currently in process (as of...

Abstract: Background Myalgic encephalomyelitis / chronic fatigue syndrome (ME/CFS) is a chronic neurological disease, with fluctuating symptoms affecting multiple body systems, including nervous and immune systems. ME/CFS affects around 250,000 people in the UK and 17 million people worldwide...

Abstract Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a condition characterised by extreme fatigue, memory impairment, pain and other symptoms that vary from patient to patient. It affects about 0.9% of the population and is often triggered by an acute viral or bacterial...

Abstract This project explores the "recovery narrative" within anglophone writing through a creative piece of nonfiction, as well as a critical reading of contemporary "illness memoirs". Representations of recovery in literature largely follow a particular, teleological, narrative arc. My...

Highlights Studies were identified across the last century involving 1584 participants. >85% of patients demonstrated clinically significant improvements. >75% had a resolution or near resolution of symptoms in the short-term. The evidence base shared limitations with that for other...

"We are happy to announce the recipients of the 2023 Johadamis ME/CFS € 100.000 Research Grant for the project "UNRAVELING ME/CFS": The Role of Hidden Viral Infections in Peripheral Blood and Gut-Specific Lymphatic Tissue in the Pathogenesis of ME/CFS (Myalgic Encephalomyelitis/Chronic Fatigue...

Full title: Identification of CD8 T-cell dysfunction associated with symptoms in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and Long COVID and treatment with a nebulized antioxidant/anti-pathogen agent in a retrospective case series Highlights Both Long COVID and ME/CFS are...

[In mice] Mitochondria adapt to increased energy demands during muscle contraction by acutely altering metabolite fluxes and substrate oxidation. With age, an impaired mitochondrial metabolic response may contribute to reduced exercise tolerance and decreased skeletal muscle mass, specific...

9,821 signatures at time of posting. https://www.change.org/p/cochrane-withdraw-the-harmful-2019-exercise-therapy-for-cfs-review

Now published, open access, https://onlinelibrary.wiley.com/doi/10.1111/pai.14060

It's a poster presentation, the PDF of the poster can be seen here, https://www.ispor.org/docs/default-source/euro2023/isporeurope23cochraneee238poster129030-pdf.pdf?sfvrsn=7e519db0_0 Also attached

Background: Around 10% of people who had COVID-9 infection suffer from persistent symptoms such as fatigue, dyspnoea, chest pain, arthralgia/myalgia, sleep disturbances, cognitive dysfunction and impairment of mental health. Different underlying pathomechanisms appear to be involved, in...

Published papers thread for w/c 18th Dec. Facebook: https://www.facebook.com/sci4me/posts/pfbid0ThSX1idphVHc5G6TENKViCsT61fdikqEdJxRhXRUHcVATUSG54btgAJyXn3G7ARZl Mastodon: https://med-mastodon.com/@s4me/111645927909375787

Yep.

The following tweet denies this "Hi Stephen, I still run my own social media despite being privileged to work with Dr Proal. What I meant in this comment the Christoph is that in folks with LC (and now in vaccine injury as we have been studying pw vaccine injury with Dr Iwasaki) is we see immune...

Three unemployed people explain how they feel targeted by the Tories over their inability to join the workforce ... Others have been forced out of work after an injury. Jordan, 27, was in the early months of a history PhD in Leicester in January 2022 when she suffered a minor head injury after...

Full title: Responsiveness and meaningful thresholds of PROMIS pain interference, fatigue, and physical function forms in adults with idiopathic inflammatory myopathies: Report from the OMERACT Myositis Working Group Background A series of qualitative studies conducted by the OMERACT Myositis...

ABSTRACT Cancer-related fatigue (CRF) is a distressing side effect of cancer and treatment, affecting both patients during active treatment and survivors, negatively impacting quality of life. While its exact cause remains uncertain, various mechanisms such as immune dysfunction, HPA-axis...

We have had decades of patients using their own words to describe their symptoms, using such words as tired or fatigued. Definitions from various online dictionaries, Tired - " in need of rest or sleep", "weary; fatigued", "depleted of strength or energy", "feeling that you want to rest or...

The incredible story of the PACE trial for ME/CFS | Part 1 How a phase 3 clinical trial went off the rails and led patients around the world to receive inappropriate therapies which, in some cases, caused them profound and lasting harm...