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  1. J

    The Playbook Used to ‘Prove’ Vaccines Cause Autism

    “Every dollar spent relitigating the disproven vaccine-autism link is a dollar stolen from research that could actually help people with autism — studies on support services, educational interventions, employment programs and other factors behind autism. This is the cruelest irony: that those...
  2. J

    The Playbook Used to ‘Prove’ Vaccines Cause Autism

    This is a well done article with helpful graphics. Basically shows how two not-good people were able to manipulate studies to get their desired results. https://www.nytimes.com/interactive/2025/08/19/opinion/vaccines-autism-evidence.html?unlocked_article_code=1.fU8.yt_3.Wwm6mMNDUmCI&smid=url-share
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    Serum BAFF and APRIL Levels, T-Lymphocyte Subsets, and Immunoglobulins after B-Cell Depletion Using Rituximab in MECFS 2016 Lunde Fluge

    Bumping this thread again. Does anyone know why there hasn’t been much/any follow up on this BAFF finding? Maybe I missed some studies? Baseline differences don’t look dramatic but they were significant. Thanks. @SNT Gatchaman @ME/CFS Science Blog @Hutan
  4. J

    A Study to Assess Anktiva in Patients With Long Covid-19. (INTERRUPT_LC)

    Why are they giving by intravesical for LC?
  5. J

    A Study to Assess Anktiva in Patients With Long Covid-19. (INTERRUPT_LC)

    The wholesale acquisition cost (WAC) for one dose of Anktiva is $35,800.
  6. J

    A Study to Assess Anktiva in Patients With Long Covid-19. (INTERRUPT_LC)

    Anktiva boosts NK cells. How ANKTIVA Works: IL-15 Agonist: ANKTIVA is a fusion protein that mimics the action of interleukin-15 (IL-15), a cytokine that stimulates immune cells. Activates NK Cells: It enhances the activity and proliferation of NK cells, which are part of the innate immune...
  7. J

    The bone marrow immune ecosystem shapes daratumumab acquired resistance in plasma cell myeloma 2025 Wang et al.

    Abstract Daratumumab, an anti-CD38 monoclonal antibody, is an effective therapy for plasma cell myeloma (PCM). However, many initial responders relapse. We compared paired samples from subjects pre-therapy and then acquired resistance to daratumumab. We first used single-cell RNA sequencing and...
  8. J

    Serum BAFF and APRIL Levels, T-Lymphocyte Subsets, and Immunoglobulins after B-Cell Depletion Using Rituximab in MECFS 2016 Lunde Fluge

    If BAFF is high why not give belimumab along with Daratumumab? https://en.wikipedia.org/wiki/Belimumab
  9. J

    Serum BAFF and APRIL Levels, T-Lymphocyte Subsets, and Immunoglobulins after B-Cell Depletion Using Rituximab in MECFS 2016 Lunde Fluge

    Lunde S, Kristoffersen EK, Sapkota D, Risa K, Dahl O, Bruland O, et al. (2016) Serum BAFF and APRIL Levels, T-Lymphocyte Subsets, and Immunoglobulins after B-Cell Depletion Using the Monoclonal Anti-CD20 Antibody Rituximab in Myalgic Encephalopathy/Chronic Fatigue Syndrome. PLoS ONE 11(8)...
  10. J

    Dr Michael Scoma

    Brandi Glanville has 800,000 followers on Twitter/X That’s a lot. UK people on here probably thinking that they never heard of her because she is an American celebrity. FWIW I’m American and never heard of her till yesterday. These Housewives “stars” tend to become most famous when they do...
  11. J

    Dr Michael Scoma

    Seems like Scoma fixed her facial parasites or something. https://www.tmz.com/2025/08/15/brandi-glanville-new-face/
  12. J

    Dr Michael Scoma

    Umm not sure what to say here…… Really don’t know what to say.
  13. J

    Metrodora Clinic news and discussion (Salt Lake City area)

    That’s strange…a lot of wealthy folks backed it.
  14. J

    USA: Mount Sinai PACS clinic and Dr David Putrino

    More Putrino controversies about exercise/GET. Thread. This is an issue that has been coming up today from various folks and I want to address it. As I said when we launched the manual, this is the beginning of a conversation, not the "final word". I also want to say that reading it with...
  15. J

    Human Long-Lived Plasma Cells Acquire Resistance to Proteasome Inhibitor-Based Desensitization Treatment by Upregulating Autophagy 2025 Burg et al.

    Purpose: The use of proteasome inhibitors, such as bortezomib (BTZ), to target anti-HLA antibody (aHLA Ab)-producing plasma cells (PCs) is a promising emerging therapeutic to combat antibody-mediated rejection (AMR) and to reduce HLA sensitization via desensitization regimens. However, as with...
  16. J

    A Study to Assess Anktiva in Patients With Long Covid-19. (INTERRUPT_LC)

    Here is PS-S—-likely the world’s wealthiest physician. He and his daughter are sort of controversial figures in the USA. https://en.wikipedia.org/wiki/Patrick_Soon-Shiong
  17. J

    Clinical Update | Ultra-Low-Dose Metabolically Armed CD19 CAR-T Successfully Treats First Systemic Lupus Erythematosus Patient

    https://www.lemanbio.com/en/news/339.html The first enrolled systemic lupus erythematosus (SLE) patient achieved "medication-free DORIS remission" (complete remission without ongoing treatment) after receiving a single infusion of Meta10-19 injection at a dose of only 1‰ (one-thousandth) of the...
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