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The recent UngData found that 20% of adolescents experienced abuse "for the first time" during the first months/year of the pandemic. That also got into a lot of headlines despite being similar to previous years and likely not a "pandemic effect". Also "abuse" in this context include things like...

An opinion piece on how to diagnose functional disorders in children and young people, using a biopsychosical model of understanding symptoms. I thought it was nice for understanding how biopsychosocial is used by some healthcare workers. Basically it advertises to look for a limited set of...

To quote a professor I worked with briefly: "NFkB is seen in everything". Also Wnt. He worked with inflammatory bowel disease and autoimmunity. Off topic but I really enjoy we have a protein called "Frizzled" here :laugh: Back on topic: I I do enjoy it when oxidative stress and problems with...

Moved post Not an article or anything, but reading about long covid kids and sudden hospitalizations reminded me of being hospitalized with presumed organ failure following a PEM crash at my GP. The elevator was non-functioning, I had to take the stairs and I crashed during the examination...

Norwegian article, a personal trainer that got a mild case of covid, and discovered that a month later she did not perform well in her workout sessions and this has continued. While I didn't like the article as I feel it has a positive spin for no reason, it's nice to have another story that...

The female metabolome might also be influenced by the menstrual cycle, just to make it even more complicated.

Different splice variants are found in single humans, and splice variants can also vary by tissue type.

Reduced food intake can be protective in that the body then requires less energy for digestion and dealing with potential post-prandial inflammation (possibly higher in pwME, especially after exertion given the increase seen in LPS in the blood), but at the same time it is very easy to become...

Autophagy and calorie restriction is seen in some, not all, animal studies. There's a lot of hype surrounding fasting, sprinkled with the old morality of how much better of a person you are if you can restrict yourself from eating. Comparing studies on fasting is a nightmare, as protocols...

It's not just Berquist that does this, Fluge/Mella/Tronstad still talks about autoimmunity as a potential cause of ME/CFS, I think they went through their reasoning in a paper discussed on here a while ago (sorry don't remember the title).

Yes :( Not so long ago a woman was in the news telling her story of becoming incontinent after giving birth and how she was fobbed of with that she should train her muscles etc., while the real problem was a damage she sustained while giving birth. A small operation and she was no longer...

You "just" follow a schedule for when to urinate and gradually decrease the number of times a day. Didn't work very well for me as the problem would return with PEM, and suddenly it wasn't an issue anymore although it was a consistent PEM signal for me for a year or so, and at that time I also...

Are you perhaps thinking of calcium not vitamin D? Vitamin D levels would not be described as "farly constant", although with calcium it takes a lot for them to get out of range. I've heard magensium can be sequestered from bone like calcium is to maintain serum levels, but I've tried looking...

As I said, repeating what I've been taught. The evidence behind it is not presented alongside the lectures ;) It's the same in Norway as the NIH fact sheet states, overt deficiency is rare, but inadequacy is common for a number of reasons. In some groups more so than others.

My n=1 is that urine is normal on normal tests including salts (was lucky to have this tested when I had polyuria for extended time), but it was the muscles of my blader that was the problem. Unfortunately the treatment offered was retraining my bladder, which in no way took it into account...

We've been taught that transdermal magnesium is an alternative to oral, but I don't know what evidence is behind this. As we know health care can also but into hype ;) One thing that transdermal magnesium is said to be good at is delivering magnesium at the spot where it's needed, ie if you...

A very important point.

A journal club, as I know it, is people getting together discussing a research paper. We had one in the neurobiology-group I spent some time with.

A mostly nice article about long covid in NRK today, with Sidsel Fjelltun (psychologist wirking with chronic pain patients), Jonas Kunst (prof. in psychology) and Ola Saugstad (GP, and works with the Norwegian ME Association) on the "you can't think yourself well", and Henrik Vogt and a mention...

Folate is found in foods that a lot of people don't eat enough of, such has fruit/vegetables/whole grains/legumes. In observational studies males typically eat less of these foods than females, and it's easy to not get enough through diet alone. At the same time a folate deficiency can be masked...