Full title: Chronic inflammation, neuroglia dysfunction, and plasmalogen deficiency as a new pathobiological hypothesis addressing the overlap between post-COVID-19 symptoms and myalgic encephalomyelitis/chronic fatigue syndrome
Highlights
Plasmalogens (Pls) are lipids containing a...
Published papers thread for w/c 3rd July
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Frustrating that when the article is talking about UK ME/CFS research that DecodeME isn't mentioned (although I may be slightly biased there) and surprising that they don't talk about Invest in ME's efforts that are looking at the gut microbiome.
Not sure why they aren't referencing the newer guideline,
"NICE published guidelines in 2007 to help quantify fatigue severity in the context of ME/CFS."
Key points
According to recent data from the US Census Bureau and CDCs National Center for Health Statistics, 7.5% or one in 13 patients diagnosed with coronavirus disease 2019 (COVID-19) reported long-term symptoms.
Because of the varied possible etiologies causing post-acute sequelae of...
News in Brief posts for w/c 3rd July
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John Pring from Disability News Service is asking on Twitter,
"Many of you will know of the notorious 'Malingering and illness deception’ conference held in Woodstock, near Oxford, in November 2001, which was funded by DWP. Does anyone know the name of the hotel where the conference took place?"
Abstract
Background: Functional neurological disorders (FND) lead to increased care requirements and costs, negatively impacting healthcare budgets. Healthcare expenditure in FND has escalated beyond other neurologic disorders during the past decade.
Objectives: To assess inpatient costs in...
Martine McCutcheon still affected by illness.
"In her caption, Martine spoke candidly about her struggles with chronic fatigue syndrome and fibromyalgia – a condition which causes widespread pain and extreme tiredness."
"She penned: "What A GREAT Gatsby Night to remember! I haven't been out...
Introduction
The importance to assess and include the frequent comorbidities in the personalised care management plan of patients with functional neurological disorders (FND) has arisen through the years. FND patients are not only complaining from motor and/or sensory symptoms. They also report...
Background
Until the outbreak reported during the COVID-19 pandemic, functional tics were considered to be a relatively rare clinical phenotype, as opposed to other functional movement disorders such as functional tremor and dystonia. In order to better characterise this phenotype, we compared...
Abstract
Background
Up to 10% of children and young people have a specific phobia that can significantly affect their mental health, development and daily functioning. Cognitive–behavioural therapy-based interventions remain the dominant treatment, but limitations to their provision warrant...
Full title: Long-term clinical and cost-effectiveness of a therapist-supported online remote behavioural intervention for tics in children and adolescents: extended 12- and 18-month follow-up of a single-blind randomised controlled trial
Background
Little is known about the long-term...
Background
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a multifactorial illness that affects many body systems including the immune, nervous, endocrine, cardiovascular, and urinary systems. There is currently no universal diagnostic marker or targeted treatment for ME/CFS...
"There are plenty of reasons to get off your duff and exercise—but is improving your brain one of them? The U.S. Centers for Disease Control and Prevention touts exercise as a way to “boost brain health,” while the World Health Organization suggests that about 2 hours of moderate activity or 75...
Why Some People Get Sick More Often
"Everyone gets sick. Despite all the vegetables we eat or vitamins we gulp down, sooner or later pathogens such as viruses and harmful bacteria infiltrate our bodies, and we need to take a time-out. We sit back and let our immune system do its job.
But when...
Abstract
Some people remain healthier throughout life than others but the underlying reasons are poorly understood. Here we hypothesize this advantage is attributable in part to optimal immune resilience (IR), defined as the capacity to preserve and/or rapidly restore immune functions that...
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