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"Given the substantial societal impact of chronic stress and fatigue, there is a need for further investigation into symptom presentation, diagnostic characterization, and steps towards standards regarding outcome domains to measure in clinical trials. Indeed, a recent review of all published...

"In response to increasing sick leave rates due to mental disorders in the late 1990's in Sweden, together with clinical observations that many sick-listed individuals reported prolonged exposure to psychosocial stressors and symptoms of fatigue, tentative criteria for a new diagnosis...

Diagnostic Criteria for exhaustion disorder (ED) (F43.8 A) A. Physical and mental symptoms of exhaustion during at least 2 weeks. The symptoms have developed in response to one or more identifiable stressors, which have been present for at least 6 months. B. Markedly reduced mental energy...

Apologies if I'm duplicating anything but I wonder if what they did in this study might have some relation to Dr Alan Moreau's new, low-stress protocol for provoking PEM.[Thoughts?], which also involves an arm pressure cuff. The thought was inspired by spotting this, Preprint: Altered Tissue...

For published version see Altered tissue oxygenation in patients with post COVID-19 syndrome (2023, Microvascular Research) ******************** Pre-Print https://www.researchgate.net/publication/369239099_Altered_Tissue_Oxygenation_in_Patients_with_Post_COVID-19_Syndrome Background: Post...

Objective Sleep disturbance may constitute health problems for the afflicted individual, but documentation of its chronicity is sparse. The objective was to investigate the extent to which incident and chronic sleep disturbance are associated with stress, mental ill-health and functional somatic...

Abstract Objectives Post-acute sequalae of SARS-CoV-2 infection (PASC) is not well defined in pediatrics given its heterogeneity of presentation and severity in this population. The aim of this study is to use novel methods that rely on data mining approaches rather than clinical experience to...

Background Intravenous immune globulin (IVIg) is frequently used in some neurological diseases and is also the first-line therapy in Guillain-Barré syndrome, chronic inflammatory demyelinating polyneuropathy, and multifocal motor neuropathy. We aimed to evaluate the frequency and characteristics...

"Among the 3406 participants, 175 were excluded due to having responded to less than half of the items on the SMBQ, PHQ-15 and/or HADS, resulting in a study sample of 3231 participants. Of these, 687 met the criterion for burnout (global SMBQ score ≥ 3.75), and the remaining 2544 participants...

Highlights • Fatigue, pain and gastrointestinal symptoms are particularly common in burnout. • These symptoms show 2- to 9-fold increased risk when adjusted for negative affect • The risk of burnout increases 1.52 times with each additional symptom Abstract Objective Burnout results in...

In case anybody has the stomach to watch it. "In this Dystonia Facts video Prof Mark Edwards, St George’s University Hospital, London UK covers Functional Dystonia also known as Psychogenic Dystonia.The importance of properly diagnosing the condition and treatment plans that follow."

I have just received this reply from the email that I sent to pressoffice@cochrane.org "Dear Andy, Thank you for getting in touch. The update is currently underway and we are hoping to publish the protocol for consultation in the coming months. Unfortunately I am not in a position to be more...

Abstract Intensive Short-Term Psychodynamic Therapy (ISTDP) has demonstrated promising evidence for the treatment of Functional Neurological Disorders (FND) including functional seizures. This paper aimed to further examine the therapeutic effects of a 3-session course of this treatment...

Abstract Background COVID-19 is associated with a dysregulated immune response but it is unclear how immune dysfunction contributes to the chronic morbidity persisting in many COVID-19 patients during convalescence (long COVID). Methods We assessed phenotypical and functional changes of...

Full title: Physical health of Post-9/11 U.S. Military veterans in the context of Healthy People 2020 targeted topic areas: Results from the Comparative Health Assessment Interview Research Study Abstract Large-scale epidemiological studies suggest that veterans may have poorer physical health...

Thread for UK: Action for ME: Media Guidelines for reporting on M.E.

"We’re delighted to launch our media guidelines to better inform media stories on Myalgic Encephalomyelitis (M.E.) For too long, people with Myalgic Encephalomyelitis (M.E.) have struggled to get their condition diagnosed, understood, and acknowledged. .... We want to work with journalists to...