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"In diagnosing CFS, the Institute of Medicine (IOM) criteria were applied"

Interesting. I searched for studies looking for cell-free DNA in ME/CFS patients and found one that found no difference with controls, Analysis of 16S rRNA gene sequences and circulating cell-free DNA from plasma of chronic fatigue syndrome and non-fatigued subjects 2002 Vernon et al, and one...

"The patients attended a private practice specializing in ME/CFS and all satisfied the Centers for Disease Control (CDC) diagnostic criteria for CFS [5]. A review of the clinical notes shows that most, if not all, patients also satisfied the more stringent ICCME"

Abstract The objectives of this study are to test the hypothesis that the fatigue and accompanying symptoms of Chronic Myalgic Encephalomyelitis/Fatigue Syndrome are in part due to defects in energy provision at the cellular level, and to understand the pathophysiology of the defects so that...

Fukuda selection criteria.

Background The association of an infectious agent with chronic fatigue syndrome (CFS) has been difficult and is further complicated by the lack of a known lesion or diseased tissue. Cell-free plasma DNA could serve as a sentinel of infection and disease occurring throughout the body. This type...

"Out of 18 pSS patients that completed evaluation for the CCC (Figure A1 of the Appendix A), 13 patients fulfilled criterion 1, stating that they were experiencing significant fatigue. Eleven of those patients stated that they were experiencing PEM after mental or emotional exertion, with only...

Another one for @dave30th :)

Background In 2021 the European Academy of Neurology's training requirements were updated to include Functional Neurological Disorder (FND) as a core topic for the first time. To reinforce these changes, we aimed to understand the proportion of inpatients (in non-neurology settings) who are...

Objectives Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a chronic systemic disease that leads to neurological, immunological, autonomic, and energy metabolism dysfunction. COVID-19 has been reported to cause similar symptoms to ME/CFS. The study aims to investigate the...

"ME/CFS is diagnosed according to clinical criteria and after exclusion of other diseases that might explain the symptoms [48]. In adults the systemic exertion intolerance disease (SEID)/Institute of Medicine (IOM) criteria [49] are recommended for screening and the Canadian Consensus Criteria...

Merged thread The rate of Americans developing a rare meat allergy from tick bites is rising, researchers say, and may have already impacted as many as 450,000 people. New data released by the Centers for Disease Control and Prevention (CDC) on Thursday shows a steep increase in cases of...

Don't think this deserves a thread of its own, but thought it should be noted in case @dave30th wants to check the claims made Functional neurological disorder: a review, 2023, Dusara et al, published in British Dental Journal Abstract Functional neurological disorder is a common condition...

Or an alternative take is to praise how well he has listened to patients and, in taking them seriously, accurately reflected what they said in his writing while still making the article readable. There is far more to the article than a simple regurgitation of patients' accounts. Additionally...

Text from Ed Yong tweets, "When long-haulers talk about their fatigue, they often hear “Oh I’m tired too”. But theirs is utterly different to the everyday version healthy people get. More severe. Very hard to push through (& costly if you try). Not cured by sleep. Multifaceted."...

For those unable to view the tweet, Ed says "First, an important note. I’ve been told that this piece will be free to read for 24 hours, but will then go behind the paywall. Best I could do. If you’re not a subscriber and this is useful to you or your loved ones, I’d suggest saving a copy ASAP."

"COVID-19 may no longer be considered a public health emergency, but post–COVID-19 condition—also known as long COVID—remains a hurdle, according to the US Department of Health and Human Services (HHS). Through the Substance Abuse and Mental Health Services Administration (SAMHSA), HHS issued a...

Objectives: Fatigue is a common symptom in children with inflammatory bowel disease (IBD). Diagnostic tests to evaluate biological causes of fatigue commonly include markers of inflammation and haemoglobin (Hb), yet functional parameters have been inadequately studied in paediatric IBD. In...

"Some patients with Ehlers–Danlos syndrome-hypermobility type/joint hypermobility syndrome (EDS-HT/JHS) may suffer from Craniocervical Instability (CCI). CCI can result in continuous microtraumas and inflammation on craniocervical joint surfaces. It causes repetitive peripheral sensitization...

Full title: Perioperative opioid-minimization approach as a useful protocol in the management of patients with Ehlers–Danlos syndrome-hypermobility type, craniocervical instability and severe chronic pain who are to undergo occipito-cervical fixation Patients suffering from connective tissue...