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Abstract Retrograde menstruation is a widely accepted cause of endometriosis. However, not all women who experience retrograde menstruation develop endometriosis, and the mechanisms underlying these observations are not yet understood. Here, we demonstrated a pathogenic role of Fusobacterium...

Background Hydrogen gas (H2) is a common product of carbohydrate fermentation in the human gut microbiome and its accumulation can modulate fermentation. Concentrations of colonic H2 vary between individuals, raising the possibility that H2 concentration may be an important factor...

Completely expected bog standard response which this petition was always going to receive.

Background Although functional neurological movement disorders (FMD) are characterized by motor symptoms, sensory processing has also been shown to be disturbed. However, how the integration of perception and motor processes, essential for the control of goal-directed behavior, is altered in...

Abstract Lactate shuttled from the blood circulation, astrocytes, oligodendrocytes or even activated microglia (resident macrophages) to neurons has been hypothesized to represent a major source of pyruvate compared to what is normally produced endogenously by neuronal glucose metabolism...

Abstract Previous studies on the natural history of long-COVID have been few and selective. Without comparison groups, disease progression cannot be differentiated from symptoms originating from other causes. The Long-COVID in Scotland Study (Long-CISS) is a Scotland-wide, general population...

No, open access at the link you give, https://www.nature.com/articles/s41598-023-35991-y

Now published. Abstract As six patient partners in Canada, we aim to contribute to learning and to provide an opportunity to reflect on patient engagement (PE) in research and healthcare environments. Patient engagement refers to “meaningful and active collaboration in governance, priority...

Background Previous studies have found that adolescents with a chronically ill parent may experience more internalizing problems. It is less clear if this association is sex-related, and whether it is specific for functional somatic symptoms (FSSs) or concerns other internalizing or...

Background The condition known as chronic fatigue syndrome or myalgic encephalomyelitis (CFS/ME) is poorly understood. Simplified medical models tend to neglect the complexity of illness, contributing to a terrain of uncertainty, dilemmas and predicaments. However, despite pessimistic pictures...

Fine ideas, the standard challenge though will be finding volunteers who have the capacity to work on it. I don't, mainly due to my involvement in DecodeME (if you haven't yet take part here), hopefully there might be some who can take these ideas forward.

Published papers thread for w/c 5th June. Facebook: https://www.facebook.com/sci4me/posts/pfbid0K2XVTAfVzZXvgD3tDVjFqcTCf7Lcmve595JvTMREPeY6kz9rTKf6dDEepeTTbgNVl Mastodon: https://med-mastodon.com/@s4me/110530112425824707

Situations Vacant: Fundraising Manager Deadline for applications: Friday 16 June 2023 at 5pm. https://meassociation.org.uk/2023/06/situations-vacant-fundraising-manager/

Abstract Depression is often framed as a disease or dysfunctional syndrome, yet this framing has unintended negative consequences including increased stigma. Here, we consider an alternative messaging framework – that depression serves an adaptive function. We describe the historical...

I said So I don't agree, obviously they are open to individuals and specific organisations, but their positioning in general is to be, and be seen to be, as outsiders, which I don't think is as useful overall as it used to be.

News in Brief posts for w/c 5th June Facebook: https://www.facebook.com/sci4me/posts/pfbid0EKq19sTA21GyF4foBW26Yxxpghhq8sSBcWLa6uGhjnhHBWU4VozZxKH8J1PBEFBcl Mastodon: https://med-mastodon.com/@s4me/110525278639243249

For all the time I've been aware of them IiME have seemed to deliberately set themselves apart from not only the other ME/CFS organisations in the UK but also the whole research system in general. While I can understand why they may have done that in that past, I think that enough has changed to...

Webinar: Long Covid: What Needs To Happen Next, 5th and 6th July Click thumbnail for more detail or see tweet below.

Response to this paper from Kachaner et al, https://onlinelibrary.wiley.com/doi/10.1111/ene.15911 Paywalled, so I'm unable to provide an abstract/preview.

"Introduction In the 1960s, Aaron Beck developed cognitive behavior therapy (CBT) or cognitive therapy. Since then, it has been extensively researched and found to be effective in a large number of outcome studies for some psychiatric disorders, including depression, anxiety disorders, eating...