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  1. Snow Leopard

    Increased risk of chronic fatigue syndrome in patients with inflammatory bowel disease: a population-based retrospective cohort study (2019) Tsai et a

    The study isn't bad, but there is a potential red flag, namely these authors are fishing in the data retrospectively for associations... Now if the authors preregistered their hypotheses and mentioned which hypotheses were tested and found to have null results, their results could be interpreted...
  2. Snow Leopard

    Golden hour (/month)

    I can't say I've ever experienced a "golden hour" or anything short term resembling remission...
  3. Snow Leopard

    Who said: don't bother testing patients?

    Makes you wonder why the actual authors didn't bother to read it to make sure there were no errors in the publication.
  4. Snow Leopard

    Intimidation of PACE critics or critics of other Psychosocial research

    Simon Wessely's "biomedical" research was really designed and conducted by colleagues/grad students, such as Anthony Cleare who did do some novel neuroendocrinology work, but unfortunately didn't find anything particularly interesting.
  5. Snow Leopard

    Who said: don't bother testing patients?

    I have discussed the directionality of symptoms before, namely cognitive effort leads to cognitive PEM, whereas a sufficient amount of physical exercise leads to both physical "crash" and cognitive "crash". The sensory issues only come when everything is really severe - only when the brain is...
  6. Snow Leopard

    Esther Crawley

    See: https://forums.phoenixrising.me/threads/recording-of-esther-crawley-inaugural-lecture-on-february-24.49493/
  7. Snow Leopard

    Concerns about Cochrane

    ¯\_(ツ)_/¯
  8. Snow Leopard

    Central sensitization: a matter of concern

    More GIGO. The problem is the lack of prospective studies. What you get is selection bias - eg only people who believe in the association actually submit their questionnaires to the researchers.
  9. Snow Leopard

    Long Term Follow up of Young People With Chronic Fatigue Syndrome Attending a Pediatric Outpatient Service, 2019, Rowe

    I agree. It is hard to have an "absolute measure" of recovery though, as there is no true basis for a clear demarcation
  10. Snow Leopard

    Long Term Follow up of Young People With Chronic Fatigue Syndrome Attending a Pediatric Outpatient Service, 2019, Rowe

    The concept of "recovery" is always sketchy when you have been ill for so long and no real point of comparison to know what that is.
  11. Snow Leopard

    Analysis: “Nothing about us without us”—patient partnership in medical conferences, 2016, Chu et al

    Agreed. It's too easy to be seen to be doing the right things with regard to "involvement", while you're actually stacking the deck against any substantial changes being made.
  12. Snow Leopard

    Illness perceptions in adolescents with CFS (2019) Cara Haines, Maria Loades, Cara Davis

    That is Esther Crawley's clinic. http://www.ruh.nhs.uk/patients/services/clinical_depts/paediatric_cfs_me/info.asp This shows clear selection biases in the CFS patients that does not necessarily exist in the other samples, namely referal to a clinic that focuses on psychological treatments...
  13. Snow Leopard

    Star Advertiser: Is chronic fatigue syndrome real? [Dr Oz claiming that there is a test for ME/CFS]

    I'd say no it is not. It is hard to say, but population based studies have found similar (often higher, but that could be due to methodological difference) prevalence in South American and Asian populations, as well as in non-white populations in the USA and UK.
  14. Snow Leopard

    USA: Center for Solutions for ME/CFS - news and updates from Columbia University's NIH funded center, Lipkin

    Okay, thanks for letting us know. It seems quite unprofessional that there was no communication throughout the process, including no announcement that a committee has been selected.
  15. Snow Leopard

    My Label and Me: I’m not tired and lazy, I have ME

    The sad part is he's not going to recover using their programme...
  16. Snow Leopard

    Myalgic encephalomyelitis or chronic fatigue syndrome: how could the illness develop?(2019) - G.Morris,Maes,Berk,Puri

    It's an interesting hypothesis, but unfortunately, it's also almost certainly wrong.
  17. Snow Leopard

    The invisible burden of chronic fatigue in the community - a narrative review (2019), Fatt et al

    I don't understand why they're talking about "conversion" of chronic fatigue into CFS. The demarcation is purely diagnostic - whether there is another medical condition that is presumed to cause the symptoms or the symptoms have lasted more than 6 months, to meet the CFS criteria. The...
  18. Snow Leopard

    Exercise Intolerance in Preload Failure Treated with Pyridostigmine (2018) Faria Urbina et al (mentions ME/CFS & POTS)

    The results provided in the abstract aren't the ones of interests - it is not peak cardiac output or VO2Peak that we are interested in, because it's possible that patients simply worked harder on the second test and achieved a higher heart rate. We're interested in stroke volume and O2 pulse...
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