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  1. Alvin

    CDC gets list of forbidden words

    The government of Canada was muzzling scientists so this is not at all unprecedented :emoji_face_palm: It didn't end well but much damage was done I highly doubt that the point is to fight clichés, coming from leaders that are disdainful of science and reality.
  2. Alvin

    Esther Crawley talk at TEDxBristol, Thurs 2nd Bristol - "Disrupting Your View Of ME"

    I see :( Does anyone have any contacts at a major newspaper, say someone willing to write an article that Ted is protecting quacks?
  3. Alvin

    Esther Crawley talk at TEDxBristol, Thurs 2nd Bristol - "Disrupting Your View Of ME"

    Can two play this game, can we create an opposing video and put it on TEDx? Any volunteers?
  4. Alvin

    CDC gets list of forbidden words

    Never if his apologists in the senate can prevent it, they are now reportedly trying to dismiss Mueller's investigation into Trump's treason with Russia. Its amazing that the right cries censorship nonstop when they are the ones practicing it. People voted for alternative facts and they are...
  5. Alvin

    Tuller / Trial By Error: The Crawley Chronicles, Resumed

    When i came to read this reply i read the thread title as Trial By Terror, which is probably more accurate :emoji_face_palm:
  6. Alvin

    Tuller / Trial By Error: The Crawley Chronicles, Resumed

    I suspect she operates under the "principle" If you can't dazzle them with brilliance, baffle them with bullshit. Reality won't cooperate with their psychological nonsense so distort reality to fit the lies.
  7. Alvin

    The Dopamine Imbalance Hypothesis of Fatigue in Multiple Sclerosis

    No brain power to read the study but raising dopamine is only a Dexedrine or Levodopa tablet away
  8. Alvin

    Tuller / Trial By Error: The Crawley Chronicles, Resumed

    Very well done :) The long version is very long, i already fried my brain on the short one so in future i'll take a stab at the long version :) Oh and something to point out, ethical scientists typically argue things based on the merits because we are right, but the other side will play dirty...
  9. Alvin

    Huntington’s breakthrough may stop disease

    That is insanely good news :) I hope they don't price it out of reach or destroy the life savings of sufferers.
  10. Alvin

    A randomised controlled trial of the monoaminergic stabiliser (-)-OSU6162 in treatment of ME/CFS (2017) Nilsson et al.

    I wonder if this drug would be superior to something like Selegiline or Rasagiline.
  11. Alvin

    Article: Traumatic Brain Injury Causes Intestinal Damage

    Agreed :cry: Since it would be unethical to perform this type of experiment in humans we use animal surrogates, with the knowledge that the data may not hold species to species but in the hope there are parallels as there often are. All that said i do not condone doing torturous treatments on...
  12. Alvin

    Article: “I was ready to give up on my life with ME ... but Perrin treatment miraculously changed everything”

    I find these likely coincidental spontaneous improvements attributed to unproven and likely sham treatment stories very annoying :emoji_face_palm:
  13. Alvin

    Selling Bad Therapy to Trauma Victims

    It basically seems to come down to science is failing our ideology so disregard it :emoji_face_palm: Funny that it never comes down to science is not backing us up, why is that, lets find out why and improve our processes. :emoji_face_palm:
  14. Alvin

    Selling Bad Therapy to Trauma Victims

    I don't have the energy to pick apart the multiple pieces of nonsense in that article so i'll just say its a perfect example of why the facepalm emoji is so necessary :emoji_face_palm:
  15. Alvin

    Menon - Mitochondrial Modifying Nutrients in Treating Chronic Fatigue Syndrome: A 16-week Open-Label Pilot Study

    Here is an example of using statistics to "prove" something, by playing with numbers one can prove opposites are correct https://projects.fivethirtyeight.com/p-hacking/
  16. Alvin

    Menon - Mitochondrial Modifying Nutrients in Treating Chronic Fatigue Syndrome: A 16-week Open-Label Pilot Study

    Technically i agree, and i do know a thing or two about statistics (i did in a previous life anyways), and suffice it to say 87 patients won't give you a 95% confidence interval :laugh: What i was getting at is this seems to be a ploy to make a quick buck by stacking numbers to make it so and a...
  17. Alvin

    Menon - Mitochondrial Modifying Nutrients in Treating Chronic Fatigue Syndrome: A 16-week Open-Label Pilot Study

    Bigger numbers are always nice but if there is no statistical significance for 87 patients i don't think 870 patients will fare much better, assuming they all have the same disease. Bigger numbers won't make something that doesn't work, work Fancy multi vitamin with a few things added. How much...
  18. Alvin

    NYT A Failure to Heal / What happens when a clinical trial fails?

    I've found its worth figuring out the mechanism, if something works can we determine why it works, because that can help us cut through any statistical questions and can hopefully lead to further treatment optimizations and hopefully even better future treatments. Hard to do for psychosomatic...
  19. Alvin

    Blog: Medical Research Council, Stephen Holgate, "The precision medicine revolution: putting the patient first"

    Indeed I have heard of a few instances where blood tests or genetic tests can determine if a medication will be tolerated or what doses to start with but this type of medicine is more star trek-ish then realistic so far. By the time the Enterprise is built i expect ME/CFS will have been cured :)...
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