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This guy was diagnosed with NAFLD. Being a chemical process engineer he wanted to find a cause and solution as all doctors he consulted could offer nothing. Reversed it, and is now very evangelical about low carb / keto. He was appalled by the quality of some of the scientific papers en...

When was the sampling done? Would it not have been useful to have testing done 24/48/72 hours later and compared? Or have i simply lost the plot? .....

There are also different types of B12. My daughter does tolerate methylcobalamin but some do not. If you have gut issues you may have issues with B12. It may simply feed a colony of bacteria. I know of some people taking B and multi vitamins by " patches" - similar to nicotine ones- this...

thanks @Esther12

No, on my to do list before the end of this month - will update thereafter

If someone has access can they provide link tobfollowing page- the following article on what is FII looks both relevant and interesting .

And you have to have both

That' s around what i get without ME with around 2-3 breaks in it. ...I have never been a good sleeper .

Perhaps worth a thread on its own. I think that for many there may have been ME symptoms previous to recognised onset just awaiting a trigger / or for gradual onset achieving critical mass . It might be interesting to see if there are general ones ..

My dad died of lung cancer. He had an all clear x ray , then 3-4 months later had another that showed lungs covered. My stepmum is a radiographer and was stunned at the difference in so short a time. He drank like a fish, smoked like a chimney and spent first 20 years of his career in...

Does this link to the ubiquinone transformation s in complex II and III, as some deaminmases have also been linked to immune function ?

Pre morning coffee - so this may be totally tangential - apologies in advance. As body senses CO2 and not oxygen, perhaps it is more of a CO2 / O2 balance issue? Would switch to anaerobic metabolism impact?

In a normal person, someone with a simple condition, yes. But i think , give this condition affects all systems, feedback loops may be " wired" differently to maintain function.

That one would also be an interesting one for male/female proportions

Would it have any link to issue with blood volume affecting oxygen levels?

Both authoref by Crawley

Given you are now a trustee(?), have been more severely affected previously, straddle the patient/ organisational divide , it seems strange that you were not aware of this . Had you at least the opportunity to comment on the info pre issue? If not then you may have a significantly bigger...

Adjuvent effect ? May be particularly important for vaccines which provide longer term protection and have a higher load - tetanus / HPV etc Status of female immune system function in childhood/ adolescence? Do we simply assume that it' s only in pregnancy that it modifies? ( Apologies in...

Thinking from the metabolic trap idea that other genes in the same function group may not compensate for mutations in others as has previously been assumed- what common genes linked to liver function might this apply to - high incidence, low penetration and substrate limiting? Would these...

Thanks @Trish . I really need to do some basic tech techniques!