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  1. Andy

    Brain FADE syndrome: the final common pathway of chronic inflammation in neurological disease, 2024, Khalid A. Hanafy

    Please could provide reference or references that show this? 40 years of biomedical small investigations from the 80s and 90s not being followed sufficiently followed by the BPS model then taking over, ignoring that evidence, and sucking up the majority of the funding - certainly I would not...
  2. Andy

    Earseeds, Acuseeds

    Not quite as bad, in theory Chalder should have the skills to be able to tell how bad her own work is.
  3. Andy

    Earseeds, Acuseeds

    Sigh, a well-meaning relative has sent me a link to the BBC News article about this, https://www.bbc.co.uk/news/uk-england-south-yorkshire-68028447 Now I have to find the right words to gently explain why, despite appreciating their intentions for sending this to me, I think the subject of the...
  4. Andy

    Repeated cold stress, an animal model for [FM], elicits proprioceptor-induced chronic pain with microglial activation in mice 2024 Wakatsuki et al

    Full title: Repeated cold stress, an animal model for fibromyalgia, elicits proprioceptor-induced chronic pain with microglial activation in mice [More dubious animal 'models'] Background Fibromyalgia is characterized by chronic pain, fatigue, and other somatic symptoms. We have recently...
  5. Andy

    The Netherlands ME/CFS Cohort and Biobank (NMCB) consortium

    I believe that they officially launched today. Website - https://nmcb.eu/ Twitter post, linking to the website, "We're proud to announce The Netherlands National Cohort and Biobank Consortia – an eight-year collaboration of Dutch research institutes, medical centers & patient organizations...
  6. Andy

    Earseeds, Acuseeds

    Why Dragon's Den's latest episode was so damaging While Dragon's Den viewers were still buzzing over the addition of newest honorary dragon Gary Neville, social media was also discussing the devastating impact Thursday night's show had on the disability community. ME (myalgic...
  7. Andy

    Persistent complement dysregulation with signs of thromboinflammation in active Long Covid, 2024, Boyman et al

    Abstract Long Covid is a debilitating condition of unknown etiology. We performed multimodal proteomics analyses of blood serum from COVID-19 patients followed up to 12 months after confirmed severe acute respiratory syndrome coronavirus 2 infection. Analysis of >6500 proteins in 268...
  8. Andy

    ‘The Lightning Process’ and chronic fatigue syndrome/myalgic encephalomyelitis, 2022, Vallings

    Redfox quotes part of the quote from this post, https://www.s4me.info/threads/%E2%80%98the-lightning-process%E2%80%99-and-chronic-fatigue-syndrome-myalgic-encephalomyelitis-2022-vallings.29760/#post-440868
  9. Andy

    Psychosocial conditions during school-age as determinants of long-term labour market attachment:... 2024 Virtanen et al

    Full title: Psychosocial conditions during school-age as determinants of long-term labour market attachment: a study of the Northern Swedish Cohort from the 1980s to the 2020s Abstract Background This study, conducted on a Swedish population cohort, explores how internalized (depressive and...
  10. Andy

    A biopsychosocial approach to persistent post-COVID-19 fatigue and cognitive complaints: ... 2024 Klinkhammer et al

    Full title: A biopsychosocial approach to persistent post-COVID-19 fatigue and cognitive complaints: results of the prospective multicenter NeNeSCo study Objective To evaluate whether psychological and social factors complement biomedical factors in understanding post-COVID-19 fatigue and...
  11. Andy

    YouTube videos: David Tuller on Tub Talks With Damon discussing ME/CFS and Long Covid, 2022,2024

    Gosh, almost two years since Dave's last bath... ;)
  12. Andy

    United Kingdom: ME Research UK (MERUK) News

    ME Research UK and Daphne Jackson Trust launch ME/CFS Fellowship Applications are invited for a three-year Daphne Jackson Fellowship co-sponsored by ME Research UK. The Fellowship is open to talented researchers with a PhD – likely in a life science e.g. biomedical sciences, whole organismal...
  13. Andy

    Neutrophil degranulation, endothelial and metabolic dysfunction in unvaccinated long COVID patients, 2024, Di Ciaula et al

    Abstract Background Long COVID symptoms are widely diffused and have a poorly understood pathophysiology, with possible involvement of inflammatory cytokines. Materials and Methods A prospective follow-up study involved 385 unvaccinated patients, started 1 month after SARS-CoV-2 infection and...
  14. Andy

    Review Role of Muscarinic Acetylcholine Receptors in Intestinal Epithelial Homeostasis: Insights for the Treatment of [IBD] 2023 Uwada et al

    Abstract Inflammatory bowel disease (IBD), which includes Crohn’s disease and ulcerative colitis, is an intestinal disorder that causes prolonged inflammation of the gastrointestinal tract. Currently, the etiology of IBD is not fully understood and treatments are insufficient to completely cure...
  15. Andy

    Review Impact of aerobic and resistance training on fatigue, quality of life, and physical activity in prostate cancer patients 2024 Nader et al

    Background: Prostate cancer (PCa) is a prevalent cancer with significant morbidity and mortality rates. In most cases, prostate cancer remains asymptomatic until advanced disease manifests with symptoms, such as benign prostate hyperplasia (BPH). Timely detection and better management have...
  16. Andy

    Review Beyond neurotransmission: acetylcholine in immunity and inflammation 2019 Cox et al

    Abstract Acetylcholine (ACh) is best known as a neurotransmitter and was the first such molecule identified. ACh signalling in the neuronal cholinergic system has long been known to regulate numerous biological processes (reviewed by Beckmann and Lips). In actuality, ACh is a ubiquitous...
  17. Andy

    Review nature reviews cardiology: Cardiovascular autonomic dysfunction in post-COVID-19 syndrome: a major health care burden, Fedorowski et al, 2024

    Peer review information Nature Reviews Cardiology thanks Svetlana Blitshteyn, David Goldstein and the other, anonymous, reviewer(s) for their contribution to the peer review of this work.
  18. Andy

    Review Experiences of people with multiple sclerosis and clinicians in using cognitive behavioural therapies for hidden symptoms: 2024 Feng et al

    Abstract Purpose Cognitive behavioural therapies (CBTs) are a standard of care for treatment of many ‘hidden symptoms’ in people with MS (PwMS), such as stress, depression, and fatigue. However, these interventions can vary widely in formatting and may not be tailored for PwMS. To optimize CBTs...
  19. Andy

    International: Science for ME social media posts

    Published papers thread for w/c 8th Jan. Facebook: https://www.facebook.com/sci4me/posts/pfbid02wKEdtNhqLCtdQ89WdwdZQegnXr3xoUo7KuxcZY7LPmEyPqUPobxkVuwVtmCM5sP7l Mastodon: https://med-mastodon.com/@s4me/111759505741210749
  20. Andy

    Assessing Functional Capacity in [ME/CFS]: A Patient Informed Questionnaire [FUNCAP], 2024, Sommerfelt et al

    A few comments, all with the proviso that I understand creating a good questionnaire is challenging. Given that the questionnaire says, "Items described include necessary activities to perform them. Example: "Going to a shop for groceries" includes getting dressed and as necessary travelling."...
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