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"A new wearable artificial intelligence (AI) technology could help to monitor the progression of movement disorders. In 2 studies, published in Nature Medicine, researchers demonstrate the potential of this new approach to increase the efficiency of clinical trials in Duchenne muscular...

Abstract Background Fibromyalgia patients who are exposed to extreme oxidative stress may face more severe clinical features or oxidative stress may be increased by the severity of the disease. Aim The purpose of these investigation were to determine serum paraoxonase activities (PON-1) and...

Abstract Background Older adults experience persistent symptoms post-COVID-19, termed as Long COVID, affecting their physical and mental health. This study aimed to evaluate the effects of Long COVID, level of physical activity, and functional decline on older adults’ health-related quality of...

Abstract Some patients develop multiple protracted sequelae after infection with SARS-CoV-2, collectively known as post-COVID syndrome or long COVID. To date, there is no evidence showing benefit of specific therapies for this condition, and patients likely resort to self-initiated therapies...

Introduction: Both public and scientific attention have shifted from the acute COVID-19 illness to the chronic disability experienced by a proportion of COVID-19 convalescents. Post COVID-19 condition, a term used for long-lasting symptoms after COVID-19, can affect individuals across all...

Full title: A randomized controlled trial protocol for persistent physical symptoms associated with indoor environment or chronic fatigue: Effectiveness of video-based functional case conceptualization and web-program for improving quality of life Introduction: Persistent physical symptoms...

Full title: The Cognitive and Behavioural Responses to Symptoms Questionnaire (CBRQ): Development, reliability and validity across several long-term conditions Abstract Objectives Cognitive and behavioural responses to symptoms can worsen or maintain the severity of symptoms across long-term...

Trial By Error: Double Talk on Mind-Body “Dualism”? "Proponents of the psychosomatic approach to ME and long Covid–as well as the broader range of so-called “functional” disorders and/or “medically unexplained symptoms”–routinely declare that those who disagree with them are engaging in what...

Abstract Objective Individuals after stroke are less active, experience more fatigue, and perform activities at a slower pace than peers with no impairments. These problems might be caused by an increased aerobic energy expenditure during daily tasks and a decreased aerobic capacity after...

"From the moment I called to make the appointment to the second I left the building, I was reminded, drip by drip, how sexual healthcare in this country is at best unwelcoming to disabled people, and at worst completely inaccessible. I just wanted the usual MOT – which we should all be getting...

• What is it? The Sunday closest to M.E. awareness day (12th May) has come to be known as Blue Sunday by the ME/CFS community after I held my first Tea Party For M.E. on that day in May 2013. I’m gearing up to my 11th annual event and you’re all invited. • When is it? Sunday 14th May. There’s...

Situations Vacant: Communications Officer, closes 1st Feb 2023. "With an increasing demand on core services, we are looking for a part-time, enthusiastic, responsible, and well-organised person to join the communications team. You will report directly to the head of communications and your...

Full title: Blood-brain barrier penetration of non-replicating SARS-CoV-2 and S1 Variants of Concern induce neuroinflammation which is accentuated in a mouse model of Alzheimer’s disease Abstract COVID-19 and especially Long COVID are associated with severe CNS symptoms and may place persons...

News in Brief posts for w/c 16th Jan. Facebook: https://www.facebook.com/sci4me/posts/pfbid0i6pPfGPGUnzTbrbvGyxQhzhxWZEJTDr5FyTyzjceJimtdpVSKDmimR2rJGvhFe92l Mastodon: https://botsin.space/@s4me_news/109734073380355159 and published papers thread. Facebook...

Merged thread Background & Aims The coronavirus disease 2019 (COVID-19) pandemic has affected populations, societies, and lives for more than 2 years. Long-term sequelae of COVID-19, collectively termed the postacute COVID-19 syndrome, are rapidly emerging across the globe. Here, we...

From their Facebook post, https://www.facebook.com/WalkforMEUK/posts/pfbid0sG1pka8rPmYRCtzyrfP4cstrCnpyb1TEnsqB18rfLqdnb6aPea5xNpqwgPKzvgSHl "Welcome to Walk for ME 2023! The original idea behind Walk for ME was that friends and family members did a sponsored walk on behalf of a loved one with...

Abstract Herpes simplex virus type 1 (HSV-1) is a ubiquitous human pathogen that can cause significant morbidity, primarily facial cold sores and herpes simplex encephalitis. Previous studies have shown that a variety of viruses can reprogram the metabolic profiles of host cells to facilitate...

Abstract Objective: To identify, summarise, and analyse comments on the core reporting guidelines for protocols of randomised trials (SPIRIT 2013) and for completed trials (CONSORT 2010), with special emphasis on suggestions for guideline modifications. Methods: We included documents written...

[Note: PEM here refers to "Patient Education Material"] 3.2. Terminology The most common terms used in patient education by survey respondents were Functional (71% of respondents), followed by specific syndrome names (Fibromyalgia 68%, Irritable Bowel Syndrome 64%, Chronic Fatigue Syndrome...

Highlights • We describe 5 main explanatory models for functional somatic symptoms. • Models are used flexibly by healthcare professionals to explain a range of symptoms. • They are used widely in patient education in treatment setting across in Europe. • The approaches described can engage...