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About stem cell therapy risks, stem cells from other people and babies https://www.pewtrusts.org/en/research-and-analysis/issue-briefs/2021/06/harms-linked-to-unapproved-stem-cell-interventions-highlight-need-for-greater-fda-enforcement

Thanks, @Hutan. Maybe I should posted this in the humor section.

Well, of course, what next, as I throw up my cake. The Mammoth Study, with a huge price tag. Old study, back in 2015. Here's the schtick which I found on the Versus-Arthritis.org site...

I just had a flashback to a pre-fibro beach camping trip. The sound of the lapping Pacific shore waves while I was trying to sleep ruined it for me. At the present, I'm blocking out the weekend street, busy beaver homeowner noise by shutting the window, enduring some extra heat rather than the...

p. 2 of the pdf--https://www.biorxiv.org/content/10.1101/2023.10.05.561025v1.full.pdf "Previous studies found overexpression of some HERV families in immune cells of ME/CFS (33) and FM (34) at the transcript level. However, the study and comprehension of HERV in ME/CFS and FM are still at...

https://academic.oup.com/painmedicine/article/23/6/1084/6443164?login=false I think this is not pay-walled. I am encouraged by this. Hope research is underway and it pans out.

There is science to it (https://evidencebasedbirth.com/sterile-water-injections-for-pain-relief-during-labor/ has a good explanation). As I now recall, you don't want to give opiates (especially in later stages of labor) because they can suppress the baby's breathing and slow the progress of...

I agree with you @Arnie Pye. I was wise-cracking--the powers that be can avoid the controversy (if there is one) of giving a one-time opiate. Here in the US, opiates are a dirty word. I don't know what the policy is in obstetrics these days.

Sterile water is cheaper than a drug, and no controversy, just placebo.

Critique/discussion of the Nature article (Distinguishing Features of Long Covid Identified Through Immune Profiling) Starts at 16:00 minutes in (episode 1048 of TWIV https://www.microbe.tv/twiv/).

Has he had his hearing tested with an audiologist? does he have hearing loss? I say this because with the more expensive hearing aids (I think), the audiologist can program a sort of remedy, which, in my case, completely extinguishes the problem. I don't notice any tinnitus when I have my...

Clinical trial registration info, including info on sham exercise and sham brain stimulation. https://classic.clinicaltrials.gov/ct2/show/NCT03371225?cond=fibromyalgia&cntry=US&state=US:MA&draw=2&rank=5

No comment.

Rapid test on day 2 after symptoms start; then test again 48hrs later. About 90% accuracy of detecting a positive.

How easy is the game of mix and match. Take CBT and match the list of cognitive distortions to any and every known category to man. Obtain an odds ratio of under 1.1 and call it an association when it is most likely artifact and certainly not clinically significant. Take pride in seeing your...

I heard dialysis patients complain of fatigue. Never did I hear anyone say: this or that improved my fatigue. I doubt they had the energy to get up and go for another "treatment" (ie massage, acupressure). Some wouldn't even bother to reach for a sniff from their flacon of tahitian vanilla on...

This opinion-review piece highlights the ongoing lack of meaningful FM research. Though it does point out the heterogeneity of the syndrome. It is really sad that it is common and very painful and disruptive to one's life and the science hasn't advanced much in 20 years.

One would like to think so @RedFox. However, the "novelty" of this virus plays havoc with our immune system, i.e. the second week of infection can result in a cytokine storm (if and when the oxygen saturation drops below 94). Impossible to know the answer to your question. Unless you have a...

Could be the reverse scenario. When you have constant pain inputs (as in FM), the somato-sensory apparatus in the brain becomes already primed for negativity: the experience of constant pain signals is a negatively charged status quo. This is why a high-pain day with FM means also a...

Recent trial of this SL form of muscle relaxant cyclobenzaprine (Flexeril) for FM. https://pubmed.ncbi.nlm.nih.gov/37165930/