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  1. Eddie

    Book Review: We Are Electric by Sally Adee, Allen&Unwin 2023

    Thank you for entertaining this discussion, there have been many interesting ideas. I think I understand what you are saying here. The many worlds hypothesis would be deterministic in the sense that the probabilities are set in accordance to our pre-chosen world. While quantum events appear...
  2. Eddie

    Book Review: We Are Electric by Sally Adee, Allen&Unwin 2023

    It does seem like Einstein remained unconvinced that quantum mechanics was a complete theory even if it makes accurate predictions. He did explicitly state that God does not play dice. Perhaps he would be more convinced by one of deterministic quantum theories that exist today. I think...
  3. Eddie

    How often is ME/CFS diagnosed in people who don't have it?

    I think what would be most useful is figuring out what percentage of people that meet ME/CFS criteria are later discovered to have another condition. In the NIH study at least a few of the dozen or so patients that made it through to the final screening were found to have other medical issues...
  4. Eddie

    Book Review: We Are Electric by Sally Adee, Allen&Unwin 2023

    I'm not convinced that preference is somewhere between determined and stochastic. An event that occurs must either have a reason for occurring or not. Even if certain probabilities are greater than others, that needs explaining and should back to something unknowably random or determined. The...
  5. Eddie

    Book Review: We Are Electric by Sally Adee, Allen&Unwin 2023

    Jonathan brought up a good point that its not just about the number of connections. Neurons have more signals that just open or close so there are probably many different components to complexity. Maybe silicone is limited in its ability to be complex in enough or the right ways. It could also...
  6. Eddie

    Book Review: We Are Electric by Sally Adee, Allen&Unwin 2023

    Even for random quantum events just because its uncertain to an observer doesn't mean its not determined. I don't think we know that if we rewound the clock, these quantum events wouldn't go the same way. And if it is truly random then there is still no agency anyways.
  7. Eddie

    Book Review: We Are Electric by Sally Adee, Allen&Unwin 2023

    Exactly, and I think consciousness is deterministic and based of the laws of physics. I think the main reason why many people think differently now is because the amount of resources we would need to know all the inputs is so many times greater than with a computer.
  8. Eddie

    Book Review: We Are Electric by Sally Adee, Allen&Unwin 2023

    I certainly don't, as I am not a biologist. I tend to assume that many other animals have some level of conscious experience though. I would argue that if an organism seems to react in a similar way to pain as a human does, then we should assume they are in some way experiencing that. It does...
  9. Eddie

    Book Review: We Are Electric by Sally Adee, Allen&Unwin 2023

    Thanks for the previous post, I thought it was very interesting. I just had a few questions; why do we think everything consists of the transfer of information and not say the transfer of energy? If everything consists of informing, I'm not sure why the concept of qualia seems to be unique to...
  10. Eddie

    Book Review: We Are Electric by Sally Adee, Allen&Unwin 2023

    We know how computers work at the fundamental level. But as programs become more complex, it becomes more and more difficult to know how the 1 and 0s comes together to produce the desired result. In programs that use large data sets, I think it would be almost impossible to go back and figure...
  11. Eddie

    Book Review: We Are Electric by Sally Adee, Allen&Unwin 2023

    If you showed someone from a thousand years ago that bits of rock can be organized in a way to carry out complex programs and answer all sorts of problems, they would probably think you had magic powers. Even now, we don't know how a computer runs complex programs, how all the individual...
  12. Eddie

    Monitoring Carotid Blood Flow Using In-Ear Wearable Device During Tilt-Table Testing, 2023, Hemantkumar Tripathi MD et al

    Looks like there are different modes. The real time mode measures every second but presumably uses more power. The website says 5 mins continuous monitoring uses 2% power which doesn't seem too bad.
  13. Eddie

    Brain and muscle chemistry in ME/CFS and long COVID: a 7T magnetic resonance spectroscopy study, 2025, Godlewska et al

    It could be that both viral infections and ME involve higher lactate levels in the brain. So I am not sure what that would rule out other than suggesting that perhaps they involve some of the same features. 24/25 subjects and controls seems pretty decent for this kind of study. Interesting...
  14. Eddie

    Needing to lie flat

    One other factor that I have not seen mentioned yet is "pooling" of blood in my hands and feet when upright. Especially in warm temperatures my feet and hands will become red/purple and feel somewhat swollen when standing. They also become extremely itchy and are a factor that causes me to sit...
  15. Eddie

    Novel brain SPECT imaging unravels abnormal cerebral perfusion in patients with POTS and cognitive dysfunction, 2025, Marie-Claire Seeley et al

    61% of POTS patients having a CBF value in the bottom 5% of the control reference values is an interesting result. I don't know much about SPECT but given others have had similar findings it seems like a plausible abnormality.
  16. Eddie

    Placebo effect discussion thread

    I don't think we know if there is an objective way to measure pain. If it is possible to produce AI that can feel pain then it could be measurable, but that is a little besides the point. I agree that the placebo could be due to expectations about treatment and reporting better outcomes due to...
  17. Eddie

    Placebo effect discussion thread

    If the placebo effect actually works then it should have a biological mechanism by which it works. If pain is the result of a signal in the brain that produces a negative experience, how does a placebo block those signals from being processed?
  18. Eddie

    Negative Association of [GWI] Symptomatology with Predicted Binding Affinity of Anthrax Vaccine Antigen to [HLA II molecules], 2025, James et al

    If you removed the one outlier with a very high GWI score and the two individuals with more than 150 hits, I 'm guessing the correlation would only be very weak. There could still be an association, but it would have been more convincing if the trend wasn't driven by a handful of individuals.
  19. Eddie

    News From Jarred Younger / Neuroinflammation, Pain, and Fatigue Laboratory at UAB, From Aug 2020

    Has there been any updates on Younger's leukocyte tracking scan or his PET and MRI scans in ME/CFS patients? He mentioned the PET scan should be done in 2024 but it seems like its been a while since he's given any new info.
  20. Eddie

    What do we mean by a diagnosis like ME/CFS?

    To me it is less about predicting cause and effect and more to do with convenience in conveying meaning. There are very broad labels that don't tell us much at all about an individual but apply to a wide range of the population. There are also very focused labels that tell us a much greater...
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