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    Skin crawling/formication

    I go wonder if this is a hormonal symptom that may indicate issues with liver? Synthesis and bio transformation of many steroid hormones is part of liver' s job, and the liver ( I read somewhere) does a lot of housekeeping at night when we are supposed to be asleep. There seems to be an issue...
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    Esther Crawley (2019) Physical activity patterns among children and adolescents with mild-to-moderate CFS / ME [baseline accelerometer MAGENTA data]

    Whenever did objective evidence get in the way of a well reinforced poorly defined construct....particularly one with an asymmetric power balance and a sprinkling of messiah complex
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    Novel insights of overtraining syndrome discovered from the EROS study, 2019, Cadegiani and Elias Kater

    Can we put the Nottingham exercise researchers in touch with these ones?
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    BMJ Archives of Diseases in Childhood: ''Editor’s note on correction to Crawley et al. (2018)'', 2019, Nick Brown. (SMILE LP Trial)

    My daughter's favourite retort to those who think paralympic athletes reflect the aspirational goal for every disabled person - "so you're modelling yourself on Usain Bolt?"
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    MEA Website Survey: Physiotherapy and ME | 02 July 2019

    Yes they are trained in massage, but this tends to be either for conditions that have a noted benefit ( not really part of the ME playbook) , or from a private physio. A few physios here work part time in NHS and have private businesses . Massage was beneficial for my daughter but took too...
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    BMJ Archives of Diseases in Childhood: ''Editor’s note on correction to Crawley et al. (2018)'', 2019, Nick Brown. (SMILE LP Trial)

    Perhaps it was an assumption that school records would be made available ( assumption of a lot of things underwrites world view here) Or perhaps it's the impact of GDPR kicking in between start and end. Or both?
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    Mad Cow Disease: The Great British Beef Scandal

    The problem with pesticides is that the acceptable levels are based on individual pesticides. From sowing to crop there are a multitude of chemicals used- the combination and its effects seems to be under researched. For example potatoes locally can be sprayed with different chemicals up to 32...
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    Weighted blankets

    Bamboo is good for moisture control. My daughter's s memory foam neck pillow has a bamboo casing which seems to help. Wool is also great at " wicking". But perhaps given weight issues, better for winter.
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    Study finds psychiatric diagnosis to be ‘scientifically meaningless’

    Very much so. My daughter had cbt via CAHMS for anxiety. The second session was a fishing trip for early childhood trauma which she found very upsetting. The therapist simply could not accept what she was telling them .CBT was a disaster and left her no better for it and thinking she had "...
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    Post-Exertional Malaise Is Associated with Hypermetabolism, Hypoacetylation and Purine Metabolism Deregulation in ME/CFS Cases, 2019, McGregor et al

    There were a few threads re BCAAs at the other place. Many used them for "PEM busting ability"
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    BMJ Archives of Diseases in Childhood: ''Editor’s note on correction to Crawley et al. (2018)'', 2019, Nick Brown. (SMILE LP Trial)

    For a population group who are supposed to benefit from higher levels of protection, when it comes to paediatrics, careers seem to trump the health and wellbeing of children. Has there been a precedent in English law along the lines of Montgomery v South Lanarkshire Council? In light of...
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    Weighted blankets

    Knitted cotton blanket, some are patterned so will have weight while still having lighter areas ( maybe not so warm?)
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    JAMA -"Advances in understanding the Pathophysiology of Chronic Fatigue Syndrome" by Anthony Komaroff

    Don't t despair. Although I feel that there are many routes to the same end state, there will be common pathways which may help define subsets. I think we are beginning to scratch the surface as the technology now exists and is evolving to enable scientists to dig a bit deeper. If we can...
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    ME Epidemiology - prevalence and peak ages of onset

    I wish I had a clue. Flinging a few things in perhaps testosterone drops off a cliff for some rather than starts gradually. That the lack of cholesterol in diets precludes productions of sufficient pregnenolone Impact of pesticides on hormonal synthesis - most pesticide safety use...
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    ME Epidemiology - prevalence and peak ages of onset

    Testosterone starts dropping in 30s. Same biochemical impacts hold re synthesis pathways, cofactors and deficiencies. Perhaps the low cholesterol diet is responsible for other impacts other than the rise of T2 diabetes.
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    MicroRNAs as biomarkers of pain intensity in patients with chronic fatigue syndrome. Al-Rawaf (2019)

    I would agree I would agree re pain tolerance. My daughter finds it difficult to compare pain / " meh face" scores on a diary app she has as her pain tolerance has changed over time, probably as the nature and degree of pain has changed. People become accustomed to a background pain level...
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