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  1. Andy

    Well-known, famous people with ME/CFS (public thread)

    Martine McCutcheon still affected by illness. "In her caption, Martine spoke candidly about her struggles with chronic fatigue syndrome and fibromyalgia – a condition which causes widespread pain and extreme tiredness." "She penned: "What A GREAT Gatsby Night to remember! I haven't been out...
  2. Andy

    Review Overall comorbidities in functional neurological disorder: A narrative review 2023 Carle-Toulemonde et al

    Introduction The importance to assess and include the frequent comorbidities in the personalised care management plan of patients with functional neurological disorders (FND) has arisen through the years. FND patients are not only complaining from motor and/or sensory symptoms. They also report...
  3. Andy

    Functional tics: expanding the phenotypes of functional movement disorders? 2023 Cavanna et al

    Background Until the outbreak reported during the COVID-19 pandemic, functional tics were considered to be a relatively rare clinical phenotype, as opposed to other functional movement disorders such as functional tremor and dystonia. In order to better characterise this phenotype, we compared...
  4. Andy

    One-session treatment compared with multisession CBT in children aged 7 16 years with specific phobias: the ASPECT non-inferiority RCT, 2023, Wright

    Abstract Background Up to 10% of children and young people have a specific phobia that can significantly affect their mental health, development and daily functioning. Cognitive–behavioural therapy-based interventions remain the dominant treatment, but limitations to their provision warrant...
  5. Andy

    Long-term clinical & cost-effectiveness of a therapist-supported online remote behavioural intervention for tics in children & adolescents 2023 Hollis

    Full title: Long-term clinical and cost-effectiveness of a therapist-supported online remote behavioural intervention for tics in children and adolescents: extended 12- and 18-month follow-up of a single-blind randomised controlled trial Background Little is known about the long-term...
  6. Andy

    Review A systematic review and meta-analysis of urinary biomarkers in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), 2023, Taccori et al

    Background Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a multifactorial illness that affects many body systems including the immune, nervous, endocrine, cardiovascular, and urinary systems. There is currently no universal diagnostic marker or targeted treatment for ME/CFS...
  7. Andy

    Article: Science: Is exercise actually good for the brain?

    "There are plenty of reasons to get off your duff and exercise—but is improving your brain one of them? The U.S. Centers for Disease Control and Prevention touts exercise as a way to “boost brain health,” while the World Health Organization suggests that about 2 hours of moderate activity or 75...
  8. Andy

    Immune resilience despite inflammatory stress promotes longevity and favorable health outcomes including resistance to infection 2023 Ahuja et al

    Why Some People Get Sick More Often "Everyone gets sick. Despite all the vegetables we eat or vitamins we gulp down, sooner or later pathogens such as viruses and harmful bacteria infiltrate our bodies, and we need to take a time-out. We sit back and let our immune system do its job. But when...
  9. Andy

    Immune resilience despite inflammatory stress promotes longevity and favorable health outcomes including resistance to infection 2023 Ahuja et al

    Abstract Some people remain healthier throughout life than others but the underlying reasons are poorly understood. Here we hypothesize this advantage is attributable in part to optimal immune resilience (IR), defined as the capacity to preserve and/or rapidly restore immune functions that...
  10. Andy

    Guide: Involving People with ME and Other Energy Limiting Conditions, by the World ME Alliance

    I've posted before reading this, so have no opinion on it yet, although at the least I think the topic is an important one.
  11. Andy

    Guide: Involving People with ME and Other Energy Limiting Conditions, by the World ME Alliance

    The World ME Alliance, a global coalition of organisations advocating for those affected by Myalgic Encephalomyelitis (ME), is proud to announce the release of a new guide. This comprehensive resource, titled “Involving People with ME and Other Energy Limiting Conditions,” aims to promote...
  12. Andy

    UK: New £14 million investment targets rare diseases

    A new platform bringing together UK strengths in rare diseases research to improve diagnosis and treatment through better understanding of the disease. The UK Rare Disease Research Platform has been established with a £14 million investment over five years by the Medical Research Council (MRC)...
  13. Andy

    The neuroimaging evidence of brain abnormalities in functional movement disorders, 2021, Sasikumar and Strafella

    So when properly investigated physical abnormalities are found in people diagnosed with a functional condition, and somehow that supports the idea of functional conditions, rather than highlighting how flawed it is?
  14. Andy

    Closed UK: DecodeME updates, was recruitment thread.

    In the UK there is, https://bepartofresearch.nihr.ac.uk/, but awareness of it is low.
  15. Andy

    Typing myalgic encephalomyelitis by infection at onset: A DecodeME study, 2023, Bretherick et al

    Revised version is available, following peer reviewers comments, https://openresearch.nihr.ac.uk/articles/3-20/v2 "Amendments from Version 1 The revised manuscript has benefited greatly from the reviewers’ constructive suggestions. In response, the study’s main aim has been made explicit in...
  16. Andy

    Functional Neurological Disorder (FND) - articles, social media and discussion

    Jon Stone has had an editorial published titled "Functional neurological disorder: Past, present and future", paywalled, https://www.sciencedirect.com/science/article/abs/pii/S0013700623000908, with no abstract available. What is shown is "Acknowledgments This special FND issue of L'Encéphale...
  17. Andy

    Review Mechanisms and Severity of Exercise Intolerance Following COVID-19 and Similar Viral Infections: A Comparative Review 2023 Weldon et al

    What a mess of an article. Just two examples "Post-Infection Fatigue Syndrome (PIFS) As discussed above, there is an acute decrease in strength and endurance immediately following a febrile illness. However, in some patients, symptoms may persist and result in chronic exercise intolerance and...
  18. Andy

    Review Mechanisms and Severity of Exercise Intolerance Following COVID-19 and Similar Viral Infections: A Comparative Review 2023 Weldon et al

    Abstract Approximately 19% of the population is suffering from “Long COVID”, also known as post-acute sequelae of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (PASC), which often results in exercise intolerance. As COVID infections continue to be common, studying the long-term...
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