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  1. Andy

    Cardiopulmonary Profiling of Athletes with Post-Exertional Malaise after COVID-19 Infection—A Single-Center Experience, 2023, Wernhart et al

    Abstract Background: Cardiopulmonary exercise testing (CPET) has been suggested by the European Society of Cardiology (ESC) for assessing the exercise limitations of apparently healthy individuals, but data on elite athletes regarding this test are scarce. Methods: We analyzed CPET in elite...
  2. Andy

    Association of digital measures and self-reported fatigue: a remote observational study in healthy participants and participants with... 2023 Rao

    Full title: Association of digital measures and self-reported fatigue: a remote observational study in healthy participants and participants with chronic inflammatory rheumatic disease Background: Fatigue is a subjective, complex and multi-faceted phenomenon, commonly experienced as tiredness...
  3. Andy

    Review An understanding of the immune dysfunction in susceptible people who develop the post-viral fatigue syndromes ME/CFS and Long Covid, 2023 Walker et al

    Abstract Viral infection in most people results in a transient immune/inflammatory response resulting in elimination of the virus and recovery where the immune system returns to that of the pre-infectious state. In susceptible people by contrast there is a transition from an acute immune...
  4. Andy

    Association analysis between symptomology and herpesvirus IgG antibody concentrations in (ME/CFS) and MS, 2023, Domingues et al

    Abstract Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and multiple sclerosis (MS) are two complex and multifactorial diseases whose patients experience persistent fatigue, cognitive impairment, among other shared symptoms. The onset of these diseases has also been linked to acute...
  5. Andy

    Longitudinal gut microbiome analyses and blooms of pathogenic strains during lupus disease flares, 2023, Azzouz et al

    Objective Whereas genetic susceptibility for systemic lupus erythematosus (SLE) has been well explored, the triggers for clinical disease flares remain elusive. To investigate relationships between microbiota community resilience and disease activity, we performed the first longitudinal...
  6. Andy

    Mood Symptoms and CFS due to Relapsing-Remitting Multiple Sclerosis Are Associated with Immune Activation and Aberrations in the Erythron 2023,Almulla

    "All the individuals were free of (lifetime and current) axis-1 neuropsychiatric disorders including a major depressive episode, schizophrenia, bipolar disorder, psycho-organic disorders, substance-use disorders (except nicotine dependence), medical disorders including chronic fatigue syndrome...
  7. Andy

    Understanding the Experience and Impacts of Brain Fog in Chronic Pain: A Scoping Review 2023 Dass et al

    Introduction Approximately 15% to 40% of persons with chronic pain as a primary disorder experience brain fog. Prior research has investigated the etiology of “brain fog” in conditions in which pain presents as a key feature (e.g., fibromyalgia). However, it remains understudied in the context...
  8. Andy

    American Family Physician: Patient Information: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: How to Help Yourself 2023

    Myalgic encephalomyelitis (my-AL-gic en-SEH-fuhlow-MY-uh-LIE-tus)/chronic fatigue syndrome (ME/CFS) is a chronic, severe, possibly disabling disorder. It can cause inflammatory, neurologic, immune, and metabolic problems that are not well understood. More at...
  9. Andy

    American Family Physician: Fatigue in Adults: Evaluation and Management, 2023, Latimer et al

    Fatigue is among the top 10 reasons patients visit primary care offices, and it significantly affects patients' well-being and occupational safety. A comprehensive history and cardiopulmonary, neurologic, and skin examinations help guide the workup and diagnosis. Fatigue can be classified as...
  10. Andy

    Assessing fatigue and sleep in chronic diseases using physiological signals from wearables: A pilot study 2022 Antikainen et al

    Article from one of the study centres. Wearable technologies can reliably measure fatigue and disturbed sleep in chronic disease https://www.newcastle-hospitals.nhs.uk/news/wearable-technologies-can-reliably-measure-fatigue-and-disturbed-sleep-in-chronic-disease/
  11. Andy

    Assessing fatigue and sleep in chronic diseases using physiological signals from wearables: A pilot study 2022 Antikainen et al

    "Participants were excluded if they had certain comorbidities like major sleep disorders, chronic fatigue syndrome, respiratory, cardiovascular or metabolic disorders or physical traumas with hospitalization in the past 3 months, diagnosis of cancer in the past 3 years, major psychiatric...
  12. Andy

    Assessing fatigue and sleep in chronic diseases using physiological signals from wearables: A pilot study 2022 Antikainen et al

    Problems with fatigue and sleep are highly prevalent in patients with chronic diseases and often rated among the most disabling symptoms, impairing their activities of daily living and the health-related quality of life (HRQoL). Currently, they are evaluated primarily via Patient Reported...
  13. Andy

    Anomalies in the review process and interpretation of the evidence in the NICE guideline for (CFS & ME), 2023, White et al

    I believe that sending out a press release given to them to their media contacts is their regular level of support, so I wouldn't be surprised if they had (they were interested in doing so for the launch of DecodeME). I was more referring to the lack of a 'roundup' or 'rapid reaction' which they...
  14. Andy

    Anomalies in the review process and interpretation of the evidence in the NICE guideline for (CFS & ME), 2023, White et al

    Maybe, but I would have thought that if they wanted to support the awareness of this opinion piece then they could have found a couple of people to speak in favour of it. Or perhaps there was no attempt made to get them interested in it, whatever the case it's unlikely that we will ever know for...
  15. Andy

    Review Prevalence of Neuroradiological Abnormalities in First-Episode Psychosis A Systematic Review and Meta-analysis 2023 Blackman et al

    Make brain scans routine for new psychosis patients, experts say Study finds MRI scans led to different diagnosis or change in care in 6% of cases https://www.theguardian.com/science/2023/jul/12/make-brain-scans-routine-for-new-psychosis-patients-experts-say
  16. Andy

    Review Prevalence of Neuroradiological Abnormalities in First-Episode Psychosis A Systematic Review and Meta-analysis 2023 Blackman et al

    Key Points Question How common are neuroradiological abnormalities in first-episode psychosis? Findings In this systematic review and meta-analysis, we found approximately 6% of patients with first-episode psychosis had an abnormality that required a change in clinical management. The number...
  17. Andy

    Anomalies in the review process and interpretation of the evidence in the NICE guideline for (CFS & ME), 2023, White et al

    MEAction UK’s Response To The Guardian Article 11 July 2023 https://www.meaction.net/2023/07/11/meaction-uks-response-to-the-guardian-article-11-july-2023/
  18. Andy

    Review Nutrient Therapy for the Improvement of Fatigue Symptoms 2023 Barnish et al

    Abstract Fatigue, characterised by lack of energy, mental exhaustion and poor muscle endurance which do not recover following a period of rest, is a common characteristic symptom of several conditions and negatively impacts the quality of life of those affected. Fatigue is often a symptom of...
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