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  1. Mij

    Trial Report RESTORE ME: A RCT of Oxaloacetate for Improving Fatigue in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS), 2024, Cash et al

    Ok, so is food grade considered the same as pharmaceutical grade that falls under the same classification as a drug?
  2. Mij

    Trial Report RESTORE ME: A RCT of Oxaloacetate for Improving Fatigue in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS), 2024, Cash et al

    I posted my results on the other thread. My levels were very low. They are referring to the supplement as 'medical food grade'. What does that mean exactly? Here we have clinical trials using Anhydrous Enol-oxaloacetate for brain function fatigue in cancer patients. I'm pretty sure...
  3. Mij

    Dangerous exercise: lessons learned from dysregulated inflammatory responses to physical activity, 2007, Dan Michael Copper et al

    What is clear from the existence of dangerous exercise is that the immune responses caused by exercise are real and robust. Like pharmaceutical therapies, prescribing exercise as therapy, an activity that is gaining in acceptance throughout the medical community, must be predicated on...
  4. Mij

    Dangerous exercise: lessons learned from dysregulated inflammatory responses to physical activity, 2007, Dan Michael Copper et al

    Abstract Exercise elicits an immunological “danger” type of stress and inflammatory response that, on occasion, becomes dysregulated and detrimental to health. Examples include anaphylaxis, exercise-induced asthma, overuse syndromes, and exacerbation of intercurrent illnesses. In dangerous...
  5. Mij

    Was there a gap between trigger and onset of your ME/CFS?

    Age of onset and gradual onset with no known infection would make it difficult to pin point. Also, middle aged women who enter early menopause might have difficulty distinguishing ME onset. Drops in hormones and hormonal imbalances can bring on orthostatic intolerance, physical and...
  6. Mij

    UK :Oxford researchers secure funding for world's first ovarian cancer prevention vaccine

    We can now envision an end to cervical cancer. A landmark study yields zero cases in women who got the HPV vaccine at a young age. But obstacles remain, including misinformation. LINK I wonder if they'll be able to develop a vaccine for endometrial cancer. It affects mostly menopausal women...
  7. Mij

    UK :Oxford researchers secure funding for world's first ovarian cancer prevention vaccine

    Researchers have been awarded funding from Cancer Research UK to create the world’s first vaccine to prevent ovarian cancer. Scientists at the University of Oxford are designing OvarianVax, a vaccine which teaches the immune system to recognise and attack the earliest stages of ovarian cancer...
  8. Mij

    The science of craniocervical instability and other spinal issues and their possible connection with ME/CFS - discussion thread

    The CCI study that Michael VanElzakker is recruiting for https://www.youtube.com/clip/UgkxEujY3nxq-JOA_VuGFaFKUjhNaJRxMARj
  9. Mij

    Hypothyroidism, 2024, Peter N Taylor, PhD et al

    Summary Hypothyroidism, the deficiency of thyroid hormone, is a common condition worldwide. It affects almost all body systems and has a wide variety of clinical presentations from being asymptomatic to, in rare cases, life threatening. The classic symptoms of hypothyroidism include fatigue...
  10. Mij

    Was there a gap between trigger and onset of your ME/CFS?

    I didn't answer the poll because the options don't describe my experience. I had a sudden viral onset that started with intense vertigo one morning. The vertigo went away after 3 days. I was vaccinated 3 weeks later (tetanus, rubella and tested for HepB). I felt 'ok' and was able to...
  11. Mij

    The science of craniocervical instability and other spinal issues and their possible connection with ME/CFS - discussion thread

    Point 50. PEM has a headache as a very prominent feature which may be primary or amplified Never
  12. Mij

    The science of craniocervical instability and other spinal issues and their possible connection with ME/CFS - discussion thread

    Point 61. Keep in mind traction can worsen symptoms. The change in the structure is not always a positive and can trigger PEM
  13. Mij

    Post-COVID-19 condition—Clinical phenotyping in practice, 2024, Karen Humkamp et al

    Abstract Background The high number and clinical heterogeneity of neurological impairments in patients with a post-COVID-19 condition (PCC) poses a challenge for outpatient care. Objective Our aim was to evaluate the applicability of the proposed subtypes according to the guidelines...
  14. Mij

    Needing to lie flat

    This is one of the studies where NASA put subjects in a 6° head-down tilt position. Do you mean lifting the whole bed on the head side has to include the chest area in order to work?
  15. Mij

    Paul Garner on Long Covid and ME/CFS - BMJ articles and other media.

    Post-exertional malaise best understood as a functional brain aberration, so research on brain neuronal networks needed-causal link with peripheral pathophysiology like muscle cell function/mitoch likely to reveal little
  16. Mij

    UK:Letter to all clinicians and services from the CPCS Professional Society

    Note: Professor Sivan is a signatory on the CPCS letter and works with Elaros ME Association: Professor Manoj Sivan to develop new protocol for #dysautonomia in #MECFS and #LongCovid The #MEAssociation is delighted to announce that a grant has been awarded from the Ramsay Research Fund to...
  17. Mij

    Covid-19 vaccines and vaccinations

    Action: things you can do to advocate for access to Novavax in Canada https://neednovavax.substack.com/
  18. Mij

    News from Canada

    Dr. Isaac Bogoch infectious disease doctor feeling uncomfortable while being schooled by astute Kwame McKenzie about Long Covid and post-infectious illnesss.
  19. Mij

    Does one biopsy cut it? Human muscle fiber composition variability using repeated biopsies..., 2024, van de Casteele et al

    Full Title: Does one biopsy cut it? Revisiting human muscle fiber type composition variability using repeated biopsies in the vastus lateralis and gastrocnemius medialis, 2024, Freek Van de Casteele et al Abstract Human skeletal muscle fiber type composition varies greatly along the muscle...
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