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Abstract Background The complex effects of Long-COVID, a syndrome marked by enduring symptoms after COVID-19 infection, with an emphasis on patients’ differing degrees of fibro fatigue (FF). Electrolyte disturbances may affect the severity of FF and may be used as a predictive tool for severe FF...

“The fibrin immunotherapy can be tested as part of a multipronged approach, along with prevention and vaccination, to reduce adverse health outcomes from long COVID.” A humanized version of Akassoglou’s first-in-class fibrin-targeting immunotherapy is already in Phase 1 safety and tolerability...

Abstract Life-threatening thrombotic events and neurological symptoms are prevalent in COVID-19 and are persistent in patients with long COVID experiencing post-acute sequelae of SARS-CoV-2 infection1,2,3,4. Despite the clinical evidence1,5,6,7, the underlying mechanisms of coagulopathy in...

PaxMedica Reports First Patient Treated with PAX-101(Suramin) for Fatal African Sleeping Sickness Infection Howard Weisman, CEO of PaxMedica, commented, "This first use of PAX-101 to treat a critically ill patient with Stage 1 HAT infection is an important milestone for the company following...

I've heard of pwME who experience internal tremors as well.

Despite the umbrella term that is used for it, Long COVID is “not really one disease,” says Krumholz. Internal tremors may be indicating one of the subtypes of this condition, with implications for treatment. Krumholz hopes that identifying the various symptoms of Long COVID will help...

Abstract The near-infrared spectroscopy (NIRS) vascular occlusion test (VOT) assesses microvascular reperfusion. Two strategies have been employed to quantify reperfusion following reactive hyperemia, but it is unclear if both yield similar results when comparing biological sex. Purpose...

Primarily, measuring pH changes and O2 consumption are just proxies for ATP production, and not a direct measurement. Other metabolic events or perturbations that affect pH and O2 use will also be interpreted as ATP consumption. Importantly, the Seahorse system is limited to cell culture...

Significance Adenosine triphosphate (ATP) is a key metabolite necessary for cellular life. Here, we develop a next-generation genetically encoded ratiometric fluorescent ATP sensor that allows subcellular tracking of ATP levels in living cells. The large dynamic range makes it possible to follow...

Dr. Anthony Fauci, former director of the National Institute of Allergy and Infectious Diseases, is recovering at home after being hospitalized with West Nile virus, a spokesperson said. LINK

Merged thread Man tests positive for monkeypox, COVID and HIV after holiday to Spain A 36-year-old patient in Italy returned from holiday in Spain and later presented with a series of symptoms that led doctors to carry out a series of tests. They found he was the first patient so far...

Abstract The use of generic specialty medications amongst individuals with multiple sclerosis (MS) has expanded due to an increase in the number of available agents. We describe a woman who was denied continued use of brand name teriflunomide (AubagioⓇ), despite being clinically stable for 2.5...

Abstract Neuroimaging studies have indicated that altered cerebral blood flow (CBF) was associated with the long-term symptoms of postacute sequelae of SARS-CoV-2 infection (PASC), also known as “long COVID”. COVID-19 and long COVID were found to be strongly associated with host gene expression...

Though the United States may be past the peak of its latest COVID-19 surge, federal health officials are eying ways to reduce the spread of the virus over colder months and the holiday season, including a relaunch of free COVID tests by mail. LINK A note about vaccine timing. We should note...

The systemic capillary leak syndrome following COVID-19 vaccine LINK

Could be that my diet is lacking in iodine considering I add sea salt to foods for the last 25yrs which doesn't contain iodine like regular salt.

Do all people with OI have low blood pressure? I don't, but I do feel somewhat more relaxed when I eat sea veggies which are full of electrolyte minerals, such as calcium, magnesium, sodium, and potassium.

Key Points Question What prolonged symptoms experienced by youth are most associated with SARS-CoV-2 infection? Findings Among 5367 participants in the RECOVER-Pediatrics cohort study, 14 symptoms in both school-age children (6-11 years) and adolescents (12-17 years) were more common in...

Epigenetic patterns, accelerated biological aging, and enhanced epigenetic: drift detected 6 months following COVID-19 infection: insights from a genome-wide DNA methylation study, 2024, Calzari Luciano, Dragani Davide Fernando et al Abstract Background The epigenetic status of patients 6-month...

Abstract Our study investigates the persistent cardiovascular symptoms observed in individuals long after contracting SARS-CoV-2, a condition commonly referred to as ?Long COVID?, which has significantly affected millions globally. We meticulously describe the cardiovascular outcomes in five...