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    Weird NHS ME clinic referral form

    Wow that would be expensive !
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    Weird NHS ME clinic referral form

    When I attended a CFS clinic for diagnosis (2014) and then a 12 month “course of treatment” I had to fill in a big questionnaire and attend a group session (of around 15 people) before I got the 121 sessions with the OH therapist. I don’t recall ever being asked whether I thought my illness was...
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    Dissecting the nature of post-exertional malaise, Hartle et al, 2021

    Almost certainly, they have conditioned the recipients of the questionnaires before they asked the questions and then muddled the results together to get their findings. I suspect there is quite a variance within the responses in the description of PEM and they have contrived some of the...
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    Dissecting the nature of post-exertional malaise, Hartle et al, 2021

    Only 150 people completing the questionnaire seems a bit light and the criteria for recruitment a bit loose? also the use of open ended questions is good for exploration but to then group and recode comments and apply statistics...not so much ...this is mixing methods in my book and introduces...
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    Covid-19 vaccination experiences

    Also heard this...Mrs sloth had no reaction at all, her sister was in bed for two days and is still struggling 10 days later ...both having AZ
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    Potential role of microbiome in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME), 2020, Lupo

    What a waste of time...some people with CFS had different poo than some other people...this tells us very little I’m afraid. Especially at the genus level. The fact that they are talking about leaky gut is a red flag for me...trash upon trash. classic end here caveating the whole thing ....not...
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    Who is Simon Wessely?

    Well the publicity machine is out in force
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    ME/CFS SKeptic: A new blog series on the dark history of psychosomatic medicine

    I think it would be interesting to work out what factors are at play that make medical staff want to adopt the psychosomatic dustbin option so readily. Is it because they are in a position of power; is it triage mentality gone mad? Perhaps it is conditioning from their training that it is their...
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    Physical, cognitive and mental health impacts of COVID-19 following hospitalisation: a multi-centre prospective cohort study, 2021, Evans et al.

    Moved post https://www.medrxiv.org/content/10.1101/2021.03.22.21254057v1 Abstract Background The impact of COVID-19 on physical and mental health, and employment following hospitalisation is poorly understood. Methods PHOSP-COVID is a multi-centre, UK, observational study of adults...
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    Breathlessness and air hunger in ME/CFS

    I think for me this feeling mostly comes with high heart rate. It feels like being out of breath but I wouldn’t say I’m panting or gasping for air but it feels the same if that makes any sense at all. I had to answer the phone the other day and then take a 2 flight of stairs trip to the...
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    Once-Weekly Semaglutide in Adults with Overweight or Obesity, 2021, Wilding et al

    I disagree with the term “addiction”, far too misleading IMO, but I agree with the inflammation part. rather than addiction, I would call it satiety imbalance. I agree that McDonald’s is partly responsible...you only have to look at the growth in emerging markets to see a correlation. However...
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    Once-Weekly Semaglutide in Adults with Overweight or Obesity, 2021, Wilding et al

    The timing of obesity is much much later than the 1950’s (in fact in the EU when additives were starting to be actively removed) 1980’s on wards. In terms of type II diabetes it is later still (shows a rapid upturn from the late 1990’s) in terms of additives the attached that appeared in...
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    Once-Weekly Semaglutide in Adults with Overweight or Obesity, 2021, Wilding et al

    Well the main problem is that a fizzy drink or chicken nugget is not harmful if eaten as part of a balanced diet. It’s the quantity eaten and balance in the diet that’s harmful, so you can’t draw parallels with tobacco or prescription drugs. Prescribing food is unrealistic for all the reasons...
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    Once-Weekly Semaglutide in Adults with Overweight or Obesity, 2021, Wilding et al

    Yes, my point was relating to the amount of shelf space, which is directly related to how many units are sold each week and the replenishment of shelf gaps twice a day. So to use your example if there is stock on shelf of wholemeal flour and it’s there when you come to buy it (pandemics aside)...
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    Once-Weekly Semaglutide in Adults with Overweight or Obesity, 2021, Wilding et al

    The space dedicated in store is directly related to the consumption of the goods not the other way around. Every transaction at the till goes to range reviews via EPOS (till point data) and each item will have a weekly rate of sale which is monitored weekly if not daily by the category...
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    Once-Weekly Semaglutide in Adults with Overweight or Obesity, 2021, Wilding et al

    Obesity is mainly a product of food prices vs income ...availability has something to do with it, as has the fall in manual labouring jobs but price is the main one. https://www.bbc.co.uk/news/business-45559594 Fresh fruit and veg proportionately though now cost more. Automation has driven...
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    The course of the illness for ME patients in Norway, 2021, Schei and Angelsen

    I’m not sure if this is relevant, but there is presumably an artefact due to average age of onset? I think PWME should have a cluster around the over 40’s (if I’m remembering rightly). If that is so then we know that there are spikes in the birth rate and country populations in general. I...
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    Once-Weekly Semaglutide in Adults with Overweight or Obesity, 2021, Wilding et al

    Yes I think this could be possible. To access the domestic market though it would need to come down quite a bit (bearing in mind the obesity crisis is heavily skewed to the poorest in society). Not sure but €30-100 per month feels more realistic than €1000. So ...it’s a maths game. I think...
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    Once-Weekly Semaglutide in Adults with Overweight or Obesity, 2021, Wilding et al

    I agree blinding does appear to be an issue, even small amounts of nausea etc will swing the results due to the power of suggestion. however it is also not clear how many people in the control group would have suffered side effects just from eating less compared to their normal eating regime...
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