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Check out Craig Robinson's maths catastrophe theory as applied to ME

A number of interesting comments now, including further contributions from @Jonathan Edwards .

thank you - from someone with 2 family members significantly affected this means a lot.

how any jenga bricks will it take?

Has degree been modelled - ie upstream and downstream effects of various levels of inhibition of various cell types susceptible to the "trap"; this is a systems condition - it is how this may affect other processes and mechanisms by degree that is the interesting bit. It never ceases to amaze...

The prose, as ever, is beautiful. The sense of loss is tangible. The oxymoron of happiness and grief a poignant reminder of how much this illness strips away. I'm so glad you have managed outside, it gives those in gilded bedroom cages hope. Thank you.

Magnesium is the one supplement that is instantly noticeable if we miss it. It is key to so many reactions. Lower core body temperature probably doesn't help either

Sorry to hear this @Sarah94 . We had a close relative who was entirely disbelieving until they watched Unrest. ( it is a good advocacy film for general public) That said they now feel awkward and don't engage much.

Future proofs your home - you are not the only one who may use it. Promotes independence and underpins potential for improvement for you - the avoidance of PEM may help you even out a activity and actually achieve more in the long run

Signed

this

Before I knew anything of this illness, and the politics engulfing it, I was annoyed that there were no specialists anywhere near us. Now i realise that we are in a better place than many others. ( and the current place is not too good) . I now have knowledge and my daughter understands her...

Thanks- I obviously didn't t read the paper.

I wonder what would have been found 3/ 4/ 7 days after.PEM may start on 2nd day but may be nowhere near its peak.

Autism presents differently in females and support services are only now getting to grips with this- very slowly. (similar to how females present differently with heart attacks etc - the whole gender ratio may be changing as more research becomes gender balanced) The male /female ratio may be...

Thread split from “Graded exercise therapy: Chronic fatigue syndrome” by The HANDI Working Group (2019) Who comprise the HANDI group and what are their interests. Interesting re timing of this piece

Ironic that the first item on the "most popular" links on the right hand side of the article page is Why a Gaslighting/Narcissist Relationship Is So Devastating?

Systems and maths and knowledge of ME - few and far between . off top of my head - Gordon Broderick who has worked with Klimas and Craig Robertson who works with Myhill ( his premise on mathematical catastrophe theory as applied to ME is kind of like a bistability switch)

thank you

Yes. When energy is low your body adapts to try and enable you to continue functioning. My daughter's s posture and gait changes when exhausted or in PEM.