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  1. Forbin

    Erythrocyte Deformability As a Potential Biomarker for Chronic Fatigue Syndrome, Davis et al (2018)

    It does seem like this would have been reported previously if it was visible on a routine test. Maybe this is something seen only after the cells exit a narrow channel like a capillary. If the cells are relatively inelastic, perhaps they retain their compressed shape longer after squeezing...
  2. Forbin

    Persistent fatigue induced by interferon-alpha: A novel, inflammation-based, proxy model of Chronic Fatigue Syndrome, 2018, Pariante et al

    It seems from the video of Professor Pariante's talk back in October that IL-6 and IL-10 were already a bit elevated in the patients who went on to develop persistent fatigue, even before they started taking interferon alpha. He draws attention to the fact the the levels of IL-6 and IL-10...
  3. Forbin

    Persistent fatigue induced by interferon-alpha: A novel, inflammation-based, proxy model of Chronic Fatigue Syndrome, 2018, Pariante et al

    It seems like these findings were foreshadowed by the results of the 2006 Dubbo study, which showed a connection between the apparent severity of the initial infection and the later development of ME. So, the worse/more fatigued you initially feel from the "trigger"/initiation of interferon...
  4. Forbin

    Hematological and psychophysiological correlates of anomalous information reception in mediums: A preliminary exploration, 2018, Beischel et al

    Jethro: "I read up here on these here castle ghosts, and all you gots to do is hold a séance and exorcise the rascals." Miss Jane: "But Jethro, you're not a medium!" Jethro (embarrassed): "I know. I'm a large."
  5. Forbin

    Suddenly feel completely well

    There was another thread where some people, myself included, talked about feeling better after waking up after only a few hours of sleep. I flew across county once and then slept only about 4 hours before I had to get up. When I woke up, I felt way better than usual. It lasted for 6-8 hours, but...
  6. Forbin

    Suddenly feel completely well

    It would seem like a good idea to get and store a blood sample from patients who suddenly feel well. These "well" samples could then be compared to either earlier blood samples taken while ill, or to future blood samples should they relapse. Comparing self-to-self seems like the ultimate...
  7. Forbin

    Parachute use to prevent death and major trauma when jumping from aircraft : randomized controlled trial

    This study is a thing of beauty - sort of like an elegant ocean liner - deploying a parachute - as it falls from the sky.
  8. Forbin

    Cases of Acute Flaccid Myelitis in Minnesota and other states

    It seems odd that AFM is peaking every other year (at least since 2014). When I searched for "biennial virus," the only two that seemed to show up were "Respiratory Syncytial Virus" and "Parainfluenza Virus," both of which are human respiratory viruses. It seems they think AFM may be caused...
  9. Forbin

    Is there a link between allergies and ME/CFS?

    Post onset, I had provocative skin testing done. I had some reactions to grasses, but, apparently, a fairly major reaction to corn. This seemed somewhat odd, since I never previously noticed any reaction from eating corn or products containing corn as an ingredient. Post onset, I did have a...
  10. Forbin

    Has anyone had any relief from vision issues. Laptop use currently hurting my brain!

    I think you're right and that your eyes are moving in anticipation of the screen scrolling. If you have dizziness/vestibular problems, trying to visually track objects can make you feel dizzy. When my dizziness was at its worst, I'd momentarily feel dizzy just from watching a car move across a...
  11. Forbin

    Increased risk of chronic fatigue syndrome following burn injuries, 2018, Tsai et al

    Sounds like they are talking about sunburn as opposed to heat injury. Although I used to get mild to moderate sunburns as a child, it stopped when I was a teenager and no longer had access to a pool. However, I went out on a friend's catamaran in my early twenties - one or two years before the...
  12. Forbin

    Livestream Alan Light, PhD today at 6pm MST "New findings suggest that multiple mitochondrial mutations create susceptibility for ME/CFS"

    I got "page not found" at the above link for the live stream, but this worked: https://www.facebook.com/batemanhornecenter/videos/331133540814821/UzpfSTY3NDU0ODk5MjY0OTg1MjoxODMyNzczNzIzNDk0MDM0/
  13. Forbin

    Erythrocyte Deformability As a Potential Biomarker for Chronic Fatigue Syndrome, Davis et al (2018)

    Interesting computer simulation of RBCs moving through a retina capillary. Gives a sense of the deformation that goes on. I suspect that this is slowed down compared to real time. You can set it to go 1.5x faster by clicking on the gearwheel next to "YouTube."
  14. Forbin

    Jeopardy (TV show) asks a question based on SEID/CFS

    "No, I'm afraid that now makes it all three contestants who answered 'What is The China Syndrome?'"
  15. Forbin

    Erythrocyte Deformability As a Potential Biomarker for Chronic Fatigue Syndrome, Davis et al (2018)

    FWIW, it seems that one way RBCs can become more rigid is when small molecules (ligands) bind to a protein in the cell membrane called glycophorin A (GPA), which, in turn, interacts with other proteins in the cell membrane, reducing deformability. When tracer antibodies to human glycophorin A...
  16. Forbin

    Erythrocyte Deformability As a Potential Biomarker for Chronic Fatigue Syndrome, Davis et al (2018)

    About eight months after onset, I underwent a battery of tests at a "famous" otologic institute to try to figure out the cause of my continuous "dizziness." They seemed stumped, but a senior doctor there said that they sometimes saw this kind of dizziness with "vascular insufficiency" to the...
  17. Forbin

    Stanford Community Symposium 2018: Phair, Metabolic traps, Tryptophan trap

    I stumbled upon this May 2018 article concerning Tryptophan, the Kynurenine Pathway and IBD (Inflammatory Bowel Disease). Tryptophan Metabolism through the Kynurenine Pathway is Associated with Endoscopic Inflammation in Ulcerative Colitis...
  18. Forbin

    News from the Institute of Neuroimmune Medicine (INIM), NOVA, Nancy Klimas

    Hopefully, this grant reflects on some success they've seen in their recent GWI trial. They're looking to do something similar in relation to ME, but are having trouble finding funding. In a video posted on this thread, Dr. Klimas said that a Parkinson's group had agreed fund a small ME/CFS...
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