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  1. Forbin

    Chronic fatigue syndrome in the emergency department (2019) Timbol and Baraniuk

    Feel free to start a thread on it, @DokaGirl!
  2. Forbin

    Chronic fatigue syndrome in the emergency department (2019) Timbol and Baraniuk

    Ironically, rather than being the attention seeking hypochondriacs they are sometime caricatured as, a real issue for ME/CFS patients is the degree to which their experience with the medical profession eventually makes them averse to contact with it. (It certainly has in my case.) It's all but...
  3. Forbin

    Charles Darwin’s ailments are ‘typical of Lyme disease’ in UK - The Guardian

    I'm not sure if you're looking for Shorter's paper "Chronic fatigue in historical perspective" from the May 1992 CIBA conference, but it can be seen here starting on page 6. The book was originally published in 1993, but this citation seems to say it was first published online in 2007. There's...
  4. Forbin

    Charles Darwin’s ailments are ‘typical of Lyme disease’ in UK - The Guardian

    The article I linked to above touches on the issue of class in the diagnosis of neurasthenia...
  5. Forbin

    Estimating Prevalence, Demographics and Costs of ME/CFS Using Large Scale Medical Claims Data and Machine Learning, 2018, Valdez, Proskauer et al

    I don't think it accounts for everything, but... Leonard Jason's figure of 422/100,000 (.422%) is only intended as an estimate of the adult US population with CFS. If this current study is not confined to adults, you'd expect it to come up with a somewhat larger number - though a doubling of...
  6. Forbin

    Charles Darwin’s ailments are ‘typical of Lyme disease’ in UK - The Guardian

    I would have thought so, just because the word conjures up images of 19th century tintypes of women splayed on fainting couches - but it turns out that it was mainly men who were diagnosed with neurasthenia, which was thought be a consequence of the fast-paced, energy-sapping qualities of...
  7. Forbin

    Charles Darwin’s ailments are ‘typical of Lyme disease’ in UK - The Guardian

    Strange. It's just seems to be the website of a small county newspaper in Montana. It's a 2011 article by a local doctor about how peptic ulcers are now treatable with antibiotics.
  8. Forbin

    Charles Darwin’s ailments are ‘typical of Lyme disease’ in UK - The Guardian

    According to this article: Of course, there was a time when peptic ulcers were considered a self-reinforcing product of "emotional stress." That time has passed. Has anyone alerted Sir Simon, I wonder?
  9. Forbin

    Pulsatile Tinnitus

    I've definitely experienced this at times. For me, it's more or less of a "whooshing" sound that might suggest turbulent blood flow. Some believe that it is caused by high blood pressure in the carotid arteries, perhaps due to plaque buildup there - but I've heard this kind of thing...
  10. Forbin

    United Kingdom: Science Media Centre (including Fiona Fox)

    In Oscar Wilde's "The Picture of Dorian Gray," Lord Wotton says that he likes to choose his enemies for their good intellects. Unfortunately, even in this regard, it looks like ME patients are once again screwed.
  11. Forbin

    Signs of Hypoxia - anyone had this?

    I wonder if you would see signs of hypoxia, like blue lips and fingernail beds, if the blood simply couldn't be delivered in an adequate amount to the smallest vessels - perhaps as a consequence of reduced blood cell deformability, or maybe as an effect of some impairment of nitric oxide's...
  12. Forbin

    Top 10 scientific publications in ME/CFS over the last 10 years based on number of citations [Tweet by Dr Mark Gutheridge]

    Maybe the lower number of citations attributed to biological research is just an indication of the relative difficulty of conducting and publishing such research. Biological research often requires carrying out hundreds, if not thousands, of complex and sensitive experiments that involve...
  13. Forbin

    Erythrocyte Deformability As a Potential Biomarker for Chronic Fatigue Syndrome, Davis et al (2018)

    Thanks! For some reason, I thought the original article was an "abstract" and that the full paper was either behind a paywall or had been embargoed all this time. As you pointed out, the original article looks like it appeared in the "proceedings" of a blood conference. I wonder if this was an...
  14. Forbin

    Erythrocyte Deformability As a Potential Biomarker for Chronic Fatigue Syndrome, Davis et al (2018)

    Any idea why this has a different title, is in a different journal and has one less author than before? The text is also different, though it covers the same ground. Was the original merely an "article," while this is the "paper?"
  15. Forbin

    Signs of Hypoxia - anyone had this?

    A couple of years after onset, I had a couple of doctors (gastroenterologists at UCLA) take note of the color of my fingernail beds and ponder their significance. I think my nail beds are somewhat darker and more deeply colored than usual (and perhaps slightly tinged blue). To me, it seems...
  16. Forbin

    David Tuller: Trial By Error: “Talk is Cheap,” Patients Tell NIH

    My impression is that, if we want to get significantly greater funding in the U.S. than we currently have, then the most effective way to get it is through the political means of lobbying the U.S. Congress. Francis Collins clearly has influence over some discretionary funding - and I appreciate...
  17. Forbin

    Two age peaks in the incidence of chronic fatigue syndrome/myalgic encephalomyelitis: a population-based registry study from Norway…, 2014, Bakken+

    Maybe the peaks represent the time when you're most likely to be exposed to some virus that provokes a strong immune response. The early peak might represent when you're in school, while the later one represents when your children are bringing home viruses from school. [The early peak around...
  18. Forbin

    Persistent fatigue induced by interferon-alpha: A novel, inflammation-based, proxy model of Chronic Fatigue Syndrome, 2018, Pariante et al

    FWIW, in the late 1980's I saw a PBS documentary about initial attempts to use interferon as an experimental treatment for cancer. Not long after the infusion, the patient experienced an episode of prolonged, uncontrollable shaking, like you'd get if you were severely cold. It's called "rigor"...
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