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This may get outsized attention, not just because it's in the New York Times, but also because the lead author is from Emory University, which is literally across the street from the CDC. As I recall, the CDC's Dr. Reeves collaborated with Emory University's Department of Psychiatry and...

Forgive me if I missed it, but I don't recall "emotional distress" being a "recognized trigger" of ME/CFS. Possibly, it's a reference to the next line: That "link" has always seemed extremely dubious to me and, even if it were somehow true in some cases, it would be an antecedent, not a trigger.

This study, by Drs. Alan and Kathleen Light, showed significant increases in the expression of certain sensory, adrenergic and immune genes over time in CFS patients vs control following moderate exercise. The top line shows the controls. The CFS patient response is at the bottom. Alan Light...

If a lot of ME patients do have abnormal sleep patterns (I certainly do), I wonder how that might have affected all those studies on "morning cortisol" that they used to love to do on ME patients. It's probably not very sensible to test the "morning cortisol' level of people who would normally...

It's really quite simple - DGBI are the same as FGIDS. :) Technically, neither is an acronym since, by definition, acronyms can be pronounced (like "NASA"). DGBI and FGIDS are just confusing and redundant initialisms - especially since both are plural.

Could be worse... could be "Yuppie Covid."

I think, for some people, ME takes a while to evolve. On my doctor's recommendation, I tried to exercise my way back to health on a stationary bike just a couple of months after onset. I desperately wanted to get better, so I really tried hard for more than a month [It didn't help at all]. I...

Leonard Jason's 1999 prevalence figure for US adults 18 and over was 0.422% The current US Population over 18 (2019 estimate) is 255,042,109 255,042,109 x 0.00422 = 1,076,277 current US cases over 18 meeting Jason's criteria. This assumes the prevalence has remained steady since 1999, when...

Coincidentally, I'm going to get the flu vaccine at the local pharmacy this evening. I started to get annual flu shots after I came down with what was probably the "Swine Flu" (H1N1/09) in June 2010. In the US, the epidemic lasted from the spring of 2009 to August 2010, so I was "lucky" enough...

If you're worried that you may have missed it, it looks like "Triple Giving Tuesday" runs from today (10/20) through December 1st ( a total of 44 days, I think). https://www.omf.ngo/2020/10/15/triplegivingtuesday-is-almost-here/

I'd be interested in a prospective study that tries to capture data on patients as the severity of their symptoms undergoes long term shifts. Anecdotally, it seems like some patients experience a level of improvement (though not necessarily recovery) during a window of 3 to 5 years after onset...

So, I believe when you boil this concept down to its essence you get... Thanks.

True spinning vertigo is the worst. I don't know how it's possible to function at all with that. I think the general term "balance problems" or "balance impairment" should probably be used in lists of ME symptoms. The more specific terms are easily confused with one and other. My concern is...

I always look for "dizziness" in lists of ME symptoms. It seems like it shows up maybe 50% of time. Perhaps that's how often it shows up in patients. I wish it showed up in lists more often. People just can't grasp how incapacitating it can be when it's chronic. "Lightheadedness" tends to sound...

That would be an interesting relationship. FWIW, a genetic form of long QT syndrome may be rare, but acquired/transient long QT syndrome may be more common. The acquired form can result from certain drugs, including certain classes of antibiotics. Also, low potassium and/or magnesium...

I bet this is pretty much the same level of consternation that the priestly class felt not long after the printing press was invented in the middle of the 15th century.

I wonder what factors determine the size distribution of EVs, and if any other conditions show a distribution like the one they found. I did find this overview of EVs, but it seems a bit "above my pay grade" on first glance. Overview of Extracellular Vesicles, Their Origin, Composition...

So blood pressure and heart rate did not change between being supine and sitting in either group, but the initial blood pressure was higher in the ME/CFS group (though not significantly so). Is the implication that low blood volume in ME/CFS patients is behind the decreased cerebral blood flow...

True. I suppose, though, that you might say that "CFS" is about 40 years old, because that nomenclature evolved out of U.S. outbreaks from the very early 80's that were originally thought to be EBV. The original article published in 1984, "Chronic Mononucleosis Syndrome" (in the Southern...

So far as I know, King became interested in ME because his friend and colleague, retired Wall Street analyst Deborah Waroff, has been afflicted by it since 1989. Together they created a YouTube series called "ME/CFS ALERT" which is devoted to investigating the disease from many different angles.