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Not necessarily. It could have been there all along, but in a dormant or sub-clinical state, and was then kicked into high gear by some trigger.

ME symptoms masking the early non-specific symptoms of other diseases concerns me.

“It was almost like it’s set up for people to fail” And/or to avoid accountability if it does fail people.

It isn't like a substantial prodromal phase is an unknown thing. Cancers, for example, don't spring up overnight, fully formed and making their presence felt.

Once people finish coming to Fraser’s clinic they often don’t respond to follow-up queries, so it is hard to know exactly how fully they have recovered Or even if they partially 'recovered' in the first place, in any meaningful sense.

And would somehow spin that into anti-psych prejudice.

TLDR: No benefit was found.

he he

Mostly by shifting responsibility to the patient, and the blame when it inevitably goes wrong. It is just an excuse generating mechanism for the inevitable limits to doctors' knowledge, coupled with their cowardice in refusing to stand up against the endless cost cutting to the health service.

Goal shifting and gaslighting, par excellence.

Ugh, I just can't be bothered with these idiots anymore. They are selling a book. Enough said.

Might be suffering from PFS. Perpetual Fad Syndrome.

Nobody is rejecting n=1 anecdotal evidence out of hand. What is being rejected is that such evidence is a sufficient basis for recommending any treatment to other patients, without robust clinical trials. Particularly from the safety angle. There is no short cut to good evidence, and effective...

For some patients, at least. Not suggesting it happens to all patients.

I don't think they intend harm, as such, just that it takes a distant second place to their self-interest. One of the most powerful of all. Agreed.

Seems clear to me that simply disappearing the whole ME diagnosis by replacing with a 'functional' diagnosis is now their primary means to avoid accountability and reform, and keep their empires intact. It just proves – as if any more proof were required – that they are utterly shameless and...

If you prefer a lower dose then it usually easy enough to cut tablets in half. Buy some empty gel capsules (enteric coated, white ones), and put half a tablet in one of them. I have done that before when the correct dose tablet was temporarily unavailable.

Could also be a stable sub-clinical state, which then gets flipped more or less overnight into a much more serious state by a short term infection, for example. –––––––––– "An increasing number of sexual assaults (SAs) are being reported." Which is a different metric from an increase in...

Trimipramine is no longer available in Australia. Was removed from the approved list last month. https://www.healthdirect.gov.au/medicines/brand/amt,35939011000036105/surmontil

I think this is one of the biggest technical questions about ME: Is there a prodromal phase, where the disease process is in place and actively affecting patients' lives, but is still at the relatively mild end of the spectrum, and the symptom expression is not yet sufficiently distinct to allow...