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Excluding the BBS, there were statistically significant improvements in all outcomes between weeks 1 and 8 and between weeks 1 and 3-month follow-up. Did any of them reach clinical significance?

Okay, he gets a little wriggle room, for now. I still bitterly resent being used as cannon fodder for other people's crusades.

Does he make equally sneering jokes about psychs and their claims and behaviour? When he starts kicking up just as hard, I will start giving him a little more wriggle room.

Effect sizes matter.

Ricky Gervais' behaviour/attitude is the epitome of the kind of bully boy privilege that excess of success and lack of experience of real suffering and injustice brings forth. You are not a daring edgy comedian confronting the world with some hard truths, Ricky. You are just an entitled...

Which, according to them, is every single disease, current and future. It is little more than a massive blatant power grab.

Well said.

Par excellence. They are just throwing everything and anything they can think of against the wall, hoping something, anything, will stick.

Yep. It is why they have to keep coming up with new labels, and endlessly repeat claims about them being new insights and understandings. It is the same crap as when I first started learning about the science of ME/CFS (or lack of it) over 35 years ago. It is now understood that FNDs’...

We identified distinct cortical areas showing a progressive increase in cortical thickness across different groups, Dose-response relationships are usually good evidence.

Almost infinitely flexible. The concept of an organic problem being variable, and the patient being able to at least partially or temporarily override it or compensate for it, has apparently has completely escaped these people. I have mild standard age-related osteoarthritis in my hands and...

I have sometimes wondered how different the ME story could have been if the gender balance was inverted.

Yay team! :balloons::party:

This is the bit I really struggle to make sense of. There is no way Cochrane can come out of accepting lower methodological and ethical standards looking good. I find it difficult to believe that at least some of the senior members there do not grasp this. What is their end game here? Or have...

This. Replicating in this context means identifying, isolating, and maximising known biases and confounders, and then redefining them as therapeutic benefits. Which is not science. It the complete opposite: anti-science.

A significant obstacle in securing medical acknowledgement of fatigue is the lack of comprehensive and accurate biomarkers. A significant obstacle in securing medical acknowledgement of fatigue is the lack of funding for a comprehensive research program for accurate biomarkers.

The difference in outcomes are largely indistinguishable for the patient. At some point the persistent failure becomes wilful, they start choosing to not see the problem(s). We are at the stage where anybody claiming to be a qualified professional in this area cannot plead ignorance of the...

Queensland health are the worst on this in Australia (far as I know). Somebody with high level influence in that state government is a BPS fanatic. They are not even original. Predisposing, precipitating, and perpetuating. Straight from the psych playbook on ME.

Pain is also a common symptom in CFS, and fatigue in FM. A bit too arbitrary a distinction for my taste.

Their track record of bad faith, especially post-NICE & with Cochrane, is too persistent and stark and damaging for me to give them any more benefit of the doubt. They have made it abundantly clear that they think they own us, and nobody, least of all us, have any right to say otherwise. Far...