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  1. Mij

    Review Systematic review and meta-analysis of the prevalence of chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME), Eun-Jin Lim et al, Feb 2020

    Merged Dear Editor, We have read Lim et al.’s study [1] with great interest. Studies of this illness are scarce, so their article is important in establishing the global prevalence systematically. In fact, it has been cited over 200 times and has had a significant influence on global reporting...
  2. Mij

    Review Dysregulation of lipid metabolism, energy production, and oxidative stress in [ME/CFS], [GWS], and Fibromyalgia, 2025, Davis, Morten et al

    I had 'high' oxidative stress biomarkers during sampling. I also had poor plasma values for all antioxidants.
  3. Mij

    Renegade Research

    April 11, '25: "Orthostatic Flow Syndromes" Clinician's Roundtable zoom by Interventional Radiologist Steve Smith, MD. Relevant for POTS, fibromyalgia, ME/CFS, migraine, brain fog, IBS, vulvodynia, ADHD, and more. Register: LINK
  4. Mij

    PEM discussion thread - post-exertional malaise

    I was only able to figure it out when my symptoms stabilized through trial and error. It took YEARS to figure out though.
  5. Mij

    PEM discussion thread - post-exertional malaise

    I don't know how to answer this but I experienced this for 11 years after onset during the time period. I didn't have symptoms of delayed PEM. As long as I got adequate rest for 2-3 days in between activities I was ok and back to my 'normal'. I was able to control my activities because I...
  6. Mij

    Exploring the Molecular Pathways of Long COVID With Post-Exertional Fatigue: A Multiomic Approach, 2025, Chafino-Aixa et al

    Abstract Body Background Post-exertional malaise (PEM) is a disabling condition characterized by worsened symptoms after mental or physical exertion, commonly seen in Long-COVID (LC). While its underlying pathophysiology is unclear, potential mechanisms include oxidative stress, and metabolic...
  7. Mij

    PEM discussion thread - post-exertional malaise

    Hopefully we can move away from the term ME when they figure out the pathophysiology of delayed PEM.
  8. Mij

    Trial Report Blood Flow To The Head Is Reduced in a Patient With Myalgic Encephalomyelitis With Confirmed Post-Exertional Malaise, 2024, Lee

    Meet Lumia Clip, a whole new way to wear Lumia. Our easy new adapter allows an alternate ear position for the Lumia Health wearable. Lumia tracks changes in blood flow to the head for people w/ orthostatic intolerance from chronic illness Pots, dysautonomia, LC, pwME
  9. Mij

    PEM discussion thread - post-exertional malaise

    I was diagnosed with "atypical ME" 32 years ago by an ME expert. He did not think I had ME from his 25 years of experience. I had what was described as PVFS for several years. I didn't experience delayed PEM for years after onset, even after exercising, my leg muscles just felt...
  10. Mij

    PEM discussion thread - post-exertional malaise

    To add to the mix is that some of us don't experience many or noticeable ME/CFS symptoms, and delayed PEM feels like a whole different illness. When I didn't have OI or cognitive issues for 11 years after onset and was feeling 90% improved, I still experienced the same horrible delayed PEM...
  11. Mij

    Pharmacokinetics and safety of one-yearly lenacapavir; a phase 1, open-label study, 2025, Vamshi Jogiraju, PhD et al

    Summary Background Long-acting antiretrovirals can address barriers to HIV pre-exposure prophylaxis (PrEP), such as stigma and adherence. In two phase 3 trials, twice-yearly subcutaneous lenacapavir was safe and highly efficacious for PrEP in diverse populations. Furthering long-acting PrEP...
  12. Mij

    Antibody reactivity against EBNA1 and GlialCAM differentiates MS patients from healthy controls, 2025,Neda Sattarnezhad et al

    Significance Multiple sclerosis (MS) is an autoimmune disease of the brain and spinal cord, leading to disability in young adults. Infection with Epstein–Barr virus (EBV) is a prerequisite for developing the disease. We previously demonstrated that antibody responses against the virus protein...
  13. Mij

    Shingles vaccines, chickenpox, Shingrix

    So the doctor and pharmacist aren't sure exactly when to get vaccinated with Shingrix after infection but if you still have symptoms it's best to wait one year because of side effects from the vaxx. The Rx was sent in so I will wait one year :emoji_fingers_crossed:
  14. Mij

    The medical term "Clinophilia": "liking to lie down"

    In the context of autism, the medical term for sound sensitivity is hyeracusis. It's also sometimes referred to as auditory hypersensitivity or decreased sound tolerance. I'm not autistic but I do read many posts on social media that describe what I experience, including sensory overload...
  15. Mij

    Impacts of the 2024 change in US government on ME/CFS and Long Covid

    The removal of "women and underrepresented" isn't woke, it is a fact that women are underrepresented in research.
  16. Mij

    The medical term "Clinophilia": "liking to lie down"

    Is there a medical term for the need to wear earplugs?
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