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  1. Mij

    Identifying and renaming inaccurate, inappropriate or minimising words, phrases, etc. in ME/CFS

    The ME doctor I saw in the early 90's never used any term. Physicians should simply tell patients not to exercise.
  2. Mij

    Impacts of the 2024 change in US government on ME/CFS and Long Covid

    October, 2024 to March, 2025, Ontario has reported a total of 572 measles. The number of cases reported in Ontario over the last week is more than the number of cases recorded over the course of a decade between 2013 and 2023.:jawdrop: Mostly unvaccinated children.
  3. Mij

    Open Medicine Foundation (OMF)

    Full Article: Targeted analysis of seven selected tryptophan-melatonin metabolites: Simultaneous quantification of plasma analytes using fast and sensitive UHPLC-MS/MS Abstract Tryptophan-derived metabolites, a group of neurotransmitters essential for various brain functions, play key roles...
  4. Mij

    Open Medicine Foundation (OMF)

    New Publication: Targeted Analysis of Seven Selected Tryptophan-Melatonin Metabolites The ME/CFS Collaborative Center at Uppsala published a paper on their new methodology: ultra-high performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS), which can separate and quantify...
  5. Mij

    Melatonin attenuates spinal cord injury by regulating ferroptosis through the Nrf2/HO-1/GPX4 pathway, 2025, Zhengxi Yu et al

    Abstract Spinal cord injury (SCI) is one of the most devastating and catastrophic types of injury, with high rates of mortality and disability. Ferroptosis has become the target of many major incurable human diseases. By inhibiting ferroptosis, melatonin (MT) can reduce the damage in various...
  6. Mij

    Canada - Unknown brain disease in New Brunswick

    Analysis of 'undiagnosed neurological illness' underway, too soon to talk possible source, says doctor "The New Brunswick government has begun the "data analysis phase" of its investigation into undiagnosed neurological symptoms affecting hundreds of people in seven provinces and whether...
  7. Mij

    News from Canada

    Trump threats open 'floodgate' of inquires from U.S physicians about moving north "Some Canadian doctors are also turning down opportunities in the U.S" "Renowned Ottawa heart surgeon Marc Ruel was planning a move to the United States last year, with the University of California, San Francisco...
  8. Mij

    News from the USA, United States of America

    NEWS 27 March 2025 75% of US scientists who answered Nature poll consider leaving "Cuts to research funding in the US have forced many scientists to rethink their careers" "More than 1,600 readers answered our poll; many said they were looking for jobs in Europe and Canada"
  9. Mij

    Iron dysregulation and inflammatory stress erythropoiesis associates with long-term outcome of COVID-19, 2024, Hanson et al

    Have you had your ceruloplasmin levels tested? Mine was below ref range when my ferritin kept dropping for 25 years. Role in Iron Metabolism: Ceruloplasmin plays a role in iron metabolism, specifically in the release of iron from cells and its transport in the blood. Iron Transfer...
  10. Mij

    Iron dysregulation and inflammatory stress erythropoiesis associates with long-term outcome of COVID-19, 2024, Hanson et al

    @Sean am I reading this correctly that SiderAL Forte has 30,000mg of iron (214%) per capsule??
  11. Mij

    Stories of mis-diagnoses in the media

    Merged thread UK: Article in the Metro: I told the doctor my symptoms, then I saw an eye roll Finally I had the diagnosis I’d been searching for, for 19 years More at link.
  12. Mij

    News from the USA, United States of America

    Long Covid office 'will be closing', Trump administration announces The move comes as part of the administration’s reorganization of HHS, according to an internal email seen by POLITICO. The Trump administration is shuttering HHS’ long Covid office as part of its reorganization, according to...
  13. Mij

    COVID-19 brought about a large rise in blood circulation disorder cases, study suggests

    Scientists and physicians have long believed postural orthostatic tachycardia syndrome, commonly known as POTS, could be brought on by viral infections. The Epstein-Barr virus in particular has been posited as a possible trigger for the syndrome, which is characterized by an inability to...
  14. Mij

    In-cell architecture of the mitochondrial respiratory chain, 2025, Florent Waltz et al

    AI overview: Yes, cryo-electron tomography (cryo-ET) can be used to study the changes in cellular signaling pathways that occur after exercise, allowing researchers to visualize the localization of signaling molecules and the activation of signaling pathways in a near-native cellular...
  15. Mij

    Covid-19 vaccines and vaccinations

    Belgium, Austria, and Switzerland researchers review shows age weakens immune responses but not uniformly. Adjuvants and mRNA vaccines improve vaccine effectiveness in older adults, with adjuvants showing the most consistent success. Age-related changes in the immune system and challenges for...
  16. Mij

    In-cell architecture of the mitochondrial respiratory chain, 2025, Florent Waltz et al

    The cell's powerhouses: Molecular machines enable efficient energy production Perspectives into evolution and health In the future, the researchers aim to uncover why respiratory complexes are interconnected and how this synergy enhances the efficiency of cellular respiration and energy...
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