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  1. spinoza577

    A nanoelectronics-blood-based diagnostic biomarker for ME/CFS (2019) Esfandyarpour, Davis et al

    And this is rather a very good sign, I think. I think this happens often, that you don´t come up with a plan which then leads to a discovery, but you are aware of possibilities and even odd possibilities, and then by accident something almost stupid looking succeeds. This actually may be the...
  2. spinoza577

    The experience of fatigue in neurological patients with Multiple Sclerosis: a thematic synthesis, 2020, Newton et al

    May I ask you, if wouldn´t be too complicate, could you elaborate? I ask this because I am pretty interested in this issue. I don´t see a logical point to be able to successfully differentiate between these two, so it remains that it must be an empirical difference. I guess supramaximal twitch...
  3. spinoza577

    Patient's experiences and effects of non-pharmacological treatment for ME/CFS - a scoping mixed method review - 2020 - Mengshoel et al

    A sequence that especially shows unwillingness: It´s almost magic, also that unknowns and knowns are muddled up by ... Which facts? Did anybody show any psychological property that PwME had in common? Any history, any kind of expectation, any whatever? Or do we explain illnesses now with...
  4. spinoza577

    Coronavirus - worldwide spread and control

    In Germany (in most areas) on April 20th most shops have been allowed to reopen, a bit later it was all of them. On April 27th masks have become mandatory in shops and busses asf. It does not seem that the relaxations have had any significant negative impact. daily detected cases daily...
  5. spinoza577

    A nanoelectronics-blood-based diagnostic biomarker for ME/CFS (2019) Esfandyarpour, Davis et al

    There are also almost no paragraphs (generally a bad sign, as I think). There is a paper on potassium currents in nerve cells of some brain areas. It says that nitric oxides changes the dynamics of voltage gated potassium channels, bringing more potassium out of the cell, thereby allowing the...
  6. spinoza577

    Twitter debate: controversies in functional gastrointestinal disorders, 2020, Maurice

    As opposed to the easy area of functional neurological disorders.
  7. spinoza577

    My comments to the Cochrane review

    Yes, this no hindsight knowledge, but intrinsically a matter of debate, which they completely failed to spot.
  8. spinoza577

    My comments to the Cochrane review

    My paragraphs here: An important point. In this view, the PACE study was rather a trial to show indirectly that the deconditioning theory is true: A successful treatment, made upon this assumption, would indicate that the assumption could be true. "Could be" rather, similar to a wet street that...
  9. spinoza577

    Coronavirus - worldwide spread and control

    If I am allowed to stress what I find especially important in @mango ´s quote, it´s this: I think the biggest problem is that there (still, of course) is uncertainty, and it seems to me that decision makers have problems to deal with it in a focusing way. I think also researchers have...
  10. spinoza577

    Plasma Neuropeptide Y: a biomarker for symptom severity in chronic fatigue syndrome, 2010, Fletcher et al

    My constant impression from my own experience and from forums is that there are not such negative thoughts, and that there is no depression. It might be not representative, but also this nice ME video #23 from a few days ago doesn´t indicate any depression or negative thoughts in these PwME. I...
  11. spinoza577

    Coronavirus - worldwide spread and control

    But a threshold is defined as the minimum strength you need to excert the effect. This minimum strength is therefore part of all other strengths that can excert the effect. Below a threshold there is no effect. Or there is no threshold at all. This would mean that "as few as" answers to the...
  12. spinoza577

    Coronavirus - worldwide spread and control

    For flu there is precaution as well, in fact in 2018 the vaccine didn´t work well (so have heard). Nevertheless you would not come up to stop normal life (or is this changing now?). Secondly, you need to show that the measures have an effect, this is not clear by itself. I said it already...
  13. spinoza577

    Coronavirus - worldwide spread and control

    In first instance I agree, but I principally disagree for an assessment of the whole situation, and insist to take possibilities into account. If we would like to know how dangerous the virus is, we are in this knowledge not interested in how dangerous our inability to cope with a difficult...
  14. spinoza577

    Coronavirus - worldwide spread and control

    True, such an assumption is simplifying, saying that excess rates 2018 are due to flu and 2020 due to covid-19. This objective accounts for both viruses and years. But do you have an alternative to figure out what goes on in a certain time period, say to investigate how sever a flu season was...
  15. spinoza577

    Coronavirus - worldwide spread and control

    Yes, and so far. He says that the virus seems to behave like other respiratory viruses, influenza and other corona viruses. Apart from being cautious, it´s not he who has to prove that this is the case, but it´s you who has to prove that this virus behaves in another manner. You have also to...
  16. spinoza577

    Coronavirus - worldwide spread and control

    I just got a very fine link, so that I thought I should share it, a pretty well done video comment on mortalities as shown by euromomo. Not what one may think anyway. "NOT What You May Think! Viral Mortality Comparison Between 2018 and 2020"
  17. spinoza577

    Coronavirus - worldwide spread and control

    What to me sticks out as well is that the graph doesn´t change after any of the easings. I guess this possibility should be taken into visible account, for clarity and further ideas. I still ask though, what the impact and effect of measures is at all. As in the three R´s I had given above can...
  18. spinoza577

    Coronavirus - worldwide spread and control

    As reality without perception is not knowledgable, so far some observations from euromomo in participating countries: The upper half of the site shows absolute deaths, The lower half excess deaths (which may so far be comparable in numbers to 2018). Countries can be seen separately as well...
  19. spinoza577

    Coronavirus - worldwide spread and control

    Here in Germany it was a professional who began to promote R0 as a relevant indicator, interestingly without explaining anything, just conveying something. Interesting also that it was the director of the CDC. Even more interesting only then, that he is a vet. The original strategy was to...
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