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I don't know this area well enough to back this up and it's possible I misunderstood. I recall her saying that most she gets coming through have scans for laying down but should be standing to see the gastroptosis. She seemed very sceptical of a gastroparesis diagnosis alone. Has anyone here...

Oh I just mean that we haven't shown that we can make individual cells experience PEM. It might be possible but it has not been shown. All we really know of PEM is clinical research of the patient function. We have some data that we will submit to publication in next couple months, not sure...

We've observed a push towards amino acids being used for ATP in a few studies (us and collaborators) and others have shown the same, anyone that has bothered to look has found the same. Typically sugar or fat is used for ATP production. This elevated use of amino acids in ME patients is...

Yes exactly. This is why it's been such a dominant type of research in the field. We still do this type of research. Have explored a diagnostic in the past (am even doing it currently) and it's incredibly hard to get up but not impossible. If you don't know that the marker is tied to the disease...

Yes it could. Actually there's a gastroenterologist in Queensland that thinks gastroparesis is getting misdiagnosed in people that have POTS group, she has seen many of these patients and finds they actually have gastroptosis. Something that can only be seen if you have a standing up X ray of...

Copied post and subsequent ones moved Yes it could. Actually there's a gastroenterologist in Queensland that thinks gastroparesis is getting misdiagnosed in people that have POTS group, she has seen many of these patients and finds they actually have gastroptosis. Something that can only be...

It's an interesting question to ask, are all cells operating under the same altered condition? Is it just a tissue specific phenomenon? Is it 1 in every 100 cells of a tissue that drag the rest down? Happy to answer any questions on this hypothesis or the nitrogen hypothesis.

I think generally we see that 99% of studies are looking to compare ME/CFS and healthy patients to find a marker that is distinctly different in 90%+ ME/CFS patients as compared to the healthy controls. And this is a tempting route to go down. The idea is that this whole research field is held...

That's interesting and not the first time I've heard that. I think reduced production of ATP per second (per second should be emphasised) is underlying fatigue and brain fog (a combination of vascular and central carbon metabolism issues varying between patients). There are a number of studies...

Hi Binkie, Chris Armstrong here. We were prompted to assess saline after receiving information from a lot of patients about treatments that were effective, also heard from a lot of clinicians. I've personally wanted to assess saline for a long time because I noted a lot of treatments that...