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Use of EEfRT in the NIH study: Deep phenotyping of PI-ME/CFS, 2024, Walitt et al
Interesting, yeah I could see why they might justify that to themselves as being enough of an outlier to exclude them (even if I don't think its a legitimate justification given all the other factors). But this is also why it's important to specify a priori what criteria will be used to...- andrewkq
- Post #104
- Forum: ME/CFS research
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Use of EEfRT in the NIH study: Deep phenotyping of PI-ME/CFS, 2024, Walitt et al
From what I can tell they only performed the GEEs using the binary ME vs Control variable in place of the anhedonia scales that Treadway used. They were essentially equating ME with anhedonia in the analysis to answer the question "Behaviorally, is ME just anhedonia?" Of course they don't frame...- andrewkq
- Post #103
- Forum: ME/CFS research
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Use of EEfRT in the NIH study: Deep phenotyping of PI-ME/CFS, 2024, Walitt et al
I agree that HV F's data suggests that they were not performing the task in the way that it was meant to be performed but I don't think that is justification alone for removing them. If the study team came back and said "There was clear evidence of equipment failure during HV F's task. The...- andrewkq
- Post #101
- Forum: ME/CFS research
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Use of EEfRT in the NIH study: Deep phenotyping of PI-ME/CFS, 2024, Walitt et al
Answer to #2: I reran the GEE models and when you include participant HV F (who was excluded for having "invalid data") the effect is no longer significant (p-value goes from .04 to .14). HV F just so happens to be the participant in the control group with the lowest PHTC value (aka the lowest...- andrewkq
- Post #93
- Forum: ME/CFS research