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Maybe subtle immune complement deficiencies are widespread Are problems fighting bacteria in early life an indicator along with allergies(hay fever) Is it those with subtle complement deficiencies that get worse COVID and does that include long COVID I saw a trial using Eculizumab for severe...

https://www.hindawi.com/journals/aurt/2012/868576/ High Complement Factor I Activity in the Plasma of Children with Autism Spectrum Disorders

https://panelapp.genomicsengland.co.uk/panels/111/ This is a research gene panel, currently in progress, to list genes associated with susceptibility to viral infection, covering SARS-CoV-2 and susceptibility to other viral infections

Aka Luvox,they titrate up to max dose then discontinue I found Luvox the easiest to tolerate and discontinue from

I think I may have Partial compliment factor I deficiency at 4q25 Trying to understand what aHUS is https://en.m.wikipedia.org/wiki/Complement_factor_I Factor I Inactivator of C3b/C4b It seems to be an area connected to macular degeneration and the eye

https://www.thailandmedical.news/news/covid-19-latest-study-identifies-factor-d-inhibitor-ach-145951-that-can-inhibit-direct-activation-of-the-alternative-complement-pathway-by-sars-cov-2- Factor D inhibitor and COVID

https://www.intechopen.com/books/a-comprehensive-review-of-urticaria-and-angioedema/pathophysiology-of-bradykinin-mediated-angioedema-the-role-of-the-complement-system Looking through the paper above I discovered I may have a partial complement deficiency factor (I) at 4q25 (A minor immune...

Could viral effect on the kidney and liver effect ability to detox ammonia causing brain fog

Does this study tie in with the one by fane mensah https://www.frontiersin.org/articles/10.3389/fimmu.2018.02421/full

Sleep inversion may be a symptom of elevated blood ammonia levels[2] and is often an early symptom of hepatic encephalopathy.[3] Sleep inversion is a feature of African trypanosomiasis after which the disease takes its common name "African sleeping sickness";[4] sleep-wake cycle disturbances are...

I think my target gene slc13a3 is linked to the kidney https://jagwire.augusta.edu/nci-grant-explores-potential-of-likely-tumor-suppressor-gene-in-kidney-cancer/ NCI-grant explores potential of likely tumor-suppressor gene in kidney cancer Glutathione is mentioned

https://www.verywellhealth.com/what-is-glutamate-715862 CFS & FIBROMYALGIA What is Glutamate?

SLC6A20 https://www.technologynetworks.com/genomics/news/study-finds-two-genetic-variants-associated-with-covid-19-susceptibility-336361 Are the SLC gene family the common factor for post viral fatigue states

Along the lines of auto brewery syndrome I wonder if there are other ones to be discovered like auto PCP syndrome ect

I was wondering if I can sneak back into the system by calling myself a long haul EBV

https://news.stanford.edu/2020/07/21/researchers-develop-portable-ammonia-detector/ Stanford researchers develop a portable blood ammonia detector I wonder how much it costs and is there anything else like it on the market

https://grantome.com/grant/NIH/R01-DK082528-01S1 Regulation of Energy Metabolism by PDP1 and PDP2

I worked out that theoretically my NAGS gene will be underactive along with a gene for pyruvate Maybe low pyruvate makes it harder to detox ammonia

Genetically I have a distant connection to NAGS deficiency I’m hoping it maybe partial NAGS with treatment but it maybe a long shot It’s treatment is carglumic acid and it’s expensive I hadn’t heard of Late onset urea cycle disorders until recently They can be connected to rare genetic...

I ended up at the liver potentially being my central cause as well,specifically under active enzyme of the urea cycle possibly resulting in (minimal?)ammonia passing through to detox in the brain and or muscle