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FoxO1, the transcriptional chief of staff of energy metabolism. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3228887/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1642148/ Epstein-Barr Virus Represses the FoxO1 Transcription Factor through Latent Membrane Protein 1 and Latent Membrane Protein 2A▿

Is there a high rate of cell destruction and turnover in mecfs,apoptosis I think it’s called

https://en.m.wikipedia.org/wiki/Methanethiol Maybe I’m smelling mercaptan then as it says it’s produced by the body

Natural Gas and Mercaptan . This additive is called Mercaptan (Methanethiol: CH 3 SH). Mercaptan occurs naturally in marshes, natural gas in some areas, and in some crude oils. Mercaptan is highly flammable and at very high concentrations it is highly toxic and affects the central nervous system.

I get this it smells methane like

https://en.m.wikipedia.org/wiki/PI3K/AKT/mTOR_pathway I have a low platelet count.

Is there a link

I think it’s important to understand anti psychiatry and critical psychiatry’s viewpoint to understand how they had influence over M.E The no hard evidence,no illness idea. In some ways Anti psychiatry is kind,but in other ways cruel,I still cannot decide if it’s origins and intentions are...

Are the areas of the brain mentioned in the video the same as suspected areas for mecfs

EBV still seems to be of high interest to the MS St Barts blog A basic fact I never see mentioned is EBV surpresses FOXO1 And I think that’s important https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1642148/ FOXO1 controls many pathways Could you have EBV that leads to insulin resistance

https://multiplesclerosisnewstoday.com/news-posts/2016/02/23/university-of-northampton-researchers-find-no-evidence-of-a-link-between-environmental-radon-gas-and-multiple-sclerosis/

Oak ridge possibly had a cluster of birth defects associated with it including my specific defect which is rare 250,000 to 1 so to have a cluster is unusual I say possibly because officials declared it not so,it was just random chance but they are some odds

https://www.the-scientist.com/news-opinion/gene-therapy-effective-for-severe-combined-immunodeficiency-65750

Cytokines are the subject that always seems to come back and I could understand mecfs as the side effect of cytokines,even if these individual cytokines aren’t very elevated taken as a whole a little bit on each cytokine could add up to a lot

I don’t know how x ray machines work but I mean if the raw material that generates the radiation was just left out in the open so everybody was exposed especially in the earlier days where safety awareness might not of been as thorough

Everybody needs to be aware of bananas especially in bunches

For M.E hospital outbreaks could a faulty x ray machine generate enough radiation to be the cause Does the radon uk map tie in with higher MS cases I wondered (Orkney and Cornwall)

I think it deserves a lot more thought,I think it’s ground zero,nuclear bombs nuclear power,depleated uranium and nature causing genetic change I always thought whatever caused my mutations is the culprit two generations ago

Encephalopathy https://en.m.wikipedia.org/wiki/Encephalopathy